Abstract: Novel kits and methods for recovering nucleic acids and proteins from a biological sample having the steps of mixing a biological sample with a nucleic acid binding solution and contacting the mixture with a first porous silica compound configured to reversibly bind a nucleic acid are disclosed herein. The fluid remainder of the mixture is gathered for protein extraction. The first silica compound is contacted with a nucleic acid elution solution which causes a majority of the nucleic acid bound to the first porous silica compound to unbind and enter the solution phase. The solution is collected, which contains isolated nucleic acid. The fluid gathered for protein extraction is mixed with a protein binding solution and contacted with a protein binding porous silica compound configured to reversibly bind a protein. The fluid remainder is separated from the protein binding porous silica compound.

Abstract: A novel method for recovering nucleic acids and proteins from a biological sample having the steps of mixing a biological sample with a nucleic acid binding solution and contacting the mixture with a first porous silica compound configured to reversibly bind a nucleic acid. The fluid remainder of the mixture is gathered for protein extraction. The first silica compound is contacted with a nucleic acid elution solution which causes a majority of the nucleic acid bound to the first porous silica compound to unbind and enter the solution phase. The solution is collected, which contains isolated nucleic acid. The fluid gathered for protein extraction is mixed with a protein binding solution and contacted with a protein binding porous silica compound configured to reversibly bind a protein. The fluid remainder is separated from the protein binding porous silica compound.