Abstract: In one aspect, the invention relates to a composition including a first polypeptide having the sequence set forth in SEQ ID NO: 1 and a second polypeptide having the sequence set forth in SEQ ID NO: 2. In one embodiment, the composition includes about 120 ?g/ml of a first polypeptide including the amino acid sequence set forth in SEQ ID NO: 1, 120 ?g/ml of a second polypeptide including the amino acid sequence set forth in SEQ ID NO: 2, about 2.8 molar ratio polysorbate-80 to the first polypeptide, about 2.8 molar ratio polysorbate-80 to the second polypeptide, about 0.5 mg/ml aluminum, about 10 mM histidine, and about 150 mM sodium chloride. In one embodiment, a dose of the composition is about 0.5 ml in total volume. In one embodiment, two-doses of the composition induce a bactericidal titer against diverse heterologous subfamily A and subfamily B strains in a human.

Abstract: A system that includes a failed test detector and a task updater can automatically update tasks associated with consistent failures of software tests in a software development management platform. The failed test detector can use a set of evidence of test (EOT) files that indicate software testing results over a period of time to identify tests that are consistently failing when executed against versions of a software application. The task updater can automatically create tasks associated with such consistently-failing tests in the software development management platform. The task updater can also automatically close existing tasks associated with tests, in the software development management system, if the failed test detector determines that those tests are no longer failing consistently.

Abstract: The present invention is directed to compounds of formula I The compounds are considered useful for the treatment of diseases associated with LRRK2 such as Parkinson's disease.

Abstract: Geographical mapping and linking of security and risk indicator data. Cross-references are created between location indicators and geo-spatial areas based on a statistical algorithm, in accordance with geo-spatial data. The cross-references are stored in a first data table. A credit risk indicator (CRI) is generated for each geo-spatial area based on other data, forming CRI data that is stored in second data table. A security associated with one of the location indicators is identified among security data. A first link is created between the security and a geo-spatial area based on the cross-references in the first data table. Based on the first link, a second link is created between an indicator among the CRI data in the second data table and the security. The second link is used to form instrument-level data for the security that includes the indicator. The instrument-level data is stored in a third data table.

Abstract: A method of polymerizing a first, and a second class of monomers to form product polymer. The first class of monomers polymerize via a radical pathway in the presence of light, and the second class of monomers polymerize via an insertion pathway in the absence of light.

Abstract: The present invention relates to polypeptides and cytomegalovirus (CMV) antigens that include at least one introduced amino acid mutation relative to the amino acid sequence of the wild-type HCMV glycoprotein B (gB). In some embodiments, the polypeptide is stabilized in a conformation alternative to the gB postfusion conformation. Also disclosed are compositions including the polypeptides and uses thereof.

Abstract: Impingement insert for an airfoil of a blade/vane of a gas turbine is provided. The impingement insert includes a double-walled section having an outer and an inner walls, that define—an inner channel at an inner surface of the inner wall, an outer channel at an outer surface of the outer wall and a middle channel between the outer and the inner walls. Impingement cooling holes are provided in the outer wall that use the cooling air of the middle channel to eject impingement jets into the outer channel. The impingement insert includes at least one extraction duct that extends between the outer and the inner walls across the middle channel, and has an inlet at the outer channel, and an outlet at the inner channel, for flowing the cooling air, after impingement, from the outer channel into the inner channel.

Abstract: A method, system, and computer program product for predicting microservices required for incoming requests for reducing the start latency of serverless microservices. The method may include obtaining tracing data of microservices of an application for historical requests processed by the application. The method may also include grouping the tracing data based on common request attributes. The method may also include aggregating each group into rules relating the common request attributes to lists of microservices. The method may also include building a predictive model formed of the rules for processing incoming requests to obtain a list of predicted microservices required for the incoming request based on attributes of the incoming request.

Abstract: An impingement insert for an airfoil of a turbomachine component is provided. The insert includes first and second body parts, each having inner and outer surfaces; and first and second contact parts provided on the outer surfaces of the first and the second body parts. The insert includes a flexible mechanical seal part between the body parts. A flow channel for cooling air is defined by the seal part and the inner surfaces of the body parts. One or both of the body parts include impingement holes. The insert has an elastic part connected to the body parts. When the elastic part is subjected to deformation, the elastic part is configured to apply a force, on the first and/or the second body parts, in a direction of increasing a separation between the first contact part and the second contact part.

Abstract: A turbine vane is provided.

Abstract: The present disclosure provides for unique onion plants with disease resistance and desirable bulb color and their progeny. Such plants may comprise an introgressed QTL associated with multiple disease resistance coupled with a desirable bulb color. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, breeding, identifying, selecting, and the like of plants or germplasm with disease resistance and/or desirable bulb color are provided.

Abstract: A timeline generation and solving tool is provided to parameterize a project at an application lifecycle management (“ALM”) tool, and generate and solve a timeline of features according to the parameterized project. The Scrum master may re-parameterize the project, causing a new timeline to be generated, solved, and visualized. In this fashion, the Scrum master may rapidly prototype many project parameterizations, resulting in many possible timelines. Without the use of a timeline generation and solving tool which interfaces with an ALM tool, retrieves project features, and converts project features to a common format suitable for computations based on working speeds, a Scrum master would need to generate and check a timeline by hand, and work indirectly by manually copying data out of the ALM tool, leading to a slow and potentially error-prone project roadmapping process which does not permit rapid prototyping of possible timelines.

Abstract: Systems and methods for enabling auditing access to protected data stored at a data service using smart contracts on a blockchain are disclosed. According to certain aspects, a compliance management system may maintain and update a public blockchain with transaction indicative of non-compliance events associated with access to the protected data. Auditors or other third parties may access the public blockchain to audit the access to the protected data. Additionally, the compliance management system may implement a private blockchain to manage access restrictions to the protected data and process data requests for the protected data.

Abstract: Embodiments herein relate to an apparatus for use in a hybrid laser. The apparatus may include a silicon substrate and a waveguide to facilitate transmission of an optical signal in a first direction that is orthogonal to a surface of the silicon substrate. The apparatus may further include a metal shunt that is less than or equal to 10 micrometers from the waveguide in a second direction that is orthogonal to the surface of the silicon substrate and orthogonal to the first direction. Other embodiments may be described and/or claimed.

Abstract: The present invention presents a ring assembly 1 disposed radially outwardly of an array of circumferentially arranged blades 38 of a gas turbine engine rotor R. The ring assembly 1 includes ring segments 2 disposed circumferentially one adjacent to another and having a first circumferential end 2a and a second circumferential end 2b circumferentially spaced apart from each other. The first end 2a of a ring segment 2 and the second end 2b of an adjacent ring segment 2 of the plurality of ring segments 2 are arranged facing each other. An integrally formed projecting seal part 92 is formed at the first end 2a. An integrally formed receiving seal part 94 is formed at the second end 2b facing the first end 2a. The receiving seal part 94 receives the projecting seal part 92 to form a mating connection between the ring segment 2 and the adjacent ring segment 2. A gas turbine engine including the ring assembly 1 is also provided.

Abstract: A simulated payload apparatus (SPA) for testing in a flight motion system (FMS), which has a body for mounting in the FMS, and which simulates an actual payload during the FMS test. The SPA may include a plurality of adjustable weights that are mountable on and/or removable from the body to vary the mass and/or center of gravity of the SPA. The SPA may include an adjustable bracket for interfacing with a motion drive of the FMS, in which the bracket is positionable along the body to vary the moment of inertia of the SPA. The SPA may include an onboard electronic measurement device that is configured to measure a motion characteristic of the SPA and/or communicate information about the measured motion characteristic in real-time during the FMS test. The SPA may include a laser alignment for aligning the SPA relative to test equipment of the FMS.

Abstract: NEW MATERIAL: Recombinant plasmid pTPGIF2 having a size of 4,660 base pairs and a structure obtained by inserting a DNA having a size of 52 base pairs and containing a sequence coding somatostatin into a BamHI incision site of a plasmid vector pTP70-1 capable or fusing a heteropeptide to a carboxy-terminal of a dihydrofolic acid reductase gene of E. coli. USE: Producton of fused protein containing somatostatin. PREPARATION: A somatostatin gene is integrated into a plasmid vector pTP70-1. pTPGIF2 is kept in stable state when introduced into E. coli. C600 strain. The E. coli. C600 train containing pTPGIF2 is deposited in Fermentation Research institute as FERM BP-1577.

Abstract: The present technique presents a turbomachine component having an airfoil e.g. a vane of a gas turbine. The airfoil wall defines an internal space which includes a first and a second cooling channels having a first and a second impingement inserts, that define a first main and a first peripheral flow channels in the first cooling channel and a second main and a second peripheral flow channels in the second cooling channel, respectively. Impingement jets ejected from the main flow channels via impingement holes of the corresponding impingement inserts are received in the corresponding peripheral flow channels. A channel connecting conduit conducts a flow of the cooling air from the first cooling channel to the second cooling channel. The channel connecting conduit includes an inlet connected to an outlet of the first cooling channel, and an outlet connected to an inlet of the second cooling channel.

Abstract: A photonic integrated circuit including having a semiconductor substrate having integrated a semiconductor light source, the semiconductor light source comprising: an optically active section comprising a gain section and configured to support a first number of wavelengths, an optically passive section comprising a passive waveguide optically coupled to the optically active section and a passive section mirror optically coupled to the passive waveguide, wherein the optically passive section is configured to support a second number of wavelengths that is lower than the first number; and the optically passive section further comprising a signal shifting structure configured to shift a signal of the light supported by the passive waveguide.

Abstract: The present disclosure provides for unique onion plants with QTLs conferring Fusarium basal rot and pink root resistance and lacking the complementary pinks trait and their progeny. Such plants may comprise an introgressed QTL associated with multiple disease resistance coupled with a desirable bulb color. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, breeding, identifying, selecting, and the like of plants or germplasm with disease resistance and/or desirable bulb color are provided.