Patents by Inventor René Verwaal

René Verwaal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120040422
    Abstract: The present invention relates to a process for the production of a dicarboxylic acid and ethanol which comprises fermenting a genetically modified yeast in a suitable fermentation medium under anaerobic conditions at a pH value of between 1 and 5 and producing the dicarboxylic acid and ethanol.
    Type: Application
    Filed: March 23, 2010
    Publication date: February 16, 2012
    Applicant: DSM IP ASSET B.V.
    Inventors: Mickel Leonardus August Jansen, Maarten Job Van De Graaf, René Verwaal
  • Publication number: 20110318795
    Abstract: The present invention relates to a recombinant fungus comprising an enzyme which catalyses the conversion of malic acid to fumaric acid in the cytosol. The invention further relates to a process for the production of a dicarboxylic acid such as fumaric acid and succinic acid, wherein the recombinant fungus is used.
    Type: Application
    Filed: November 14, 2008
    Publication date: December 29, 2011
    Inventors: René Verwaal, Liang Wu, Robbertus Antonius Damveld, Cornelis Maria Jacobus Sagt
  • Publication number: 20110229945
    Abstract: The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more cost-effective than existing processes in which the salt is produced which during recovery has to be converted to the acid. It also leads to a simpler and more convenient downstream processing.
    Type: Application
    Filed: May 20, 2009
    Publication date: September 22, 2011
    Inventors: Mickel Leonardus August Jansen, René Verwaal
  • Publication number: 20110143405
    Abstract: The present invention relates to a recombinant yeast comprising a nucleotide sequence encoding a heterologous enzyme that catalyses the conversion of malic acid to fumaric acid. The invention further relates to a process for the production of a dicarboxylic acid wherein the yeast according to the present invention is used.
    Type: Application
    Filed: November 14, 2008
    Publication date: June 16, 2011
    Inventors: Rene Verwaal, Liang Wu, Robbertus Antonius Damveld, Cornelis Maria Jacobus Sagt
  • Publication number: 20110081694
    Abstract: The present invention relates to a recombinant eukaryotic microbial cell comprising a nucleotide sequence encoding a heterologous enzyme catalysing the conversion from phosphoenolpyruvate to oxaloacetate whereby ATP is generated. The invention further relates to a process for the preparation of a dicarboxylic acid such as succinic acid and fumaric acid, comprising fermenting the eukaryotic microbial cell according to the invention in a suitable fermentation medium.
    Type: Application
    Filed: November 14, 2008
    Publication date: April 7, 2011
    Inventors: Rene Verwaal, Liang Wu, Robbertus Antonius Damveld, Cornelis Maria Jacobus Sagt