Patents by Inventor Richard Alexander Grant
Richard Alexander Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230293812Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: ApplicationFiled: March 22, 2023Publication date: September 21, 2023Applicant: ViaCyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Patent number: 11642455Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: GrantFiled: December 15, 2021Date of Patent: May 9, 2023Assignee: ViaCyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Publication number: 20220105264Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: ApplicationFiled: December 15, 2021Publication date: April 7, 2022Applicant: ViaCyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Patent number: 11246979Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: GrantFiled: June 25, 2020Date of Patent: February 15, 2022Assignee: ViaCyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Publication number: 20200324043Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: ApplicationFiled: June 25, 2020Publication date: October 15, 2020Applicant: ViaCyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Patent number: 10722644Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: GrantFiled: November 20, 2014Date of Patent: July 28, 2020Assignee: Viacyte, Inc.Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Publication number: 20170266372Abstract: Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device.Type: ApplicationFiled: November 20, 2014Publication date: September 21, 2017Inventors: Chad Green, Laura Martinson, Erik Olson, Val Anthony Bellora, Leah Elliott, Richard Alexander Grant, Donald Koenig, Giacomo Strollo
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Patent number: 9638707Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: GrantFiled: November 21, 2016Date of Patent: May 2, 2017Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Publication number: 20170067925Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: ApplicationFiled: November 21, 2016Publication date: March 9, 2017Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Publication number: 20160374900Abstract: The present invention provides, in at least one embodiment, a loading device, system and method that loads aggregate cells into an encapsulation device for implanting into a patient. The loading system uses negative pressure from a low pressure pump in a closed system to improve safety and cell viability while allowing for even loading of the encapsulation device.Type: ApplicationFiled: August 22, 2016Publication date: December 29, 2016Inventors: Chad Green, Laura Martinson, Val Anthony Bellora, Richard Alexander Grant, Evert Kroon, Emmanuel Edward Baetge
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Patent number: 9527074Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: GrantFiled: July 21, 2016Date of Patent: December 27, 2016Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Publication number: 20160326573Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: ApplicationFiled: July 21, 2016Publication date: November 10, 2016Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Patent number: 9433557Abstract: The present invention provides, in at least one embodiment, a loading device, system and method that loads aggregate cells into an encapsulation device for implanting into a patient. The loading system uses negative pressure from a low pressure pump in a closed system to improve safety and cell viability while allowing for even loading of the encapsulation device.Type: GrantFiled: February 21, 2011Date of Patent: September 6, 2016Assignee: VIACYTE, INC.Inventors: Chad Green, Laura Martinson, Val Anthony Bellora, Richard Alexander Grant, Evert Kroon, Emmanuel Edward Baetge
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Patent number: 9409178Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: GrantFiled: April 21, 2015Date of Patent: August 9, 2016Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Publication number: 20150224506Abstract: Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.Type: ApplicationFiled: April 21, 2015Publication date: August 13, 2015Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Patent number: 9040303Abstract: An apparatus for measuring a volume of fluid includes at least one emitter configured to project a signal toward a predetermined position of a sample container, at least one receiver configured to receive the signal after the signal interacts with the sample container and a fluid transfer device in communication with the receiver and sample container. A change in the signal received by the receiver indicates when the fluid has dropped below the predetermined position. The apparatus determines a volume of fluid that the fluid transfer device has removed from the sample container when the receiver detects that the fluid has dropped below the predetermined position.Type: GrantFiled: March 18, 2013Date of Patent: May 26, 2015Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant
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Publication number: 20140014226Abstract: The present invention provides, in at least one embodiment, a loading device, system and method that loads aggregate cells into an encapsulation device for implanting into a patient. The loading system uses negative pressure from a low pressure pump in a closed system to improve safety and cell viability while allowing for even loading of the encapsulation device.Type: ApplicationFiled: February 21, 2011Publication date: January 16, 2014Inventors: Chad Green, Laura Martinson, Val Anthony Bellora, Richard Alexander Grant, Evert Kroon, Emmanuel Edward Baetge
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Patent number: 8431404Abstract: An apparatus for transfer of a liquid using a diaphragm that separates a working fluid volume from a working air volume and can controllably induce a change pressure to draw or expel a target fluid into a tube. The apparatus is particularly suitable for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier under the diaphraghm, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device.Type: GrantFiled: June 7, 2012Date of Patent: April 30, 2013Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Publication number: 20120270310Abstract: An apparatus for transfer of a liquid using a diaphragm that separates a working fluid volume from a working air volume and can controllably induce a change pressure to draw or expel a target fluid into a tube. The apparatus is particularly suitable for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier under the diaphraghm, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device.Type: ApplicationFiled: June 7, 2012Publication date: October 25, 2012Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris
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Patent number: 8211701Abstract: A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and/or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing.Type: GrantFiled: September 19, 2011Date of Patent: July 3, 2012Assignee: Argos Therapeutics, Inc.Inventors: Simon Jonathon Spence, Richard Alexander Grant, Timothy Doyle Peele, William Samuel Hunter, Ashraf F. Abdelmoteleb, David Thomas Kneen, Robert Alister Neil, Simon Harris