Abstract: A cardioplegia/air aspiration cannula assembly for delivering cardioplegic fluid to and for aspirating air from the aorta during surgery. The assembly includes a hub having a single needle portion. The needle portion has an inner cannula which extends through the hub and defines an inner lumen through which the cardioplegic fluid is injected. An outer cannula is coaxially positioned over the inner cannula and is diametrally spaced therefrom to define an outer lumen. A plurality of holes are formed in the sides of the outer cannula through which air can be aspirated. The outer lumen defined by the space between the inner and outer cannulae is in fluid communication with a passageway passing through a side branch of the hub which can be connected to a vacuum source.