Abstract: An active implantable medical device, in particular a pacemaker, defibrillator and/or cardiovertor of the multisite type providing resynchronization of the ventricles electrodes are placed in at least two sites, right and left, and are connected to a circuit for the collection of cardiac signals, to detect a depolarization potential. Electrodes also are connected to a stimulation circuit, to apply stimulation pulses to at least some of the sites. The device provides resynchronization of the ventricular contraction, by establishing a delay between the times of application of the respective stimulation pulses on the right ventricle (RV) and left ventricle (LV), determining a parameter (z) representative of the degree of synchronization between ventricles, and varying the delay in the direction of the improvement of the aforesaid representative parameter. The parameter is a bio-impedance measurement.

Abstract: Apparatus and methods for adjusting an electrical parameter of an electronic device, notably of an active implantable medical device such as a pacemaker or cardiac defibrillator, and an implementing monolithic integrated circuit for conducting the adjustment.

Abstract: A process to configure an implantable active medical device by adjusting a parameter. For each parameter to be adjusted, the steps of the process are: the determination of a code of adjustment for a given parameter value, writing of the code of adjustment to alter a circuit configuration, and the verification of the validity of the set code. A verified code is then permanently written by straining of selected diodes. The code of adjustment is thus used to adjust a circuit configuration to alter the sensed operating parameter value so that, after straining, the adjusted parameter value of the configured circuit falls in or at a desired range or value. Suitable circuit parameters include clock frequency and reference voltage levels, as are found in cardiac pacemakers and defibrillators.

Abstract: An active implantable medical device, particularly a cardiac pacemaker or defibrillator, having a protection circuit that is effective against electromagnetic perturbations of external origin. The active implantable device is characterized in that at least all active components of the protection circuit (58, 60, 94, 98) are integrated components in a monolithically integrated microchip (16) including a control signal and circuits to commute selectively signals collected by external electrodes to the device for processing. In particular, the commutation circuits comprise static switches (24, 24', 28, 28', 38, 38', 40, 40', 44, 44', 46, 46', 50, 50', 54), and the control signal is a control voltage (VSUB, VCC) that is greater than the voltage (VPILE) of the battery of the device.