Patents by Inventor Richard L. Wolgemuth

Richard L. Wolgemuth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4831019
    Abstract: Antineoplastic pharmaceutical preparations and a method for treating neoplastic conditions using 4-demethoxy-N-trifluoroacetyldaunomycin and 4-demethoxy-N-trifluoroacetyldoxorubicin.
    Type: Grant
    Filed: May 22, 1985
    Date of Patent: May 16, 1989
    Assignee: Adria Laboratories, Inc.
    Inventors: Richard L. Wolgemuth, John P. Carter
  • Patent number: 4772688
    Abstract: Compounds of the formula (I) and pharmaceutical preparations containing the same are disclosed ##STR1## wherein R.sup.1 is --OOCR.sup.3 or --OOC(CH.sub.2).sub.n COOR.sup.4 ; R.sup.2 is hydrogen, hydroxy or methoxy; one of X and X' is a halogen atom selected from the group consisting of fluorine, chlorine, bromine and iodine and the other is hydrogen; one of Y and Y' is hydrogen and the other is selected from the group consisting of hydrogen, hydroxy and acyloxy; one of Z and Z' is hydrogen and the other is selected from the group consisting of hydrogen, hydroxy and acyloxy; R.sup.3 is an alkyl group containing 1 to 8 carbon atoms; R.sup.4 is a hydrogen atom, a metal atom, or an alkyl group containing 1 to 4 carbon atoms; and n is an integer of 0 to 6. These compounds are active in the inhibition of malignant diseases.
    Type: Grant
    Filed: April 23, 1987
    Date of Patent: September 20, 1988
    Assignee: Ohio State University Research Foundation
    Inventors: Derek Horton, Waldemar Priebe, Richard L. Wolgemuth
  • Patent number: 4590063
    Abstract: Compounds of the formula ##STR1## where R is a methyl, ethyl or propyl group and n is 1 or 2 and their nontoxic salts are useful as anticonvulsants.
    Type: Grant
    Filed: April 25, 1985
    Date of Patent: May 20, 1986
    Assignee: Adria Laboratories, Inc.
    Inventors: John P. Carter, Jr., Richard L. Wolgemuth
  • Patent number: 4540814
    Abstract: Compounds of the formula ##STR1## where R is a methyl, ethyl or propyl group and n is 1 or 2 and their nontoxic salts are useful as anticonvulsants.
    Type: Grant
    Filed: June 24, 1983
    Date of Patent: September 10, 1985
    Assignee: Adria Laboratories, Inc.
    Inventors: John P. Carter, Jr., Richard L. Wolgemuth
  • Patent number: 4395392
    Abstract: A method for decreasing urinary calcium content which comprises orally administering to a person whose urine contains insoluble calcium containing precipitates or has a propensity for forming calcium containing precipitates, an effective amount of an agent selected from water-soluble vinylbenzenesulfonic acid polymers and the nontoxic pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: June 29, 1981
    Date of Patent: July 26, 1983
    Assignee: Adria Laboratories Inc.
    Inventor: Richard L. Wolgemuth
  • Patent number: 4223109
    Abstract: The calcium salts of the solid cyclic copolymers of divinyl ether and maleic anhydride, soluble in water, have been found to be as effective in treating tumors and viruses as the prior art alkali metal salts (e.g., the sodium salt) but much less toxic. These copolymers are characterized by containing divinyl ether and maleic anhydride in a mole ratio of about 1:2, having a molecular weight of from about 2000 to about 100,000 and from about 5% to about 70% of its carboxylic acid groups converted to calcium salts.
    Type: Grant
    Filed: February 22, 1979
    Date of Patent: September 16, 1980
    Assignee: Adria Laboratories Inc.
    Inventor: Richard L. Wolgemuth
  • Patent number: 4171352
    Abstract: A quantitative evaluation of the intestinal microflora is made by administering to an animal organism an effective amount of novel chemical conjugates of a bile acid or related acid with an amino acid which will be cleaved from the bile or related acid by the enzymes elaborated by the intestinal microflora and then measuring the amount of the released amino acid in the urine after a predetermined time interval. The novel compounds and their use in in vitro tests are included in the invention.
    Type: Grant
    Filed: August 22, 1977
    Date of Patent: October 16, 1979
    Assignee: Polysciences, Inc.
    Inventors: Richard L. Wolgemuth, Kenneth M. Hanson, Peter H. Zassenhaus
  • Patent number: 4143130
    Abstract: Water soluble and colloidially water soluble polymers of carboxylic acid-containing monomers useful for treating kidney stones are disclosed.
    Type: Grant
    Filed: August 29, 1977
    Date of Patent: March 6, 1979
    Assignee: Warren-Teed Laboratories, Inc.
    Inventors: Anthony R. Imondi, Richard L. Wolgemuth