Abstract: A high throughput biological sample processing system includes a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system. The system further includes a sample dispensing module, a reagent dispensing module, an accumulation/incubation module, and a detection module. The detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from the chemistry of the biological sample to determine the amount of an analyte in the biological sample.

Abstract: High throughput screening is performed by directing an array tape (60) provided with a plurality of wells arranged in rows and columns into a dispensing well plate device (25) having various row and column actuators (40, 50). With the wells containing samples to be tested, activating select ones of row and column actuators (40, 50) of the dispensing well plate device (25), as well causing relative shifting between the actuators (40, 50) and the array tape (60), enables fluid to be dispensed from one or more nozzles of the dispensing well plate device (25) into predetermined ones of the plurality of wells in a wide range of patterns.

Abstract: A carrier tape (20) wound on and extending between first and second spools (40) rotatably mounted to a read head (12) is submerged with a detector (44) mounted on a guide mechanism (42) into a fluid thermal media in the form of water or air contained in tanks (76-79). While submerged, the carrier tape (20) can be wound from one spool (40) to another. Further, the read head (12) can be plunged multiple times in opposite directions in the fluid thermal media. The detector (44) allows readings while the carrier tape (20) and the contents carried thereby are submerged in the fluid thermal media and can be a multi-channel, time-resolving photometer measuring fluorescence with at least one channel per row of wells (30) arranged in an array.

Abstract: A plurality of reagent dispensing tips (15) are inserted through frustoconical openings (28) in a cover (16) of a cleaning chamber in the form of intersecting axial bores (14) and sprayed with wash fluid from spray passages (34) in the peripheral wall (20) of the cover (16). Wash fluid from the spray passages (34) and flowing through the reagent dispensing tips (15), if hollow, can be drained from the cleaning chamber through a drain port (42). Air is drawn through the frustoconical openings (28) around the reagent dispensing tips (15) into the cleaning chamber, through filter element (64) and from a waste chamber (50) by a vacuum source (78) to remove wash fluid from and otherwise dry the reagent dispensing tips (15).

Abstract: A heat tunnel for applying heated air to articles enclosed in shrink-wrap film includes at least one air supply unit; a conveyor; and a heat shroud spaced from the conveyor. The air supply unit includes a source of heated air, a fan, a heated air plenum, air ducts, and a return air plenum. Multiple air supply units can be provided along the conveyor to create a heat tunnel of desired length.

Abstract: A carrier tape (20) wound on and extending between first and second spools (40) rotatably mounted to a read head (12) is submerged with a detector (44) mounted on a guide mechanism (42) into a fluid thermal media in the form of water or air contained in tanks (76-79). While submerged, the carrier tape (20) can be wound from one spool (40) to another. Further, the read head (12) can be plunged multiple times in opposite directions in the fluid thermal media. The detector (44) allows readings while the carrier tape (20) and the contents carried thereby are submerged in the fluid thermal media and can be a multi-channel, time-resolving photometer measuring fluorescence with at least one channel per row of wells (30) arranged in an array.

Abstract: High throughput screening is performed by directing an array tape (60) provided with a plurality of wells arranged in rows and columns into a dispensing well plate device (25) having various row and column actuators (40, 50). With the wells containing samples to be tested, activating select ones of row and column actuators (40, 50) of the dispensing well plate device (25), as well causing relative shifting between the actuators (40, 50) and the array tape (60), enables fluid to be dispensed from one or more nozzles of the dispensing well plate device (25) into predetermined ones of the plurality of wells in a wide range of patterns.

Abstract: A cutting apparatus cuts shrink wrap film residing in a roll. The apparatus includes a first roller pair receiving the film from the roll and carrying the film away from the roll; and without the need for a second roller pair to receive the cut sheet of film. Film snap-back is prevented by cutting the film between a shear deck with teeth and a rotating blade with teeth intermeshing with the teeth of the shear deck. A method for cutting a sheet of shrink wrap film, includes: feeding the film into a first roller pair; and cutting the film between the first roller pair and the second roller pair using a rotating knife with a number of teeth intermeshing with a shear bar with teeth.

Abstract: Apparatus selectively processes a substrate using radiant energy. The substrate can consist of any target material having a portion to be processed using the radiant energy and a larger portion to be unprocessed. The apparatus includes a source of radiant energy (preferably a quantum cascade laser) that has a customizable spectrum that can be configured to be specifically absorbed only by the portion to be processed, and a control system for targeting the radiant energy only at the portion to be processed. Specific examples of the use of the apparatus and method are in the technologies of heat-shrinking polyethylene film, fusing toner to paper in a laser printer, heating reaction vessels in DNA testing, and temperature profiling bottle pre-forms.

Abstract: A heat tunnel for applying heated air to articles enclosed in shrink-wrap film includes at least one air supply unit; a conveyor; and a heat shroud spaced from the conveyor. The air supply unit includes a source of heated air, a fan, a heated air plenum, air ducts, and a return air plenum. Multiple air supply units can be provided along the conveyor to create a heat tunnel of desired length.

Abstract: Product is conveyed as a continuous stream by a meter conveyor (12) unto a transfer plate (32) and a transfer device (42). The transfer device (42) is movable between a retracted position and an extended position extending over a sweep conveyor (22). In a preferred form, the transfer device (42) is in the form of a thin piece of flexible material and is moved in the conveying direction from the retracted position to the extended position by engaging with the sweep conveyor (22) and is moved to the retracted position by being wrapped around a rotated roller (46). Product is transferred from the transfer device (42) to the sweep conveyor (22) as the transfer device (42) moves from the extended position to the retracted position and is engaged by a metering bar (52ba, 52ca) which controls the product on the sweep conveyor (22) until the product group leaves the transfer device (42). With nested product, the leading edge of the transfer device (42) is scalloped to represent the product bottom leading edge.

Abstract: A method for enclosing articles in heat-shrink film and for perforating or slitting the heat shrink film.

Abstract: A heat tunnel for applying heated air to articles enclosed in shrink-wrap film includes at least one air supply unit; a conveyor; and a heat shroud spaced from the conveyor. The air supply unit includes a source of heated air, a fan, a heated air plenum, air ducts, and a return air plenum. Multiple air supply units can be provided along the conveyor to create a heat tunnel of desired length.

Abstract: Product is conveyed as a continuous stream by a meter conveyor (12) unto a transfer plate (32) and a transfer device (42). The transfer device (42) is movable between a retracted position and an extended position extending over a sweep conveyor (22). In a preferred form, the transfer device (42) is in the form of a thin piece of flexible material and is moved in the conveying direction from the retracted position to the extended position by engaging with the sweep conveyor (22) and is moved to the retracted position by being wrapped around a rotated roller (46). Product is transferred from the transfer device (42) to the sweep conveyor (22) as the transfer device (42) moves from the extended position to the retracted position and is engaged by a metering bar (52ba) which controls the product acceleration on the sweep conveyor (22) to match the meter conveyor (12) until the product group leaves the transfer device (42).

Abstract: A heat tunnel for applying heated air to articles enclosed in shrink-wrap film includes at least one air supply unit; a conveyor; and a heat shroud spaced from the conveyor. Tha air supply unit includes a source of heated air, a fan, a heated air plenum, air ducts, and a return air plenum. Multiple air supply units can be provided along the conveyor to create a heat tunnel of desired length.

Abstract: Product is conveyed as a continuous stream by a meter conveyor (12) unto a transfer plate (32) and a transfer device (42). The transfer device (42) is movable between a retracted position and an extended position extending over a sweep conveyor (22). In a preferred form, the transfer device (42) is in the form of a thin piece of flexible material and is moved in the conveying direction from the retracted position to the extended position by engaging with the sweep conveyor (22) and is moved to the retracted position by being wrapped around a rotated roller (46). Product is transferred from the transfer device (42) to the sweep conveyor (22) as the transfer device (42) moves from the extended position to the retracted position and is engaged by a metering bar (52ba) which controls the product acceleration on the sweep conveyor (22) to match the meter conveyor (12) until the product group leaves the transfer device (42).

Abstract: Product is conveyed as a continuous stream by a meter conveyor (12) unto a transfer plate (32) and a transfer device (42). The transfer device (42) is movable between a retracted position and an extended position extending over a sweep conveyor (22). In a preferred form, the transfer device (42) is in the form of a thin piece of flexible material and is moved in the conveying direction from the retracted position to the extended position by engaging with the sweep conveyor (22) and is moved to the retracted position by being wrapped around a rotated roller (46). Product is transferred from the transfer device (42) to the sweep conveyor (22) as the transfer device (42) moves from the extended position to the retracted position and is engaged by a metering bar (52ba) which controls the product acceleration on the sweep conveyor (22) to match the meter conveyor (12) until the product group leaves the transfer device (42).

Abstract: An apparatus for perforating or slitting heat shrink film. The apparatus consists of a rotating perforating wheel having a number of sharpened teeth, with dull portions between the teeth. The apparatus may also include a slitter for slitting the film.

Abstract: A heat tunnel for applying heated air to articles enclosed in shrink-wrap film. The heat tunnel includes at least one air supply unit, the air supply unit further having a source of heated air, a fan, a heated air plenum, air ducts, and a return air plenum; a conveyor chain; and a heat shroud spaced from the conveyor chain. Multiple air supply units can be provided along the conveyor to create a heat tunnel of desired length.

Abstract: Product is conveyed as a continuous stream by a meter conveyor (12) unto a transfer plate (32) and a transfer device (42). The transfer device (42) is movable between a retracted position and an extended position extending over a sweep conveyor (22). In a preferred form, the transfer device (42) is in the form of a thin piece of flexible material and is moved in the conveying direction from the retracted position to the extended position by engaging with the sweep conveyor (22) and is moved to the retracted position by being wrapped around a rotated roller (46). Product is transferred from the transfer device (42) to the sweep conveyor (22) as the transfer device (42) moves from the extended position to the retracted position and is engaged by a metering bar (52ba) which controls the product acceleration on the sweep conveyor (22) to match the meter conveyor (12) until the product group leaves the transfer device (42).