Patents by Inventor Richard A. Gemeinhart

Richard A. Gemeinhart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogels for delivery of therapeutic polypeptides
    Patent number: 9457101
    Abstract: Disclosed herein is a hydrogel composition comprising a polymer covalently linked to glutathione (GSH). Also disclosed herein is a method for providing localized delivery of one or more agents in a subject suffering from a disease. The method comprises administering to the subject a GST/GSH affinity hydrogel comprising a therapeutically effective amount of the one or more agents.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: October 4, 2016
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Richard Gemeinhart, Jason Buhrman, Jamie Rayahin
  • HYDROGELS FOR DELIVERY OF THERAPEUTIC POLYPEPTIDES
    Publication number: 20150258211
    Abstract: Disclosed herein is a hydrogel composition comprising a polymer covalently linked to glutathione (GSH). Also disclosed herein is a method for providing localized delivery of one or more agents in a subject suffering from a disease. The method comprises administering to the subject a GST/GSH affinity hydrogel comprising a therapeutically effective amount of the one or more agents.
    Type: Application
    Filed: June 6, 2013
    Publication date: September 17, 2015
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Richard Gemeinhart, Jason Buhrman, Jamie Rayahin
  • Superporous hydrogel with cells encapsulated therein and method for producing the same
    Patent number: 8414879
    Abstract: The present invention is a superporous hydrogel with cells encapsulated within the hydrogel matrix, and a method for producing the same.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: April 9, 2013
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: Richard A. Gemeinhart
  • Composition and method for providing localized delivery of a therapeutic agent
    Patent number: 7943569
    Abstract: The present invention is a composition for providing localized delivery of a therapeutic agent to a subject. The instant composition is a hydrophilic matrix-based prodrug system, wherein a protease substrate peptide acts as extracellular protease degradable spacer binding the therapeutic agent to a hydrophilic matrix. Release of the therapeutic agent is achieved by localized activity of extracellular proteases thereby providing minimal toxicity of the therapeutic agent and maximum release with protease activity. Methods for producing the instant composition and providing localized delivery of a therapeutic agent to a subject are also provided.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: May 17, 2011
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Richard A. Gemeinhart, Jovita R. Tauro
  • Hybrid superporous hydrogel scaffold for cornea regeneration
    Publication number: 20100080840
    Abstract: The present invention features a hybrid superporous hydrogel scaffold for cornea regeneration and a method for producing the same. The hybrid hydrogel is composed of a superporous hydrogen matrix with collagen and cells embedded within the pores of the matrix.
    Type: Application
    Filed: July 29, 2009
    Publication date: April 1, 2010
    Inventors: Michael Cho, Arpita Kadakia, Ali Djalilian, Richard A. Gemeinhart
  • Superporous hydrogel with cells encapsulated therein and method for producing the same
    Publication number: 20090291115
    Abstract: The present invention is a superporous hydrogel with cells encapsulated within the hydrogel matrix, and a method for producing the same.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 26, 2009
    Inventor: Richard A. Gemeinhart
  • Composition and method for providing localized delivery of a therapeutic agent
    Publication number: 20080131510
    Abstract: The present invention is a composition for providing localized delivery of a therapeutic agent to a subject. The instant composition is a hydrophilic matrix-based prodrug system, wherein a protease substrate peptide acts as extracellular protease degradable spacer binding the therapeutic agent to a hydrophilic matrix. Release of the therapeutic agent is achieved by localized activity of extracellular proteases thereby providing minimal toxicity of the therapeutic agent and maximum release with protease activity. Methods for producing the instant composition and providing localized delivery of a therapeutic agent to a subject are also provided.
    Type: Application
    Filed: November 16, 2007
    Publication date: June 5, 2008
    Inventors: Richard A. Gemeinhart, Jovita R. Tauro