Patents by Inventor Ramon RUHÍ ROURA

Ramon RUHÍ ROURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10729728
    Abstract: The present invention refers to a process for preparing an animal brain extract. It also refers to the brain extract obtainable according to said process and to the use thereof as a medicine, in particular for the prevention and/or treatment of neurodegenerative diseases and disorders of the central nervous system. It also refers to compositions comprising this extract and to its use for preparing these compositions.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 4, 2020
    Assignee: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Daniel Martinez Puig, Pere Dalmau Castañares, Ramon Ruhi Roura, Joaquima Guix Salichs, Josep Ribas Maynou, Artur Alfocea Egüén, Antonio Garcia Pedrosa, Purificación Morales García, Pere Leon Martín, Marta Badias Eroles
  • Publication number: 20200102339
    Abstract: The present invention relates to sulphated disaccharides of formula (I) for use in the treatment of neuropathic pain. The present invention also relates to a pharmaceutical composition comprising the compound of formula (I) and at least one pharmaceutically acceptable excipient for use in the treatment of neuropathic pain. The compounds of formula (I) were effective in several experimental models of neuropathic pain for which reason these compounds can be used effectively for the treatment of different types of neuropathic pain and the clinical manifestations thereof, for example, mechanical allodynia or cold allodynia.
    Type: Application
    Filed: March 6, 2018
    Publication date: April 2, 2020
    Inventors: Josep VÉRGES MILANO, Eulàlia MONTELL BONAVENTURA, Ramon RUHÍ ROURA, Carlos Raúl ALÁEZ VERSÓN, Antonio GARCÍA GARCÍA, Manuela GARCÍA LÓPEZ, Juan Fernando PADÍN NOGUEIRA, Marcos MAROTO PÉREZ, Javier EGEA MÁlQUEZ
  • Publication number: 20180140638
    Abstract: The present invention refers to a process for preparing an animal brain extract. It also refers to the brain extract obtainable according to said process and to the use thereof as a medicine, in particular for the prevention and/or treatment of neurodegenerative diseases and disorders of the central nervous system. It also refers to compositions comprising this extract and to its use for preparing these compositions.
    Type: Application
    Filed: April 25, 2016
    Publication date: May 24, 2018
    Applicant: BIOIBERICA, S.A.
    Inventors: Josep ESCAICH FERRER, Daniel MARTINEZ PUIG, Pere DALMAU CASTAÑARES, Ramon RUHI ROURA, Joaquima GUIX SALICHS, Josep RIBAS MAYNOU, Artur ALFOCEA EGÜÉN, Antonio GARCIA PEDROSA, Purificación MORALES GARCÍA, Pere LEON MARTÍN, Marta BADIAS EROLES
  • Patent number: 9687525
    Abstract: The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: June 27, 2017
    Assignee: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Pere Dalmau Castanares, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Publication number: 20160228508
    Abstract: The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.
    Type: Application
    Filed: April 20, 2016
    Publication date: August 11, 2016
    Applicant: BIOIBERICA, S.A.
    Inventors: Josep ESCAICH FERRER, Pere DALMAU CASTANARES, Ana Maria TORRENT GIBERT, Ramon RUHI ROURA, Carlos Raul ALAEZ VERSON
  • Patent number: 9347081
    Abstract: The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: May 24, 2016
    Assignee: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Pere Dalmau Castanares, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Patent number: 8785416
    Abstract: The present invention relates to the use of a series of sulphated disaccharides for the preparation of a medicament for the treatment or prevention of a neurodegenerative and/or neurovascular disease, of a traumatic brain injury or of a traumatic spinal cord injury. The present invention also relates to the use of said sulphated disaccharides for the preparation of a neuroprotective medicament or of an antioxidant medicament. The neurodegenerative and/or neurovascular diseases are preferably: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and stroke.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: July 22, 2014
    Assignees: Bioiberica, S.A., Universidad Autonoma de Madrid
    Inventors: Josep Verges Milano, Antonio Garcia Garcia, Ramon Ruhi Roura, Eulalia Montell Bonaventura, Manuela Garcia Lopez, Carlos Raul Alaez Verson, Josep Escaich Ferrer, Javier Egea Maiquez, Pilar Negredo Madrigal, Silvia Lorrio Gonzalez
  • Publication number: 20140113861
    Abstract: The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method. Said cartilage product is useful in the treatment or prevention of wounds, ulcers, burns, psoriasis, osteoarthritis, synovitis, osteoporosis, osteopenia, diseases of the tendons and ligaments, periodontal diseases, signs of skin aging, the harmful effects of ultraviolet radiation exposure or stretch marks.
    Type: Application
    Filed: April 16, 2012
    Publication date: April 24, 2014
    Applicant: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Pere Dalmau Castanares, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Patent number: 8445462
    Abstract: The present invention relates to compositions comprising chondroitin sulphate and mannosamine or a derivative thereof. The mannosamine derivative is preferably N-acetylmannosamine. The compositions may comprise glucosamine. Said compositions are useful in the treatment or prevention of degenerative joint diseases, preferably of osteoarthritis, in the treatment or prevention of tendon or ligament diseases, disorders or injuries and of immune system diseases, preferably of rheumatoid arthritis.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: May 21, 2013
    Assignee: Bioiberica, S.A.
    Inventors: Josep Escaich Ferrer, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Pere Dalmau Castanares
  • Patent number: 8394781
    Abstract: Disaccharides for the treatment of tendons, ligaments and bones. The present invention relates to the use of a series of disaccharides, as well as of compositions containing them, for the preparation of a medicament for the treatment or prevention of a tendon, ligament or bone disease, disorder or injury. The present invention also relates to the new compositions comprising a disaccharide in combination with inulin polysulphate, a glycosaminoglycan, a growth factor or cells. The glycosaminoglycan is preferably chondroitin sulphate or hyaluronic acid and the growth factor is IFG-1.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: March 12, 2013
    Assignee: Bioiberica, S.A.
    Inventors: Josep Escaich Ferrer, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Publication number: 20120309707
    Abstract: The present invention relates to the use of a series of sulphated disaccharides for the preparation of a medicament for the treatment or prevention of a neurodegenerative and/or neurovascular disease, of a traumatic brain injury or of a traumatic spinal cord injury. The present invention also relates to the use of said sulphated disaccharides for the preparation of a neuroprotective medicament or of an antioxidant medicament. The neurodegenerative and/or neurovascular diseases are preferably: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and stroke.
    Type: Application
    Filed: December 22, 2010
    Publication date: December 6, 2012
    Applicants: UNIVERSIDAD AUTONOMA DE MADRID, BIOIBERICA, S.A.
    Inventors: Josep Verges Milano, Antonio Garcia Garcia, Ramon Ruhi Roura, Eulalia Montell Bonaventura, Manuela Garcia Lopez, Carlos Raul Alaez Verson, Josep Escaich Ferrer, Javier Egea Maiquez, Pilar Negredo Madrigal, Silvia Lorrio Gonzalez
  • Patent number: 7943598
    Abstract: The present invention relates to the use of an organic glucosamine salt selected from glucosamine glucuronate, glucosamine ascorbate, glucosamine malate, glucosamine hydrogen malate, glucosamine citrate, glucosamine hydrogen citrate, and glucosamine dihydrogen citrate for the preparation of a medicament for the treatment of arthrosis and inflammation and pain associated with arthrosis. The present invention also relates to the use of an organic glucosamine salt, selected from the ones mentioned above, for the preparation of a nutritional supplement acting as a chondroprotector, to nourish the cartilage, protect the joints, prevent water deficit in the tissues that form the joint, improve the joints' functional capacity, elasticity, and flexibility, and prevent and revert the physical overexertion syndrome in athletes, and the effects associated therewith.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: May 17, 2011
    Assignee: Bioiberica, S.A.
    Inventors: Josep Escaich Ferrer, Ramon Ruhi Roura, Ana Maria Torrent Gibert
  • Publication number: 20100286086
    Abstract: The present invention relates to compositions comprising chondroitin sulphate and mannosamine or a derivative thereof. The mannosamine derivative is preferably N-acetylmannosamine. The compositions may comprise glucosamine. Said compositions are useful in the treatment or prevention of degenerative joint diseases, preferably of osteoarthritis, in the treatment or prevention of tendon or ligament diseases, disorders or injuries and of immune system diseases, preferably of rheumatoid arthritis.
    Type: Application
    Filed: December 17, 2008
    Publication date: November 11, 2010
    Applicant: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Pere Dalmau Castanares
  • Patent number: 7816329
    Abstract: The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group constituting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: October 19, 2010
    Assignee: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Josep Escaich Ferrer, August Lodewijk Verbruggen, Josep Verges Milano, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Publication number: 20100129331
    Abstract: The present invention relates to the use of a series of disaccharides, as well as of compositions containing them, for the preparation of a medicament for the treatment or prevention of a tendon, ligament or bone disease, disorder or injury. The present invention also relates to the new compositions comprising a disaccharide in combination with inulin polysulphate, a glycosamino-glycan, a growth factor or cells. The glycosaminoglycan is preferably chondroitin sulphate or hyaluronic acid and the growth fact is IFG-1.
    Type: Application
    Filed: May 15, 2008
    Publication date: May 27, 2010
    Applicant: BIOIBERICA, S.A.
    Inventors: Josep Escaich Ferrer, Ana Maria Torrent Gibert, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Publication number: 20080051350
    Abstract: The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group consisting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.
    Type: Application
    Filed: February 11, 2005
    Publication date: February 28, 2008
    Applicant: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Josep Escaich Ferrer, August Lodewijk Verbruggen, Josep Verges Milano, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Publication number: 20070244070
    Abstract: The present invention relates to the use of an organic glucosamine salt selected from glucosamine glucuronate, glucosamine ascorbate, glucosamine malate, glucosamine hydrogen malate, glucosamine citrate, glucosamine hydrogen citrate, and glucosamine dihydrogen citrate for the preparation of a medicament for the treatment of arthrosis and inflammation and pain associated with arthrosis. The present invention also relates to the use of an organic glucosamine salt, selected from the ones mentioned above, for the preparation of a nutritional supplement acting as a chondroprotector, to nourish the cartilage, protect the joints, prevent water deficit in the tissues that form the joint, improve the joints' functional capacity, elasticity, and flexibility, and prevent and revert the physical overexertion syndrome in athletes, and the effects associated therewith.
    Type: Application
    Filed: June 23, 2005
    Publication date: October 18, 2007
    Applicant: BIOIBERICA, S.A.
    Inventors: Jose Escaish Ferrer, Ramon Ruhi Roura, Ana Torrent Gibert
  • Patent number: 7141556
    Abstract: This invention relates to a process for the preparation of glucosamine sulfate, glucosamine hydroiodide, glucosamine pyruvate, glucosamine phosphate or their mixtures with glucosamine hydrochloride, by electrodialysis. Starting from glucosamine hydrochloride, the exchange of the Cl? for an anion selected from the group consisting of SO4 ?2, I?, CH3COCOO? and PO4?3 takes place during the process. The electrodialyser comprises a cathode, anode, and means of separation composed of anion exchange membranes, cation exchange membranes, bipolar membranes or by other suitable means of separation. This invention also relates to a glycosamine sulphate containing chlorides obtainable by the process, and its therapeutic use.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: November 28, 2006
    Assignee: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Ricard Mis Vizcaino, Ramon Ruhi Roura, Ana Maria Torrent Gibert, Vicente Montiel Leguey, Vicente Garcia Garcia, Eduardo Exposito Rodriguez, Antonio Aldaz Riera, Carlos Raul Alaez Verson
  • Publication number: 20050014720
    Abstract: This invention relates to a process for the preparation of glucosamine hydroiodide, glucosamine pyruvate, glucosamine phosphate or their mixtures with glucosamine hydrochloride, by electrodialysis. Starting from glucosamine hydrochloride, the exchange of the Cl? for an anion selected from the group consisting of SO4 ?2, I?, CH3COCOO? and PO4?3 takes place during the process. The electrodialysis, that comprises a cathode, anode, and means of separation composed of anion exchange membranes, cation exchange membranes, bipolar membranes or by other suitable means of separation. This invention also relates to a glycosamine sulphate containing chlorides obtainable by the process, and its therapeutic use.
    Type: Application
    Filed: December 13, 2002
    Publication date: January 20, 2005
    Inventors: Francisco Vila Pahi, Ricard Mis Vizcaino, Ramon Ruhi Roura, Ana Maria Torrent Gibert, Vicente Montiel Leguey, Vicente Garcia Garcia, Eduardo Exposito Rodriguez, Antonio Aldaz Riera, Carlos Alaez Verson
  • Patent number: 6680304
    Abstract: The invention relates to novel disaccharides of formula (I), wherein R1 is selected from the group consisting of hydrogen, linear or branched (C1-C4) alkyl, phenylalkyl with less than ten carbon atoms and —COCH3; R2 is selected from the group consisting of hydrogen, —COCH3 and SO3M; R3 is selected from the group consisting of hydrogen, linear or branched (C1-C4) alkyl, phenylalkyl with less than ten carbon atoms, —COCH3 and y —COPh, Ph being phenyl; G is selected from amongst —COOR4 and —COOM, R4 is selected from the group consisting of hydrogen, (C1-C2)-alkyl and arylalkyl with less than sixteen carbon atom; A is selected from the group consisting of hydrogen, —SO3H, —SO3M and —COCH3; B is selected from the group consisting of hydrogen, —SO3H, —SO3M and —COCH3, wherein either A or B are necessarily either —SO3H or —SO3M, M being a an organic or metallic cation.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: January 20, 2004
    Assignee: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Francesc Flores Salgado, Ramon Ruhi Roura, Narcís Arnau Pastor