Abstract: A target value of a performance metric associated with an advertising schedule can be obtained at an automated media content scheduling system. An upper boundary value indicating a value of the performance metric at which corrective action to decrease a predicted value of the performance metric is to be taken can be determined. A lower boundary value indicating a value of the performance metric at which corrective action to increase the predicted value of the performance metric is to be taken can also be determined. Information indicating the predicted value of the performance metric can be received at the automated media content scheduling system. The advertising schedule can be continually adjusted to maintain the predicted value of the performance metric between the upper boundary value and the lower boundary value.

Abstract: Upper and lower boundary values can be determined based on estimated gross rating point (GRP) values associated with performance of an advertising schedule in a particular market. Audience data associated with the particular market, and a de-duplication weighting can be applied to the audience data to generate weighted audience data. Based at least in part on the weighted audience data, actual GRP values can be determined, and associated with the performance of the advertising schedule in the particular market. A predicted GRP trend can be determined based on those actual GRP values. The advertising schedule can be continually adjusted, in some cases in real time, to maintain the predicted GRP trend between the upper and lower boundary values.

Abstract: Multiple filtering criteria derived from consumer surveys can be used to adjust an advertising schedule to achieve improved performance. Historical performance data related to performance factors, such as gross rating points, can be filtered using the multiple filtering criteria. The filtered data can then be used as the basis for predicting future performance of an advertisement or advertising campaign. The historical data can be updated as new performance data becomes available, and the predicted future performance updated. An advertising schedule can be adjusted to maintain performance factors within designated upper and lower limits.

Abstract: Individual chunks of a message are signed with their originators' signatures, thereby providing traceability in threaded messages so that every contributor's content as well as modifications thereof can be identified.

Abstract: A meeting management application that permits the manipulation of meetings by groups is provided. The meeting management application incorporates or is associated with a scheduling application for receiving and maintaining meeting information. The scheduling application may additionally check for conflicts between scheduled meetings and other meetings and events. The meeting management application may additionally include or be associated with a grouping application. The grouping application may permit the creation of groups of meetings having one or more specified items of associated information. Once a group of meetings is defined, modifications to information associated with each meeting within the group can be applied to the included meetings globally.

Abstract: An automatic appointment reminder system uses location and/or direction of travel of the reminder recipient relative to appointments to affect the time of sending of appointment reminders to the user, and thus enhances the user's ability to be on-time for appointments.

Abstract: Multiple filtering criteria derived from consumer surveys can be used to adjust an advertising schedule to achieve improved performance. Historical performance data related to performance factors, such as gross rating points, can be filtered using the multiple filtering criteria. The filtered data can then be used as the basis for predicting future performance of an advertisement or advertising campaign. The historical data can be updated as new performance data becomes available, and the predicted future performance updated. An advertising schedule can be adjusted to maintain performance factors within designated upper and lower limits.

Abstract: Disclosed is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol and pharmaceutically acceptable salts and solvates thereof, methods for preparing them, pharmaceutical compositions comprising them, and processes for their preparation; also disclosed is a method of treating depression, attention deficit hyperactivity disorder (ADHD), obesity, migraine, sexual dysfunction, Parkinson's disease, Alzheimer's disease, or addiction to cocaine or nicotine-containing (especially tobacco) products using such compound, salts, solvates or compositions.

Abstract: Disclosed is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol and pharmaceutically acceptable salts and solvates thereof, methods for preparing them, pharmaceutical compositions comprising them, and processes for their preparation; also disclosed is a method of treating depression, attention deficit hyperactivity disorder (ADHD), obesity, migraine, sexual dysfunction, Parkinson's disease, Alzheimer's disease, or addiction to cocaine or nicotine-containing (especially tobacco) products using such compound, salts, solvates or compositions.

Abstract: Disclosed is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol and pharmaceutically acceptable salts and solvates thereof, methods for preparing them, pharmaceutical compositions comprising them, and processes for their preparation; also disclosed is a method of treating depression, attention deficit hyperactivity disorder (ADHD), obesity, migraine, sexual dysfunction, Parkinson's disease, Alzheimer's disease, or addiction to cocaine or nicotine-containing (especially tobacco) products using such compound, salts, solvates or compositions.

Abstract: A system for supplying an implement with hydraulic fluid includes a first hydraulic pump generating a first flow, a second hydraulic pump generating a second flow and a valve assembly adapted to be coupled to the implement and coupled to the first and second flows. The valve assembly couples the first flow to the implement. The valve assembly also selectively adds the second flow to the first flow to provide a low flow or a high flow. The valve assembly couples the first flow to the implement via a first coupling in response to a first signal and via a second coupling in response to a second signal. The system further includes a manually operable control coupled to the valve assembly and movable between the first position which the first signal is generated, a second position in which the second signal is generated and a third position in which a third signal is generated. The system also includes a foot pedal control coupled to the manually operable control and to the valve assembly.

Abstract: The handle of the toothbrush is in the general form of an animal (e.g., a quadriped) having its body-supported when not in use in a generally horizontal position. The handle is manually encircled and grasped by the hand with the thumb extending under and around the lower part of the body and with the palm and fingers extending over and around the upper part of the body portion as in a fist. The brush head of the toothbrush extends from an end of the handle. When the brush is not in use, it is adapted to rest on a flat surface with the bristles spaced from such surface. The device is adapted to motivate children to acquire and maintain desirable lifelong habits of good dental hygiene, it is easy for children to use, and it has enhanced sanitary features not found in the common types of toothbrushes presently available in the marketplace.