Abstract: Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods.

Abstract: The process for manufacturing unsaturated mononitriles, such as acrylonitrile and methacrylonitrile, has been modified to add a partially condensed quench effluent stripper column to remove high boiling organic compounds from the reactor effluent prior to introduction into the extractive distillation recovery column. The high boiling organic compounds are preferably removed after the ammonia in the reactor effluent has been neutralized and the neutralization products have been removed. The targeted high boiling organic compounds are associated with fouling in the recovery section of the plant.

Abstract: Acrolein is removed from a process stream such as a process stream generated in the manufacture of acrylonitrile. The process includes reacting the acrolein with a compound containing a reactable thiol or hydroxyl moiety in the presence of an acid catalyst. The present process provides for a refined process stream that contains no more than 5 ppm by weight unreacted acrolein.

Abstract: Acrolein is removed from a process stream such as a process stream generated in the manufacture of acrylonitrile. The process includes reacting the acrolein with a compound containing a reactable thiol or hydroxyl moiety in the presence of an acid catalyst. The present process provides for a refined process stream that contains no more than 5 ppm by weight unreacted acrolein.

Abstract: Acrolein is removed from a process stream such as a process stream generated in the manufacture of acrylonitrile. The process includes reacting the acrolein with a compound containing a reactable thiol or hydroxyl moiety in the presence of an acid catalyst. The present process provides for a refined process stream that contains no more than 5 ppm by weight unreacted acrolein.

Abstract: An overhead stream from the quench system in a process for purifying acrylonitrile is condensed and recycled directly to the quench system as part of the quench liquid. The stream can be condensed in a column or in a partial condenser.

Abstract: A page wide piezoelectric ink jet print engine and a method of manufacturing the same. The page wide ink jet print engine includes lower and upper body parts, each formed from piezoelectric material and having a plurality of generally parallel, spaced projections. Lower side surfaces of the projections of the lower body part are conductively mounted to corresponding bottom side surfaces of the projections of the upper body part to define a plurality of generally parallel, axially extending ink-carrying channels from which ink may be ejected.

Abstract: A page wide piezoelectric ink jet print engine and a method of manufacturing the same. The page wide ink jet print engine includes lower and upper body parts, each formed from piezoelectric material and having a plurality of generally parallel, spaced projections. Lower side surfaces of the projections of the lower body part are conductively mounted to corresponding bottom side surfaces of the projections of the upper body part to define a plurality of generally parallel, axially extending ink-carrying channels from which ink may be ejected.

Abstract: Disclosed is a method of manufacturing an ink jet printhead comprising the steps of: (1) coating a substantially flat lower surface of an upper piezoelectric member with a first conductive coating, (2) coating a substantially flat upper surface of a lower piezoelectric member with a second conductive coating, (3) depositing a conductive metal over the first conductive coating, (4) forming a first elongated indentation in the lower surface, the first indentation extending through the first coating and into the upper member, (5) joining the metal with the second conductive coating by placing the upper piezoelectric member over the lower piezoelectric member, (6) inducing a current in the metal with an electromagnetic field having a specified frequency to thereby melt the metal and (7) cooling the metal, the metal electrically and mechanically joining the first coating to the second coating, the first indentation and the upper surface thereby forming the channel, the channel capable of containing ink and capable

Abstract: A backup software program is installed in an isolated portion in the memory of at least one of redundant computers. The backup program performs basically the same functions as the prime program but is dissimilarly programmed to prevent a common software error. Switchover to the backup program occurs either automatically in response to monitors, or manually by the operator (i.e. pilot) when he detects an anomaly.

Abstract: A backup software program is installed in an isolated portion in the memory of at least one of redundant computers. The backup program performs basically the same functions as the prime program but is dissimilarly programmed to prevent a common software error. Switchover to the backup program occurs either automatically in response to monitors, or manually by the operator (i.e. pilot) when he detects an anomaly.

Abstract: Collective stick inputs are provided (18) to a high pass filter (24) when collective stick reversals in excess of a threshold collective authority rate (15%/sec) and in excess of a threshold frequency (3 stick reversals per second) are sensed. The output of the high pass filter (24) is scaled (26) and subtracted (14) from the collective inputs so as to effectively cancel the threshold stick reversals. Otherwise, if no stick reversals in excess of the threshold collective authority rate are sensed for a threshold time interval (5 seconds), the collective stick inputs are not provided to the high pass filter.

Abstract: A backup software program is installed in an isolated portion in the memory of at least one of redundant computers. The backup program performs basically the same functions as the prime program but is dissimilarly programmed to prevent a common software error. Switchover to the backup program occurs either autoamtically in response to monitors, or manually by the operator (i.e. pilot) when he detects an anomaly.

Abstract: An aircraft automatic flight control system (AFCS) includes a pair of fast, limited authority inner loop actuators responsive to signals indicative of aircraft attitude or other flight parameters such as airspeed, the inner loop being recentered by an outer loop actuator responsive to attitude or other aircraft parameter-indicating signals (54,55). Commands applied to the outer loop are applied in a lagged fashion in opposite direction so as to drive the inner loop actuators back toward the center of their authority. The rate of response of the outer loop is adaptive in response to magnitude of inner loop input (101, FIG. 2). A pitch bias command is provided to the inner loop as a function of airspeed multiplied inversely with collective pitch, and as a function of the rate of change of collective stick position, so as to provide a positive static pitch trim gradient and decouple collective pitch from the longitudinal cyclic pitch channel.

Abstract: Method and apparatus are provided for determining the formation pressure. The magnitude of formation pressure may be derived as a function of changes in bottomhole pressure following swabbing the borehole to draw formation fluids into the borehole, monitoring the borehole for influx of formation fluids, determining the reduced pressure due to swabbing, repeating the swabbing and monitoring steps until an influx of formation fluids is detected thereby determining the pressure of the formation.

Abstract: An oscillatory-failure monitor (101) compares a parameter of a plurality of signals (A, B) within a tolerance (TOL) to determine agreement or disparity among the signals. Each discrete miscompare occurrence (i.e., singular disparity following full agreement) is counted by incrementing (27; 54) a counter (OSCCT; CNTR). The counter is decremented (32; 62) whenever the signals compare for a predetermined time interval (29; 47). An oscillatory-failure is declared when the counter increments to a threshold (28, 21; 57, 58, 60). Both digital (FIG. 1) and dedicated hardware (FIG. 4) embodiments are disclosed.

Abstract: A torque limiting altitude hold system for a helicopter engages torque limiting (56, 203) when excessive torque is anticipated (138, 202) as determined by the summation of present torque and torque rate times a reference value (126, 194) exceeds maximum torque with torque limiting engaged, altitude commands are faded out (42, 189) and torque commands are faded in (44, 190) and the collective command integrator is switched from altitude to torque (48, 54; 181, 185), torque limiting is ended in response to negative altitude commands or anticipated desired altitude signal (96, 150, 152; 205, 206); the anticipated desired altitude is determined by subtracting from the altitude error a time function of the altitude rate (84, 90; 193), torque limiting is not allowed to reengage for two seconds after disengaging (144, 204) nor within three seconds after reaching desired altitude during an automatic descent (146, 207), the system provides smooth transitions from altitude control to torque control, without oscillation

Abstract: A maneuver force gradient system causes a helicopter, that otherwise tends to pitch up in a banked turn, to pitch nose-down. A command signal (25) is provided as a function of the roll angle to operate the longitudinal trim actuator (27) which automatically moves the cyclic control (50) resiliently (28) forward to push the nose down. The pilot must consequently pull back on the cyclic control (50) to achieve a desired pitch attitude, thereby establishing a longitudinal positive maneuver-force gradient. The system is operable only when the pilot initiates a roll (33, 38, 50, 51) and the roll angle equals or exceeds 30.degree. (30, 33, 36, 37). Both analog (FIG. 1) and digital (FIG. 2) embodiments are disclosed, and the invention may be practiced in association with an AFCS (101) having the longitudinal trim actuator (27) and resilient linkage (28).

Abstract: An adjustable mounting assembly has a slot through the control arm of a steerable wheel suspension system in which a threaded stud of a ball joint extends. Nuts threadably engage the stud and clamp the control arm in place to fix the spindle in an adjusted position. The nuts are longitudinally adjusted along the stud to preload the ball joint to a desired amount.

Abstract: An automatic flight control system, for an aircraft having a roll attitude retention outer loop actuator (29), a roll stability inner loop actuator (25) and a control stick (26) for positioning control surfaces of the aircraft to control its roll attitude, includes means (54, 55) to provide a roll error signal (56) indicative of the deviation in roll attitude from a desired roll attitude. The roll attitude retention outer loop actuator (29) is controlled by a proportional (61) and integral (62) function of the roll error when force is not applied to the stick, but only as a proportional function when force is applied to the stick (48, 49, 51, 62). The roll stability inner loop actuator is controlled by a washed out (72) proportional (64) function of the roll error signal to provide short-term roll retention at roll attitudes established by the control stick during turns against trim. Sensing force on the stick (51, 95, FIG.