Abstract: The present invention includes methods of selecting cases in which to pack items in an item order and selecting the sequence and configuration of placement of items into the selected cases. One such method includes examining an order comprising a list of items to be packed, determining the cases available for packing, determining the minimum number of cases required for packing the items in the list of items to be packed, selecting a case to be packed with one or more of the items in the list of items to be packed, wherein said selecting a case comprises determining a desired average volume per case and selecting the smallest of the cases available to be packed that comprises a volume in excess of the average volume per case, and determining the configuration of placement in the case to be packed of items in the list of items to be packed. Such steps may be repeated until all items in the item list are selected and configured for packing.