Patents by Inventor Richard Gammans

Richard Gammans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer therapy
    Patent number: 8765729
    Abstract: The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide dismutase (SOD)) as the active agent or as a chemo- and/or radio-protectant. The invention also relates to compounds and compositions suitable for use in such a method.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: July 1, 2014
    Assignees: Aeolus Sciences, Inc., Duke University, National Jewish Medical and Research Center
    Inventors: James D. Crapo, Brian J. Day, Ines Batinic-Haberle, Richard Gammans, Zeljko Vusjaskovic
  • Oxidant scavengers for treatment of type I diabetes or type II diabetes
    Patent number: 8470808
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: June 25, 2013
    Inventors: Jon D. Piganelli, Kathryn Haskins, Sonia C. Flores, James D. Crapo, Brian J. Day, Ronald G. Gill, Richard Gammans, Manisha Patel
  • Oxidant Scavengers for Treatment of Diabetes or Use in Transplantation or Induction of Immune Tolerance
    Publication number: 20110105452
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: November 8, 2010
    Publication date: May 5, 2011
    Applicants: Aeolus Sciences, Inc., National Jewish Medical and Research Center, University of Colorado Health Sciences Center
    Inventors: Jon D. Piganelli, Kathryn Haskins, Sonia C. Flores, James D. Crapo, Brian J. day, Ronald G. Gill, Richard Gammans, Manisha Patel
  • OXIDANT SCAVENGERS FOR TREATMENT OF DIABETES OR USE IN TRANSPLANTATION OR INDUCTION OF IMMUNE TOLERANCE
    Publication number: 20080085883
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: September 19, 2007
    Publication date: April 10, 2008
    Applicants: AEOLUS SCIENCES, INC., National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Children's Hospital of Pittsburgh
    Inventors: Jon PIGANELLI, Kathryn HASKINS, Sonia FLORES, James CRAPO, Brian DAY, Ronald GILL, Richard GAMMANS, Manisha PATEL
  • METHOD OF TREATMENT OR PROPHYLAXIS OF DEPRESSION
    Publication number: 20080064758
    Abstract: The invention concerns a method of treatment or prophylaxis of depression by administering a phenylethanolaminocyclohexylphenyl compound of a general formula (I) in which R1 represents hydrogen or halogen; R2 represents hydrogen, hydroxy, lower alkoxy, lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups, lower alkoxy substituted with lower alkylaminocarbonyl which may be substituted with lower alkoxy, lower alkoxy substituted with cyclic aminocarbonyl of 4 to 6 carbon atoms, lower alkoxycarbonyl or carboxy; R3 represents hydrogen, hydroxy, lower alkoxy or lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups; R2 and R3 may be bonded to each other to form methylenedioxy substituted with carboxy or lower alkoxycarbonyl; and m and n are 0 or 1, and their pharmacologically acceptable metabolites or salts, which have selective stimulating activity and binding affinity for ?3 adrenergic receptors.
    Type: Application
    Filed: August 21, 2007
    Publication date: March 13, 2008
    Inventors: Kenneth Locke, Richard Gammans
  • CANCER THERAPY
    Publication number: 20070149498
    Abstract: The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide dismutase (SOD)) as the active agent or as a chemo- and/or radio-protectant. The invention also relates to compounds and compositions suitable for use in such a method.
    Type: Application
    Filed: November 9, 2006
    Publication date: June 28, 2007
    Applicants: Aeolus Sciences, Inc., National Jewish Medical and Research Center, Duke University
    Inventors: James Crapo, Brian Day, Ines Batinic-Haberle, Richard Gammans, Zeljko Vusjaskovic
  • Cancer therapy
    Publication number: 20030050297
    Abstract: The present invention relates, in general, to cancer therapy, and, in particular, to a method of preventing or treating cancer using low molecular weight antioxidants (e.g., mimetics of superoxide dismutase (SOD)) as the active agent or as a chemo- and/or radio-protectant. The invention also relates to compounds and compositions suitable for use in such a method.
    Type: Application
    Filed: January 22, 2002
    Publication date: March 13, 2003
    Inventors: James D. Crapo, Brian J. Day, Ines Batinic-Haberle, Richard Gammans, Zeljko Vujaskovic
  • Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
    Publication number: 20030032634
    Abstract: The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method of protecting and/or enhancing viability of cells/tissues/organs during isolation (harvesting), preservation, expansion and/or transplantation. In yet another embodiment, the present invention relates to a method of inducing immune tolerance. The invention also relates to compounds and compositions suitable for use in such methods.
    Type: Application
    Filed: June 3, 2002
    Publication date: February 13, 2003
    Inventors: Jon D. Piganelli, Kathryn Haskins, Sonia C. Flores, James D. Crapo, Brian J. Day, Ronald G. Gill, Richard Gammans, Manisha Patel
  • Treatment of sleep disorders
    Patent number: 5116852
    Abstract: Certain antidepressants have been found to alleviate sleeping disorders associated with less than normal REM sleep.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: May 26, 1992
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Richard Gammans