Patents by Inventor Richard C. Egen

Richard C. Egen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080274515
    Abstract: Animal-free meninge fermentation media and process is developed based upon use of a chemically defined medium. To improve polysaccharide production, fed-batch fermentation is examined using different feed solutions and feeding strategies. A feed solution containing glucose, amino acids, and trace metal elements produces Group A polysaccharide at approximately 3 times the level observed with batch fermentation. This process is used successfully to produce polysaccharides of N. meningitidis serotypes A, C, Y and W-135 and is run reproducibly at the 20L scale and can be scaled to 400L or more.
    Type: Application
    Filed: July 8, 2008
    Publication date: November 6, 2008
    Inventors: Richard C. Egen, Lori Ann Fortin, Willie Wei Qiang Sun
  • Patent number: 7399615
    Abstract: Animal-free meninge fermentation media and process is developed based upon use of a chemically defined medium. To improve polysaccharide production, fed-batch fermentation is examined using different feed solutions and feeding strategies. A feed solution containing glucose, amino acids, and trace metal elements produces Group A polysaccharide at approximately 3 times the level observed with batch fermentation. This process is used successfully to produce polysaccharides of N. meningitidis serotypes A, C, Y and W-135 and is run reproducibly at the 20L scale and can be scaled to 400L or more.
    Type: Grant
    Filed: August 16, 2005
    Date of Patent: July 15, 2008
    Inventors: Richard C. Egen, Lori Ann Fortin, Willie Wei Qiang Sun
  • Patent number: 6933137
    Abstract: Animal-free meninge fermentation media and process is developed based upon use of a chemically defined medium. To improve polysaccharide production, fed-batch fermentation is examined using different feed solutions and feeding strategies. A feed solution containing glucose, amino acids, and trace metal elements produces Group A polysaccharide at approximately 3 times the level observed with batch fermentation. This process is used successfully to produce polysaccharides of N. meningitidis serotypes, A, C, Y and W-135 and is run reproducibly at the 20 L scale and can be scaled to 400 L or more.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: August 23, 2005
    Assignee: Aventis Pasteur
    Inventors: Richard C. Egen, Lori Ann Fortin, Willie Wei Qiang Sun
  • Publication number: 20040229319
    Abstract: Animal-free meninge fermentation media and process is developed based upon use of a chemically defined medium. To improve polysaccharide production, fed-batch fermentation is examined using different feed solutions and feeding strategies. A feed solution containing glucose, amino acids, and trace metal elements produces Group A polysaccharide at approximately 3 times the level observed with batch fermentation. This process is used successfully to produce polysaccharides of N. meningitidis serotypes A, C, Y and W-135 and is run reproducibly at the 20 L scale and can be scaled to 400 L or more.
    Type: Application
    Filed: May 16, 2003
    Publication date: November 18, 2004
    Inventors: Richard C. Egen, Lori Ann Fortin, Willie Wei Qiang Sun