Patents by Inventor Richard K. Cooper

Richard K. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200379526
    Abstract: An electronic device can include a frame configured to receive and support an electronic component, a shell defining an internal volume sized to encompass the frame and the electronic component, the shell being slidably removable from the frame, the electronic component positioned within the internal volume and including an aperture, and a sealing member including a seal body and a compressible lip extending from the seal body, the sealing member at least partially surrounding the electronic component. The compressible lip is oriented such that the shell compresses the lip in a direction against the seal body at a first position adjacent to the electronic component and in the direction against the seal body at a second position adjacent to the electronic component opposite the first position.
    Type: Application
    Filed: September 27, 2019
    Publication date: December 3, 2020
    Inventors: Bart K. Andre, Edward J. Cooper, Brett W. Degner, Houtan R. Farahani, Steven A. Gerasimoff, William H. Greenbaum, James T. Handy, Daniel D. Hershey, PengYuan Huang, Eric A. Knopf, Richard D. Kosoglow, Mariel L. Lanas, Michael E. Leclerc, Michael D. McBroom, Rodrigo Dutervil Mubarak, David C. Parell, Sabrina K. Paseman, Eric R. Prather, Jacob W. Rutheiser, Christopher G. Siegel, Cheng-Han Yang, James M. Cuseo, Francesco Ferretti
  • Patent number: 9157097
    Abstract: The present invention provides novel compositions to transfect cells for production of growth hormone (GH). These novel compositions also are used to produce germline transgenic birds that can successfully pass the transgene encoding growth hormone to their offspring. These novel compositions include components of vectors such as a vector backbone, a novel promoter, and a gene of interest that encodes for GH, and the vectors comprising these components. In one embodiment these vectors are transposon-based vectors. The present invention also provides methods of making these compositions and methods of using these compositions for the production of GH in vitro and in vivo. In one embodiment the GH is human (h)GH.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: October 13, 2015
    Assignee: PROTEOVEC HOLDING, L.L.C.
    Inventors: Richard K. Cooper, William C. Fioretti
  • Patent number: 9150880
    Abstract: Novel compositions for the production of the light and heavy chains of an antibody are provided. These novel compositions are also used to produce germline transgenic birds that can successfully pass the transgene encoding the antibody to their offspring. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes the light or heavy chain of an antibody, and the vectors comprising these components. In certain embodiments, these vectors are transposon-based vectors. Also provided are methods of making these compositions and methods of using these compositions for the production of the light and heavy chains of an antibody. In one embodiment, the antibody is a human monoclonal antibody.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: October 6, 2015
    Assignee: PROTEOVEC HOLDING, L.L.C.
    Inventors: Richard K. Cooper, William C. Fioretti
  • Patent number: 9150881
    Abstract: Novel compositions for the in vitro or in vivo production of specific proteins are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes for the protein of interest, and the transposon-based vectors comprising these components. Also provided are methods of making these compositions and methods of using these compositions for the production of desired proteins in vivo or in transfected cells in vitro.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: October 6, 2015
    Assignee: PROTEOVEC HOLDING, L.L.C.
    Inventors: Richard K. Cooper, William C. Fioretti
  • Patent number: 8283518
    Abstract: Methods and compositions for the administration of transposon-based vectors to the reproductive organs of animals and the creation of transgenic animals. Preferred methods involve administration of the transposon-based vectors to the lumen of the oviduct of an avian, expression of a vector derived transgene in the avian, and deposition of the resultant polypeptide in an egg. This invention allows for large amounts of protein to be deposited in the egg.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 9, 2012
    Assignees: TransGenRx, Inc., The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, William C. Fioretti, Gary G. Cadd
  • Patent number: 8236294
    Abstract: Methods and compositions are presented for the administration of transposon-based vectors to an animal or human to provide gene therapy to the animal or human.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: August 7, 2012
    Assignees: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, TransGenRx, Inc.
    Inventors: Richard K. Cooper, Frederick M. Enright, William C. Fioretti
  • Publication number: 20100261227
    Abstract: Novel compositions for the in vitro or in vivo production of specific proteins are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes for the protein of interest, and the transposon-based vectors comprising these components. Also provided are methods of making these compositions and methods of using these compositions for the production of desired proteins in vivo or in transfected cells in vitro.
    Type: Application
    Filed: April 9, 2010
    Publication date: October 14, 2010
    Applicants: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, TransGenRx, Inc.
    Inventors: Richard K. Cooper, William C. Fioretti
  • Publication number: 20100099148
    Abstract: Novel compositions for the production of the light and heavy chains of an antibody are provided. These novel compositions are also used to produce germline transgenic birds that can successfully pass the transgene encoding the antibody to their offspring. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes the light or heavy chain of an antibody, and the vectors comprising these components. In certain embodiments, these vectors are transposon-based vectors. Also provided are methods of making these compositions and methods of using these compositions for the production of the light and heavy chains of an antibody. In one embodiment, the antibody is a human monoclonal antibody.
    Type: Application
    Filed: September 25, 2009
    Publication date: April 22, 2010
    Inventors: Richard K. Cooper, William C. Fioretti
  • Publication number: 20100093036
    Abstract: The present invention provides novel compositions to transfect cells for production of growth hormone (GH). These novel compositions also are used to produce germline transgenic birds that can successfully pass the transgene encoding growth hormone to their offspring. These novel compositions include components of vectors such as a vector backbone, a novel promoter, and a gene of interest that encodes for GH, and the vectors comprising these components. In one embodiment these vectors are transposon-based vectors. The present invention also provides methods of making these compositions and methods of using these compositions for the production of GH in vitro and in vivo. In one embodiment the GH is human (h)GH.
    Type: Application
    Filed: September 25, 2009
    Publication date: April 15, 2010
    Inventors: RICHARD K. COOPER, WILLIAM C. FIORETTI
  • Publication number: 20100081789
    Abstract: Novel compositions for the production of interferons such as interferon-? 2a, interferon-? 2b, or interferon-? 1a (IFN-? 2a, IFN-? 2b, or IFN-? 1a) are provided. The compositions comprise components of vectors, such as a vector backbone, a promoter, and a gene of interest that encodes an interferon such as IFN-? 2a, IFN-? 2b, or IFN-? 1a, and the vectors comprising these components. In certain embodiments, these vectors are transposon-based vectors. Also provided are methods of making these compositions and methods of using these compositions for the production of an interferon such as IFN-? 2a, IFN-? 2b, or IFN-?1a.
    Type: Application
    Filed: September 25, 2009
    Publication date: April 1, 2010
    Inventors: RICHARD K. COOPER, WILLIAM C. FIORETTI
  • Patent number: 7608451
    Abstract: Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 27, 2009
    Assignees: Transgen Rx, Inc., The Board of Supervisors of Louisiana State University and Mechanical College
    Inventors: Richard K. Cooper, Gary G. Cadd, William C. Fioretti, Kenneth F. De Boer
  • Patent number: 7527966
    Abstract: Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: May 5, 2009
    Assignees: TransGenRx, Inc., The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, Gary G. Cadd, William C. Fioretti, Kenneth F. De Boer
  • Publication number: 20090047235
    Abstract: A paratransgenesis system is disclosed to kill targeted social insects such as termites and cockroaches, for example the Formosan subterranean termite. A genetically modified yeast can be effectively used to express and deliver lytic peptides directly within the termite gut. Some highly lytic peptides directly damage the insect gut itself, leading to the death of the insect within about three days. Other lytic peptides kill all (or at least most) species of protozoa in the termite gut. The protozoa provide wood-digesting enzymes (cellulases) to the termite. Without these protozoa (and their cellulases) the insect dies within about six weeks. The system is completely free from conventional neurotoxins and other organic pesticides.
    Type: Application
    Filed: May 15, 2008
    Publication date: February 19, 2009
    Inventors: Claudia R. Husseneder, James A. Ottea, Lane D. Foil, Frederick M. Enright, Richard K. Cooper
  • Publication number: 20080235813
    Abstract: Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 25, 2008
    Inventors: Richard K. Cooper, Gary G. Cadd, William C. Fioretti, Kenneth F. De Boer
  • Publication number: 20080235815
    Abstract: Methods and compositions for the administration of transposon-based vectors to the reproductive organs of animals and the creation of transgenic animals. Preferred methods involve administration of the transposon-based vectors to the lumen of the oviduct of an avian, expression of a vector derived transgene in the avian, and deposition of the resultant polypeptide in an egg. This invention allows for large amounts of protein to be deposited in the egg.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 25, 2008
    Inventors: Richard K. Cooper, William C. Fioretti, Gary G. Cadd
  • Publication number: 20040235011
    Abstract: The present invention provides a new, effective and efficient method of producing multimeric proteins in an individual. Multimeric proteins include associated multimeric proteins (two or more associated polypeptides) and multivalent multimeric proteins (a single polypeptide encoded by more than one gene of interest). Expression and/or formation of the multimeric protein in the individual is achieved by administering a polynucleotide cassette containing genes of interest that encode portions of the multimeric protein to the individual. The polynucleotide cassette may additionally contain one or more pro sequences, prepro sequences, cecropin prepro sequences, and/or cleavage site sequences.
    Type: Application
    Filed: December 24, 2003
    Publication date: November 25, 2004
    Inventors: Richard K. Cooper, William C. Fioretti, Gary G. Cadd
  • Publication number: 20040197910
    Abstract: Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.
    Type: Application
    Filed: June 26, 2003
    Publication date: October 7, 2004
    Inventors: Richard K. Cooper, Gary G. Cadd, William C. Fioretti, Kenneth F. De Boer
  • Publication number: 20040172667
    Abstract: Methods and compositions for the administration of transposon-based vectors to the reproductive organs of animals and the creation of transgenic animals. Preferred methods involve administration of the transposon-based vectors to the lumen of the oviduct of an avian, expression of a vector derived transgene in the avian, and deposition of the resultant polypeptide in an egg. This invention allows for large amounts of protein to be deposited in the egg.
    Type: Application
    Filed: December 24, 2003
    Publication date: September 2, 2004
    Inventors: Richard K. Cooper, William C. Fioretti, Gary G. Cadd
  • Patent number: 6156568
    Abstract: Novel means have been discovered for increasing the resistance of an animal host (including humans) to diseases caused by intracellular bacteria, protozoa, and viruses. The infection treated may, for example, be equine infectious anemia, or infection by the human immunodeficiency virus. Novel means have also been found for treating tumors. Augmentation of the host's defenses against infectious diseases or tumors is achieved by "arming" the host's cells with an exogenous gene encoding a natural or synthetic lytic peptide. For example, the transfection of hematopoietic stem cells and embryonic cells will produce animals with enhanced disease resistance; and transfection of TIL (tumor infiltrating lymphocytes) cells or other cells can be used in the treatment of tumors. Genes coding for a cecropin or other native or synthetic lytic peptide can be transferred and stably expressed in mammalian, bony fish, other vertebrate, and other animal cells.
    Type: Grant
    Filed: July 16, 1997
    Date of Patent: December 5, 2000
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Richard K. Cooper, Frederick M. Enright
  • Patent number: 6010705
    Abstract: Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion mutations in the aroA gene, the purA gene, or both. These vaccines may be used not only to vaccinate fish against Edwardsiella ictaluri or Pasteurella piscicida, but also to serve as vectors to present antigens from other pathogens to the fish, thereby serving as vaccines against other pathogens as well, with no risk of infection by reversion to the virulent form of the pathogen in which the antigen occurs naturally.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: January 4, 2000
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Ronald L. Thune, Richard K. Cooper