Patents by Inventor Ramesh Ramchandra Bhonde

Ramesh Ramchandra Bhonde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160206550
    Abstract: The present disclosure relates to a conditioned medium (CM) enriched with bioactive factor, its composition and the method of producing the CM. The method of obtaining the desired quantity of bioactive factors in conditioned medium comprises of pooling bone marrow derived mesenchymal stromal/stem cells, culturing the pooled cell and subjecting the cell culture to a cell feeding schedule at specified confluency and collecting the potent conditioned medium rich in bioactive factors at specific passage/time period. The method further aims at maximizing the probability of generating a conditioned medium with reduced biological variability and comprising large number of bioactive factors having specific biological function/property. The disclosure also relates to composition and formulation of the conditioned medium and their use in cosmetic and therapeutic areas.
    Type: Application
    Filed: June 18, 2014
    Publication date: July 21, 2016
    Applicant: STEMPEUTICS RESEARCH PVT. LTD.
    Inventors: Sudha BALASUBRAMANIAN, Swathi SUNDAR RAJ, Charan THEJ, Ramesh RAMCHANDRA BHONDE, Raviraja NEELAVAR SEETHARAM, Anish SEN MAJUMDAR
  • Patent number: 7074433
    Abstract: The present invention relates to a process for the cure and control of Diabetes mellitus using natural products isolated from Perna viridis.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: July 11, 2006
    Assignees: Council of Scientific and Industrial Research, Department of Biotechnology
    Inventors: Ramesh Ramchandra Bhonde, Anil Chatterji
  • Patent number: 6790659
    Abstract: The present invention provides a process for large scale in vitro production of amoebocytes of Indian Horseshoe Crab (Tachypleus gigas) (T. gigas) from dissected gill flaps of T. gigas, in Leibovitz L-15 culture medium concentration (2×), to provide enhanced generation of amoebocytes. The process comprises the steps of: dissecting gill flaps of T. gigas; washing the gill flaps with an antibiotic solution followed by alcohol; culturing the gill flaps in tissue culture plates of sterile saline on a Rocker platform; culturing further the gill flaps in Leibovitz L-15 culture medium (2×); purging the gill flaps with Tween 80 solution; and purging again the gill flaps with horseshoe crab serum, while keeping the gill flaps in the culture medium viable for 90 days by feeding with fresh medium at an interval of 10-15 days to enable the enhanced release of amoebocytes both within and outside the gill flaps.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: September 14, 2004
    Assignees: Council of Scientific and Industrial Research, National Center for Cell Sciences
    Inventors: Ramesh Ramchandra Bhonde, Anil Chatterji
  • Publication number: 20030186432
    Abstract: The present invention provides a process for large scale in vitro production of amoebocytes of Indian Horseshoe Crab (Tachypleus gigas) from dissected gill flaps of T. gigas, in Leibovitz culture medium concentration (2×L-15), having enhanced generation of amoebocytes, said process comprising the steps of: dissecting gill flaps of T. gigas; washing the gill flaps with an antibiotic solution followed by alcohol; culturing the gill flaps in tissue culture plates of sterile saline on a Rocker platform; culturing further the gill flapsin Leibovitz culture medium (2×L-15); purging the gill flaps with Tween 80 solution; and purging again the gill flaps with horse crab serum, keeping the culture viable for 90 days by feeding with fresh medium at an interval of 10-15 days to enable the enhanced release of amoebocytes both within and outside the gill flaps.
    Type: Application
    Filed: March 28, 2002
    Publication date: October 2, 2003
    Applicants: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH, NATIONAL CENTER FOR CELL SCIENCES
    Inventors: Ramesh Ramchandra Bhonde, Anil Chatterji
  • Publication number: 20020187201
    Abstract: The present invention relates to a process for the cure and control of Diabetes mellitus using natural products isolated from Perna viridis.
    Type: Application
    Filed: March 29, 2002
    Publication date: December 12, 2002
    Applicant: DEPARTMENT OF BIOTECHNOLOGY AND COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Ramesh Ramchandra Bhonde, Anil Chatterji