Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 350 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 350b is formed on one side of the slot 350. A flat surface 354, which is formed in the stem 174, is spaced and extends angularly away from an opposite side of the slot 176 and from the extended side wall 350b to provide for direct and lateral dispensing of a cream 280 onto a tissue 242 of a patient.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 350 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 350b is formed on one side of the slot 350. A flat surface 354, which is formed in the stem 174, is spaced and extends angularly away from an opposite side of the slot 176 and from the extended side wall 350b to provide for direct and lateral dispensing of a cream 280 onto a tissue 242 of a patient.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 350 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 350b is formed on one side of the slot 350. A flat surface 354, which is formed in the stem 174, is spaced and extends angularly away from an opposite side of the slot 176 and from the extended side wall 350b to provide for direct and lateral dispensing of a cream 280 onto a tissue 242 of a patient.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 350 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 350b is formed on one side of the slot 350. A flat surface 354, which is formed in the stem 174, is spaced and extends angularly away from an opposite side of the slot 176 and from the extended side wall 350b to provide for direct and lateral dispensing of a cream 280 onto a tissue 242 of a patient.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 350 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 350b is formed on one side of the slot 350. A flat surface 354, which is formed in the stem 174, is spaced and extends angularly away from an opposite side of the slot 176 and from the extended side wall 350b to provide for direct and lateral dispensing of a cream 280 onto a tissue 242 of a patient.

Abstract: An autoinjector that automatically retracts a needle contained therein includes an injection assembly, having a plunger and a movable piston coupled to the plunger, a retraction assembly coupled to the injection assembly, and an end-of-dose visual indicator disposed within the retraction assembly. The retraction assembly includes an opaque section, a transparent or translucent section coupled to the opaque section, and a drug container having a hypodermic needle. The end-of-dose visual indicator is disposed within the retraction assembly such that the indicator moves upwardly from the opaque section of the retraction assembly to the transparent or translucent section of the retraction assembly upon full administration of a drug solution or medicine contained within the drug container. The end-of-dose visual indicator may be configured according to many preferred embodiments, among which may include a hollow cylinder, a split indicator ring, a co-extruded ring, and a multi-faceted polygonal cylinder.

Abstract: An autoinjector that automatically retracts a needle contained therein includes an injection assembly, having a plunger and a movable piston coupled to the plunger, a retraction assembly coupled to the injection assembly, and an end-of-dose visual indicator disposed within the retraction assembly. The retraction assembly includes an opaque section, a transparent or translucent section coupled to the opaque section, and a drug container having a hypodermic needle. The end-of-dose visual indicator is disposed within the retraction assembly such that the indicator moves upwardly from the opaque section of the retraction assembly to the transparent or translucent section of the retraction assembly upon full administration of a drug solution or medicine contained within the drug container. The end-of-dose visual indicator may be configured according to many preferred embodiments, among which may include a hollow cylinder, a split indicator ring, a co-extruded ring, and a multi-faceted polygonal cylinder.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 176 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 176b is formed on one side of the slot 176. A flat surface 276 is formed in the stem 174 and extends angularly away from an opposite side of the slot 176 and from the extended side wall 176b to provide a wide slot opening at an external surface 195 of the stem for dispensing a cream from the opening. A trough-like cleft 306 can be formed in the external surface 195 of a solid portion of the stem 174, distally of the slot 176, to provide an axially-extended path for the cream being dispensed through the slot.

Abstract: A device 560, for administering multiple single doses of a medicated cream, includes a cartridge 562 having a barrel 564 for containing the cream, a plunger 608 for moving the cream from within the cartridge, and a stem 610 for moving the plunger within the cartridge. A carrier 612 is formed with a cartridge-receiving nest 712 for receiving the barrel 564. A plurality of spaced, transaxial grooves 726, 728, 730 and 732 are formed in the carrier 612 for receiving a flange 572 of the cartridge 562 during the dispensing of multiple, successive, single doses of the cream. The carrier 612 is formed with a pair of resilient ears 750 and 752 and a passage 738 for removably retaining the stem 610 with the carrier while allowing axial movement of the stem.

Abstract: Applicators 470,472, 474, and 475 include a body with a stem 174 having an axially-formed slot delivery passage 200. Slot 176 is formed transaxially through stem 174 in communication with slot delivery passage 200. Proximal and distal transition surfaces 176e and 176g are formed at axial ends of slot 176. Stem 174 of applicator 470 is tapered axially distally inward. Flat surface 276 may be formed adjacent slot 176. The body is formed with flange 172 having a seat for receipt of a vagina or anus of a patient. Stem 174 of the applicator 474 is curved away from a normal axis of the body. Stem-like proximal section 174a of the body of applicator 475 is curved away from the normal axis of the body, with a distal end of the section integrally joined with a proximal end of the straight stem 174.

Abstract: An applicator 270 includes a stem 174 having an axially-formed slot delivery passage 200. A slot 176 is formed transaxially through the stem 174 and is in communication with the slot delivery passage 200. An extended side wall 176b is formed on one side of the slot 176. A flat surface 276 is formed in the stem 174 and extends angularly away from an opposite side of the slot 176 and from the extended side wall 176b to provide a wide slot opening at an external surface 195 of the stem for dispensing a cream from the opening. A trough-like cleft 306 can be formed in the external surface 195 of a solid portion of the stem 174, distally of the slot 176, to provide an axially-extended path for the cream being dispensed through the slot.

Abstract: An automatic injection and retraction device having a longitudinal axis is provided that includes an injection assembly, a retraction assembly, and a pre-filled syringe cartridge. The injection assembly has an activation-prevention feature moveable between an on position and an off position. The retraction assembly has a needle guard that is removable in a direction along the longitudinal axis upon application of a removal force. The pre-filled syringe cartridge has a hypodermic needle with a needle sheath thereon. The retraction and injection assemblies are secured to one another so that the pre-filled syringe cartridge is in the retraction assembly with the needle sheath secured to the needle guard. The retraction and injection assemblies are configured so that, upon application of a twisting torque to the injection and retraction assemblies, the activation-prevention feature moves from the on position to the off position simultaneous with applying the removal force to the needle guard.

Abstract: A device 560, for administering multiple single doses of a medicated cream, includes a cartridge 562 having a barrel 564 for containing the cream, a plunger 608 for moving the cream from within the cartridge, and a stem 610 for moving the plunger within the cartridge. A carrier 612 is formed with a cartridge-receiving nest 712 for receiving the barrel 564. A plurality of spaced, transaxial grooves 726, 728, 730 and 732 are formed in the carrier 612 for receiving a flange 572 of the cartridge 562 during the dispensing of multiple, successive, single doses of the cream. The carrier 612 is formed with a pair of resilient ears 750 and 752 and a passage 738 for removably retaining the stem 610 with the carrier while allowing axial movement of the stem.

Abstract: An automatic mixing and injecting apparatus comprises a syringe assembly (400) within a housing (100). The syringe assembly (400) has a chamber (425) for holding a liquid, which can be a liquid medicine or a solvent. A second chamber (460) may hold a dry medicine. The second chamber (460) is releasably sealed with respect to the first chamber (425). A spring-operated plunger (300) forces liquid from the first chamber (425) and causes the releasable seal (430) to disengage when the needle (540) has entered the recipient. At this time, the liquid flows through the second chamber (460) and dissolves any dry medicine in that chamber (460). A releasable coupling (340) disengages the plunger (300) from the driver spring (500) and allows the plunger (300), syringe assembly (400), and needle (540) to retract under the urging of a return spring (505).

Abstract: A method of applying a medicinal substance onto an area within a patient's body cavity includes providing an applicator formed by six integral sections. A proximal section is formed with an entry passage. An axial intermediate passage of the applicator extends from the entry passage through a flange section and a passage section. A slot section has a slot delivery passage communicating with the axial intermediate passage, and at least one axially-elongated slot therethrough. A solid section extends from the slot section, and a dome section extends to an end of the applicator. The method further includes locating the slot delivery passage adjacent the area within the cavity, forming a substance mass externally of the cavity, moving the mass into the slot delivery passage, and moving at least a portion of the substance onto the area.

Abstract: A device 560, for administering multiple single doses of a medicated cream, includes a cartridge 562 having a barrel 564 for containing the cream, a plunger 608 for moving the cream from within the cartridge, and a stem 610 for moving the plunger within the cartridge. A carrier 612 is formed with a cartridge-receiving nest 712 for receiving the barrel 564. A plurality of spaced, transaxial grooves 726, 728, 730 and 732 are formed in the carrier 612 for receiving a flange 572 of the cartridge 562 during the dispensing of multiple, successive, single doses of the cream. The carrier 612 is formed with a pair of resilient ears 750 and 752 and a passage 738 for removably retaining the stem 610 with the carrier while allowing axial movement of the stem.

Abstract: An automatic mixing and injecting apparatus comprises a syringe assembly (400) within a housing (100). The syringe assembly (400) has a chamber (425) for holding a liquid, which can be a liquid medicine or a solvent. A second chamber (460) may hold a dry medicine. The second chamber (460) is releasably sealed with respect to the first chamber (425). A spring-operated plunger (300) forces liquid from the first chamber (425) and causes the releasable seal (430) to disengage when the needle (540) has entered the recipient. At this time, the liquid flows through the second chamber (460) and dissolves any dry medicine in that chamber (460). A releasable coupling (340) disengages the plunger (300) from the driver spring (500) and allows the plunger (300), syringe assembly (400), and needle (540) to retract under the urging of a return spring (505).

Abstract: A device 560, for administering multiple single doses of a medicated cream, includes a cartridge 562 having a barrel 564 for containing the cream, a plunger 608 for moving the cream from within the cartridge, and a stem 610 for moving the plunger within the cartridge. A carrier 612 is formed with a cartridge-receiving nest 712 for receiving the barrel 564. A plurality of spaced, transaxial grooves 726, 728, 730 and 732 are formed in the carrier 612 for receiving a flange 572 of the cartridge 562 during the dispensing of multiple, successive, single doses of the cream. The carrier 612 is formed with a pair of resilient ears 750 and 752 and a passage 738 for removably retaining the stem 610 with the carrier while allowing axial movement of the stem.

Abstract: A device 60, for administering medicated cream, includes a cartridge 62 for containing the cream, a plunger head 100 for moving the cream from within the cartridge, and a stem 106 for moving the plunger head within the cartridge. The plunger head 100 includes a tapered receptor opening 148 for reception of a tapered stem structure 114. A rib 156 is formed on the cartridge 62, and a plurality of ribs 164 are formed on the stem 106, cooperate to provide tactile notification to a patient-user that measured doses of the cream have been administered.

Abstract: An automatic mixing and injecting apparatus comprises a syringe assembly within a housing. The syringe assembly has a chamber for holding a liquid, which can be a liquid medicine or a solvent. A second chamber may hold a dry medicine. The second chamber is releasably sealed with respect to the first chamber. A spring-operated plunger forces liquid from the first chamber and causes the releasable seal to disengage when the needle has entered the recipient. At this time, the liquid flows through the second chamber and dissolves any dry medicine in that chamber. A releasable coupling disengages the plunger from the driver spring and allows the plunger, syringe, and needle to retract under the urging of a return spring.