Patents by Inventor Remco Den Dulk

Remco Den Dulk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200158604
    Abstract: A system for preparing a calibrated volume of blood plasma that includes a plurality of parts: a device for preparing the calibrated volume of blood plasma, which is in the form of a single card; a pneumatic-type actuating system SP; a treatment and command unit UC configured such as to execute a command sequence of different pneumatic command points of the pneumatic actuation system with a view to obtaining, from a taken blood sample, the calibrated volume of blood plasma. The device includes three distinct modules: a fluidic connection module M1 onto which a blood sampling device may be connected; a module M2 for separation of the blood plasma contained in the blood sample; a module M3 for obtaining at least one calibrated volume of blood plasma, after separation.
    Type: Application
    Filed: November 14, 2019
    Publication date: May 21, 2020
    Applicant: Commissariat A L'Energie Atomique et aux Energies Alternatives
    Inventors: Myriam-Laure Cubizolles, Manuel Alessio, Remco Den Dulk, Frederic Revol-Cavalier
  • Patent number: 10160947
    Abstract: A device and method for lysing biological species present in a fluid includes implementing a rough surface against which the objects to be lysed are crushed by a shearing motion. A device for mechanically lysing biological species has a first and second wall mounted movable relative to each other, between an initial position in which the walls are separated from each other, and a lysing position in which the first wall presses against the second wall. The first and second walls also are mounted shearingly movable relative to each other in the lysing position. At least one of the first or second walls has a rough bearing surface against the other wall and has a mean surface roughness parameter Ra of between 0.2 ?m and 10 ?m, and preferably between 0.2 ?m and 3 ?m.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: December 25, 2018
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Anne-Gaelle Bourdat, Antonio Viana, Remco Den Dulk
  • Patent number: 10092903
    Abstract: The present invention discloses microfluidic devices with a valve-like structure (3), through which magnetic particles can be transported with minimal transport of fluids. This allows sequential processing of the magnetic particles.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: October 9, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Menno Willem Jose Prins, Joost Hubert Maas, Albert Hendrik Jan Immink, Dirkjan Bernhard Van Dam, Maatje Koets, Michel J. M. Bruyninckx, Thea Van Der Wijk, Marius Iosif Boamfa, Remco Den Dulk
  • Publication number: 20170218326
    Abstract: A device and method for lysing biological species present in a fluid includes implementing a rough surface against which the objects to be lysed are crushed by a shearing motion. A device for mechanically lysing biological species has a first and second wall mounted movable relative to each other, between an initial position in which the walls are separated from each other, and a lysing position in which the first wall presses against the second wall. The first and second walls also are mounted shearingly movable relative to each other in the lysing position. At least one of the first or second walls has a rough bearing surface against the other wall and has a mean surface roughness parameter Ra of between 0.2 ?m and 10 ?m, and preferably between 0.2 ?m and 3 ?m.
    Type: Application
    Filed: May 27, 2015
    Publication date: August 3, 2017
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Anne-Gaelle Bourdat, Antonio Viana, Remco Den Dulk
  • Patent number: 9272290
    Abstract: The invention relates to a method and an apparatus (100) for the enrichment of magnetic particles (1) in a sample fluid. The sample fluid is provided in a sample cartridge (2) between a first pole (111) and a second pole (112) of an actuator magnet (110). A minimal magnetic flux as well as a minimal magnetic gradient are then established inside the sample fluid, wherein their values depend on the particular magnetic particles (1) and the sample fluid under consideration. In a preferred embodiment, the first pole (111) has a single tip (T).
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: March 1, 2016
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Matthias Irmscher, Remco Den Dulk, Menno Willem Jose Prins
  • Publication number: 20120161754
    Abstract: The invention relates to a method and an apparatus (100) for the enrichment of magnetic particles (1) in a sample fluid. The sample fluid is provided in a sample cartridge (2) between a first pole (111) and a second pole (112) of an actuator magnet (110). A minimal magnetic flux as well as a minimal magnetic gradient are then established inside the sample fluid, wherein their values depend on the particular magnetic particles (1) and the sample fluid under consideration. In a preferred embodiment, the first pole (111) has a single tip (T).
    Type: Application
    Filed: July 12, 2010
    Publication date: June 28, 2012
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Matthias Irmscher, Remco Den Dulk, Menno Willem Jose Prins
  • Publication number: 20100273142
    Abstract: The present invention discloses microfluidic devices with a valve-like structure (3), through which magnetic particles can be transported with minimal transport of fluids. This allows sequential processing of the magnetic particles.
    Type: Application
    Filed: December 16, 2008
    Publication date: October 28, 2010
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Menno Willem Jose Prins, Joost Hubert Maas, Albert Hendrik Jan Immink, Dirkjan Bernhard Van Dam, Maatje Koets, Michel J.M. Bruyninckx, Thea Van Der Wijk, Marius losif Boamfa, Remco Den Dulk