Patents by Inventor Rangachari Narasimhan

Rangachari Narasimhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230092389
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Application
    Filed: May 9, 2022
    Publication date: March 23, 2023
    Inventors: Carlos SCHULER, Rangachari NARASIMHAN, Luiz BELARDINELLI, Prashanti MADHAVAPEDDI
  • Patent number: 11547663
    Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: January 10, 2023
    Assignees: InCarda Therapeutics, Inc., The Regents of the University of California
    Inventors: Rangachari Narasimhan, Gregory Marcus
  • Publication number: 20210228825
    Abstract: Disclosed herein is a method for evaluating Brugada syndrome (BrS) in a subject in need thereof. In some embodiments, the method comprises administering an aerosol of a sodium channel blocker to the subject. Also disclosed herein are compositions, unit doses, and kits for evaluating Brugada syndrome in a subject in need thereof.
    Type: Application
    Filed: June 5, 2019
    Publication date: July 29, 2021
    Inventors: Rangachari NARASIMHAN, Luiz BELARDINELLI, Carlos A. SCHULER
  • Publication number: 20200360280
    Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.
    Type: Application
    Filed: June 2, 2020
    Publication date: November 19, 2020
    Inventors: Rangachari Narasimhan, Gregory Marcus
  • Patent number: 10744087
    Abstract: Disclosed herein are methods, formulations, and kits for treating or preventing a heart condition, e.g., cardiac arrhythmia, e.g., atrial arrhythmia, using selective ?1 adrenergic receptor blockers. Also disclosed herein are methods, formulations, and kits for treating a heart condition via inhalation or intranasal spray administration of selective ?1 adrenergic receptor blocker and class I antiarrhythmic agent.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: August 18, 2020
    Assignee: InCarda Therapeutics, Inc.
    Inventors: Luiz Belardinelli, Rangachari Narasimhan, Carlos Schuler
  • Publication number: 20200179278
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Application
    Filed: February 12, 2020
    Publication date: June 11, 2020
    Inventors: Carlos SCHULER, Rangachari NARASIMHAN, Luiz BELARDINELLI, Prashanti MADHAVAPEDDI
  • Publication number: 20200179279
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Application
    Filed: February 12, 2020
    Publication date: June 11, 2020
    Inventors: Carlos SCHULER, Rangachari NARASIMHAN, Luiz BELARDINELLI, Prashanti MADHAVAPEDDI
  • Patent number: 10668015
    Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 2, 2020
    Assignees: InCarda Therapeutics, Inc., The Regents of the University of California
    Inventors: Rangachari Narasimhan, Gregory Marcus
  • Patent number: 10660578
    Abstract: Disclosed herein are methods of treating cardiac arrhythmia with electronic monitoring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: May 26, 2020
    Assignee: InCarda Therapeutics, Inc.
    Inventors: Rangachari Narasimhan, Luiz Belardinelli, Carlos A. Schuler
  • Patent number: 10441537
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: October 15, 2019
    Assignee: InCarda Therapeutics, Inc.
    Inventors: Carlos Schuler, Rangachari Narasimhan, Luiz Belardinelli, Prashanti Madhavapeddi
  • Publication number: 20190290581
    Abstract: Disclosed herein are methods, formulations, and kits for treating or preventing a heart condition, e.g., cardiac arrhythmia, e.g., atrial arrhythmia, using selective ?1 adrenergic receptor blockers. Also disclosed herein are methods, formulations, and kits for treating a heart condition via inhalation or intranasal spray administration of selective ?1 adrenergic receptor blocker and class I antiarrhythmic agent.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Inventors: Luiz BELARDINELLI, Rangachari NARASIMHAN, Carlos SCHULER
  • Publication number: 20190083396
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 21, 2019
    Inventors: Carlos SCHULER, Rangachari NARASIMHAN, Luiz BELARDINELLI, Prashanti MADHAVAPEDDI
  • Publication number: 20190060230
    Abstract: Methods of treating atrial arrhyththmia include administering an effective amount of at least one antiarrthythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heat at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit does, aerosols, and kits are also contemplated.
    Type: Application
    Filed: October 26, 2018
    Publication date: February 28, 2019
    Inventors: Carlos A. SCHULER, Rangachari NARASIMHAN
  • Publication number: 20180325818
    Abstract: Methods of treating a heart condition include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. Nebulized drug product and kits are also contemplated.
    Type: Application
    Filed: May 10, 2018
    Publication date: November 15, 2018
    Inventors: Carlos SCHULER, Rangachari NARASIMHAN, Luiz BELARDINELLI, Prashanti MADHAVAPEDDI
  • Publication number: 20180318213
    Abstract: Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated.
    Type: Application
    Filed: June 20, 2018
    Publication date: November 8, 2018
    Inventors: Carlos A. SCHULER, Rangachari NARASIMHAN
  • Publication number: 20180303435
    Abstract: Disclosed herein are methods of treating cardiac arrhythmia with electronic monitoring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia.
    Type: Application
    Filed: March 22, 2018
    Publication date: October 25, 2018
    Inventors: Rangachari NARASIMHAN, Luiz BELARDINELLI, Carlos A. SCHULER
  • Publication number: 20180296480
    Abstract: Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated.
    Type: Application
    Filed: June 20, 2018
    Publication date: October 18, 2018
    Inventors: Carlos A. SCHULER, Rangachari NARASIMHAN
  • Patent number: 10045939
    Abstract: Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: August 14, 2018
    Assignee: InCarda Therapeutics, Inc.
    Inventors: Carlos A. Schuler, Rangachari Narasimhan
  • Patent number: 10010294
    Abstract: Disclosed herein are methods of treating cardiac arrhythmia with electronic monitoring in a timely manner. Also disclosed herein are systems for electronic monitoring of cardiac arrhythmia.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: July 3, 2018
    Assignee: INCARDA THERAPEUTICS, INC.
    Inventors: Rangachari Narasimhan, Luiz Belardinelli, Carlos A. Schuler
  • Publication number: 20180008540
    Abstract: Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (ACS) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.
    Type: Application
    Filed: January 20, 2016
    Publication date: January 11, 2018
    Inventors: Rangachari Narasimhan, Gregory Marcus