Patents by Inventor Rashmi RAVICHANDRAN

Rashmi RAVICHANDRAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11771755
    Abstract: Nanostructures and nanostructure-based vaccines that display antigens capable of eliciting immune responses to infectious agents such as bacteria, viruses, and pathogens are provided. Some vaccines are useful for preventing or decreasing the severity of infection with an infectious agent, including, for example and without limitation, lyme disease, pertussis, herpes virus, orthomyxovirus, paramyxovirus, pneumovirus, filovirus, flavivirus, reovirus, retrovirus, meningococcus, or malaria. The antigens may be attached to the core of the nanostructure either non-covalently or covalently, including as a fusion protein or by other means. Multimeric antigens may optionally be displayed along a symmetry axis of the nanostructure. Also provided are proteins and nucleic acid molecules encoding such proteins, vaccine compositions, and methods of administration.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: October 3, 2023
    Assignee: University of Washington
    Inventors: Neil King, David Baker, Lance Stewart, Brooke Fiala, Daniel Ellis, Lauren Carter, Rashmi Ravichandran, George Ueda, Jorge Fallas, Una Nattermann
  • Publication number: 20230250134
    Abstract: Polypeptide inhibitors of SARS-COV-2 are disclosed comprising an amino acid sequence at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS: 1-17, 19-21, 23-34 and 100-101, and their use for treating and limiting development of SARS-COV-2 infection.
    Type: Application
    Filed: May 25, 2021
    Publication date: August 10, 2023
    Inventors: Longxing CAO, Brian COVENTRY, Inna GORESHNIK, Lauren MILLER, David BAKER, Lisa KOZODOY, John BOWEN, Lauren CARTER, James Brett CASE, Michael DIAMOND, Natasha EDMAN, Andrew HUNT, Michael Christopher JEWETT, Cassandra Jean OGOHARA, Young-jun PARK, Rashmi RAVICHANDRAN, Lance Joseph STEWART, David VEESLER, Bastian VOGELI, Alexandra C. WALLS, Kejia WU, Scott BOYKEN, George UEDA
  • Publication number: 20200397886
    Abstract: The present disclosure provides nanostructures and nanostructure-based vaccines. Some nanostructures of the present disclosure display antigens capable of eliciting immune responses to infectious agents such as bacteria, viruses, and pathogens. Some vaccines of the present disclosure are useful for preventing or decreasing the severity of infection with an infectious agent, including, for example and without limitation, lyme disease, pertussis, herpes virus, orthomyxovirus, paramyxovirus, pneumovirus, filovirus, flavivirus, reovirus, retrovirus, meningococcus, or malaria. The antigens may be attached to the core of the nanostructure either non-covalently or covalently, including as a fusion protein or by other means disclosed herein. Multimeric antigens may optionally be displayed along a symmetry axis of the nanostructure. Also provided are proteins and nucleic acid molecules encoding such proteins, vaccine compositions, and methods of administration.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 24, 2020
    Inventors: Neil KING, David BAKER, Lance STEWART, Brooke FIALA, Daniel ELLIS, Lauren CARTER, Rashmi RAVICHANDRAN, George UEDA, Jorge FALLAS, Una NATTERMAN