Patents by Inventor Richard Dickinson Chambers

Richard Dickinson Chambers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7541008
    Abstract: A reactor for carrying out a reaction between at least two fluids comprises a reactor plate (20) with a plurality of grooves or through slots (22) in which the fluids mix and react and a separable overlying reservoir plate (2) for supplying the fluids to slots (22) from reservoirs (4, 6) via slots (10) a, (10) b, with a collecting conduit or reservoir (8) and slots (10) c for the product of the reaction. Reservoir plate (2) may lie between two reactor plates, or a single reactor plate (20) may lie between two reservoir plates. Third or further reservoirs may or may not be spaced from the second reservoir (6) depending on whether more than two fluids need to be present simultaneously, or whether a second reaction is required after the first two fluids have had time to react. Means may be provided for controlling the pressure in slots (22), the pressure differential (and flow rate) along slot (22), and/or the temperature in the reservoirs (4, 6) or slots (22).
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: June 2, 2009
    Assignee: University of Durham of University Office
    Inventors: Richard Dickinson Chambers, Darren Holling, Graham Sandford
  • Patent number: 6747178
    Abstract: According to the present invention there is provided a method of carrying out a chemical reaction between at least two fluids, the method comprising providing respective flow paths for the at least two fluids, said flow paths communicating with each other in a region in which the at least two fluids may contact each other, and flowing the at least two fluids along said flow paths such that in said region the at least two fluids contact each other and a chemical reaction occurs between them, said region having a width perpendicular to the direction of flow in the range 10-10,000 micrometers. It has been found that using a so-called “microreactor”, that is a reactor having dimensions perpendicular to the flow direction of less than 10,000 micrometers, according to the present method, improved control over a fluid chemical reaction can be achieved, which can result in significant improvements in reaction product yield and/or purity, as well as other benefits.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: June 8, 2004
    Assignee: British Nuclear Fuels plc
    Inventors: Paul Harston, Malcolm John Atherton, Robert G. Holmes, Richard Dickinson Chambers, Robert Spink
  • Patent number: 6441232
    Abstract: There is provided a method of selectively replacing a carbon-hydrogen bond at an unactivated saturated sp3 hybridised carbon atom in an organic compound by a carbon-nitrogen bond, the method comprising reacting the compound with a fluorinating agent in a solvent reaction medium comprising a nitrile compound and providing a Lewis acid whereby the carbon-hydrogen bond is replaced by a carbon-nitrogen bond. Advantageously, the reaction may be performed in one stage and/or in one vessel. Advantageously, the method may be carried out at or just below ambient or room temperature.
    Type: Grant
    Filed: January 1, 2002
    Date of Patent: August 27, 2002
    Assignee: F2 Chemicals Ltd.
    Inventors: Richard Dickinson Chambers, Mandy Parsons, Graham Sandford
  • Patent number: 6388133
    Abstract: A process for the preparation of an N,N-disubstituted-2-fluoro-1,3-ketoamide having the formula RCO.CFR′CONR2″ comprises treating an N,N-disubstituted-1,3-ketoamide having the formula RCO.CHR′CONR2″ with elemental fluorine. The groups R, R′ and R″ are independently selected from alkyl, aryl, substituted aryl, cycloalkyl, and substituted cycloalkyl. The group R′ may also be nitro or chlorine.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: May 14, 2002
    Assignee: F2 Chemicals Limited
    Inventors: Richard Dickinson Chambers, John Hutchinson, Julie Thomson
  • Patent number: 6300511
    Abstract: The present invention provides a method of substituting a carbonyl compound with fluorine at the &agr;-position, comprising reaching the carbonyl compound with a fluorinating present of a metal-containing catalyst. The reaction results in replacement of a hydrogen atom by fluorine. The catalyst, which is used in a catalytically effective amount, is preferably a transition metal. In one class of methods the catalyst is a transition metal compound. In another class of methods, the catalyst is an elemental metal, in which case the carbonyl compound has an activating group attached to the carbon atom which is substituted by fluorine.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: October 9, 2001
    Assignee: F2 Chemicals Limited
    Inventors: Richard Dickinson Chambers, John Hutchinson, John Stewart Moilliet
  • Patent number: 6255518
    Abstract: A method for the preparation of a fluorinated Phosphonate having the formula (RO)2PO CFR′R″ comprises treating a phosphonate of the formula (RO)2PO CHR′R″, or a metal salt thereof, with fluorine. R is an alkyl group R′ is hydrogen or alkyl and R″ is hydrogen, alkyl or another group.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: July 3, 2001
    Assignee: F2 Chemicals, Limited
    Inventors: Richard Dickinson Chambers, John Hutchinson
  • Patent number: 6031139
    Abstract: The use of polar organic solvent as the solvent in the direct fluorination, to make an .alpha.-fluoroketone, of an enol ester or enol trialkylsilyl ether of a compound containing a tautomerisable ketone group, the solvent being relatively inert to fluorine and one in which the enol ester or enol trialkylsilyl ether is relatively stable to hydrolysis. Preferably the solvent is anhydrous, e.g. anhydrous acetonitrile. Alternatively commercial formic acid containing 3% water may be used with a said enol ester.
    Type: Grant
    Filed: February 5, 1998
    Date of Patent: February 29, 2000
    Assignee: F2 Chemicals Limited
    Inventors: John Hutchinson, Richard Dickinson Chambers
  • Patent number: 5900502
    Abstract: According to the present invention there is provided a process for the selective introduction of one or more fluorine atoms into a disubstituted aromatic compound in an acid medium with fluorine gas characterized in that the acid medium has a dielectric constant of at least 20 and a pH of less than 3. The present process provides a cost effective means of selectively introducing one or more fluorine atoms into an aromatic compound in good overall yield.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: May 4, 1999
    Assignee: BNFL Fluorochemicals Limited
    Inventors: Christopher John Skinner, John Hutchinson, Julie Thomson, Richard Dickinson Chambers
  • Patent number: 5859255
    Abstract: A method of fluorinating a heterocyclic organic compound comprises the step of reacting a heterocyclic compound with elemental fluorine in the presence of another halogen. The reaction may be conducted in the presence of a base.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: January 12, 1999
    Assignee: F2 Chemicals Ltd.
    Inventors: Richard Dickinson Chambers, Graham Sandford
  • Patent number: 5847198
    Abstract: A process for the preparation of an ester, especially fluorinated esters R.sub.1 O.OC--CHR.sub.2 --CO.OR.sub.3, R.sub.1 and R.sub.3 are each independently selected from alkyl, cycloalkyl and aryl. R.sub.2 is selected from hydrogen, alkyl, cycloalkyl. The method includes the steps of covering a corresponding compound of formula 2: R.sub.1 O.OC--CHR.sub.2 --CO.OR.sub.3 in the presence of a base, of salt of a compound of formula 2, into corresponding compound of formula 1 by the reaction of elemental fluorine.
    Type: Grant
    Filed: December 12, 1997
    Date of Patent: December 8, 1998
    Assignee: F2 Chemicals Limited
    Inventors: Richard Dickinson Chambers, John Hutchinson, Julie Thomson
  • Patent number: 5789580
    Abstract: A process for the preparation of a selectively fluorinated organic compound, which process includes reaction of a precursor of said organic compound, the precursor containing at least one Group VI element selected from sulfur, selenium and tellurium, with a fluorinating agent and another halogenating agent and characterized in that the fluorinating agent is elemental fluorine.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: August 4, 1998
    Assignee: British Nuclear Fuels plc
    Inventors: Richard Dickinson Chambers, Graham Sandford
  • Patent number: 5734073
    Abstract: A method of halogenating an aromatic compound which comprises the steps of reacting an halogenating agent with the aromatic compound in the presence of fluorine and an acid, wherein the halogenating agent is at least one of an iodinating agent, a brominating agent and an chlorinating agent.
    Type: Grant
    Filed: April 18, 1996
    Date of Patent: March 31, 1998
    Assignee: BNFL Fluorochemicals Ltd
    Inventors: Richard Dickinson Chambers, Christopher John Skinner, Malcolm John Atherton, John Stewart Moilliet
  • Patent number: 5705668
    Abstract: New phosphazene derivatives, fully substituted by aromatic groups and perfluoropolyethereal chains, are utilized as stabilizers for oils and greases based on perfluoropolyethers. Such derivatives inhibit the degradation process affecting the perfluoropolyethereal chains when these are subjected to high temperatures in an oxidizing atmosphere and in the presence of metals, such as for example aluminium, titanium, vanadium and their alloys, or steels.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: January 6, 1998
    Assignee: Ausimont S.p.A.
    Inventors: Paolo Odello, Walter Navarrini, Richard Dickinson Chambers, Costante Corti
  • Patent number: 5672767
    Abstract: A process for the preparation of a perfluoropolyether having a general formula: ##STR1## as defined hereinbefore, which process includes the direct fluorination with elemental fluorine of a polyether having a general formula: ##STR2## as defined hereinbefore, wherein the fluorination is carried out in the presence of a solvent which is an ether having at least one substituent R.sub.F, wherein R.sub.F is a fluorinated hydrocarbon group. The said solvent ether is preferably a fluorinated volatile ether. The said solvent ether preferably has at least two groups R.sub.F which may be the same or different groups. Each group R.sub.F preferably has from two to four carbon atoms and at least two fluorine atoms. The said solvent ether may be an alicyclic ether having from 3 to 5 carbon atoms in its alicyclic ring.
    Type: Grant
    Filed: July 5, 1996
    Date of Patent: September 30, 1997
    Assignee: BNFL Fluorochemicals Ltd.
    Inventors: Richard Dickinson Chambers, Andrew Keith Joel