Patents by Inventor Richard J. Whitley

Richard J. Whitley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of tumors with genetically engineered herpes virus
    Patent number: 8772261
    Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: July 8, 2014
    Assignee: Arch Development Corporation
    Inventors: Ralph R. Weichselbaum, Bernard Roizman, Richard J. Whitley
  • Herpes simplex virus expressing foreign genes and method for treating cancers therewith
    Patent number: 8420071
    Abstract: An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including a HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: April 16, 2013
    Assignee: The UAB Research Foundation
    Inventors: Richard J. Whitley, James MacDowell Markert, George Yancey Gillespie, Jacqueline Nuss Parker
  • Treatment of tumors with genetically engineered herpes virus
    Patent number: 8318691
    Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: November 27, 2012
    Assignees: Arch Development Corporation, UAB Research Foundation
    Inventors: Ralph R. Weichselbaum, Bernard Roizman, Richard J. Whitley
  • Treatment of tumors with genetically engineered herpes virus
    Publication number: 20110002890
    Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
    Type: Application
    Filed: June 7, 2010
    Publication date: January 6, 2011
    Applicants: UAB RESEARCH FOUNDATION
    Inventors: Ralph R. Weichselbaum, Bernard Roizman, Richard J. Whitley
  • Recombinant herpes simplex virus useful for treating neoplastic disease
    Patent number: 7744899
    Abstract: Recombinant herpes simplex viruses comprising DNA encoding cytokines and methods for treating neoplastic diseases using the inventive recombinant viruses are disclosed.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: June 29, 2010
    Assignees: The University of Chicago, UAB Research Foundation
    Inventors: Richard J. Whitley, Bernard Roizman
  • HERPES SIMPLEX VIRUS EXPRESSING FOREIGN GENES AND METHOD FOR TREATING CANCERS THEREWITH
    Publication number: 20090186003
    Abstract: An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including a HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
    Type: Application
    Filed: September 19, 2008
    Publication date: July 23, 2009
    Inventors: Richard J. Whitley, James MacDowell Markert, George Yancey Gillespie, Jacqueline Nuess Parker
  • Herpes simplex virus expressing foreign genes and method for treating cancers therewith
    Publication number: 20040258667
    Abstract: An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including a HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
    Type: Application
    Filed: July 8, 2004
    Publication date: December 23, 2004
    Inventors: Richard J. Whitley, James MacDowell Markert, George Yancey Gillespie, Jacqueline Ness Parker
  • Herpes simplex virus expressing foreign genes and method for treating cancers therewith
    Patent number: 6764675
    Abstract: An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including an HSV vector having a nucleic acid sequence encoding an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: July 20, 2004
    Assignee: The UAB Research Foundation
    Inventors: Richard J. Whitley, James MacDowell Markert, George Yancey Gillespie, Jacqueline Ness Parker
  • Treatment of tumors with genetically engineered herpes virus
    Publication number: 20030207829
    Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
    Type: Application
    Filed: September 26, 2001
    Publication date: November 6, 2003
    Applicants: Arch Development Corporation, UAB Research Foundation
    Inventors: Ralph Weichselbaum, Bernard Roizman, Richard J. Whitley
  • Treatment of tumors with genetically engineered herpes virus
    Publication number: 20020019362
    Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.
    Type: Application
    Filed: September 26, 2001
    Publication date: February 14, 2002
    Applicant: Arch Development Corporation
    Inventors: Ralph Weichselbaum, Bernard Roizman, Richard J. Whitley