Abstract: A method of reducing the abundance of a non-target micro-RNA (miRNA) that is part of a group of miRNAs is provided, including: (a) annealing a complementary region of a blocking nucleic acid to a binding site at a first end of the unwanted miRNA, ligating an adenylated nucleic acid adapter to the group of miRNAs, and performing RT-PCR on group of miRNAs. Kits and compounds for use with the method are also provided.

Abstract: The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: An active clamp switching power converter circuit includes a primary-side sensing circuit that generates a sensed voltage based on an auxiliary winding voltage of an auxiliary winding around the core having a same polarity as the primary winding. Based on the sensed voltage, a controller controls switching of a power switch coupled to the primary winding to control current through the primary winding and controls switching of an active clamp switch to control leakage current when the power switch is turned off. The controller regulates timing of the switching to turn on the power switch based on timing of a zero voltage switching condition for power efficient operation.

Abstract: An active clamp switching power converter circuit includes a sensing circuit that generates a sensed auxiliary winding voltage of an auxiliary winding around the core having a same polarity as the secondary winding. A controller controls switching of a power switch coupled to the primary winding to control current through the primary winding and controls switching of an active clamp switch based on the sensed voltage to control leakage energy when the power switch is turned off. The controller regulates timing of the switching to achieve a zero voltage switching condition prior to turning on the power switch for power efficient operation.

Abstract: An active clamp switching power converter circuit includes a sensing circuit that generates a sensed auxiliary winding voltage of an auxiliary winding around the core. A primary side controller controls switching of a power switch coupled to a primary winding to control current through the primary winding and controls switching of the active clamp switch based on the sensed voltage to control leakage energy when the power switch is turned off. The primary side controller regulates timing of the switching to achieve a zero voltage switching condition prior to turning on the power switch for power efficient operation.

Abstract: An active clamp switching power converter circuit includes a sensing circuit that generates a sensed auxiliary winding voltage of an auxiliary winding around the core having a same polarity as the secondary winding. A controller controls switching of a power switch coupled to the primary winding to control current through the primary winding and controls switching of an active clamp switch based on the sensed voltage to control leakage energy when the power switch is turned off. The controller regulates timing of the switching to achieve a zero voltage switching condition prior to turning on the power switch for power efficient operation.

Abstract: The present disclosure provides for and relates to cancer treatment based on the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: An active clamp switching power converter circuit includes a primary-side sensing circuit that generates a sensed voltage based on an auxiliary winding voltage of an auxiliary winding around the core having a same polarity as the primary winding. Based on the sensed voltage, a controller controls switching of a power switch coupled to the primary winding to control current through the primary winding and controls switching of an active clamp switch to control leakage current when the power switch is turned off. The controller regulates timing of the switching to turn on the power switch based on timing of a zero voltage switching condition for power efficient operation.

Abstract: An active clamp switching power converter circuit includes a sensing circuit that generates a sensed auxiliary winding voltage of an auxiliary winding around the core. A primary side controller controls switching of a power switch coupled to a primary winding to control current through the primary winding and controls switching of the active clamp switch based on the sensed voltage to control leakage energy when the power switch is turned off. The primary side controller regulates timing of the switching to achieve a zero voltage switching condition prior to turning on the power switch for power efficient operation.

Abstract: An active clamp switching power converter circuit includes a primary-side sensing circuit that generates a sensed voltage based on an auxiliary winding voltage of an auxiliary winding around the core having a same polarity as the primary winding. Based on the sensed voltage, a controller controls switching of a power switch coupled to the primary winding to control current through the primary winding and controls switching of an active clamp switch to control leakage current when the power switch is turned off. The controller regulates timing of the switching to turn on the power switch based on timing of a zero voltage switching condition for power efficient operation.

Abstract: The present disclosure provides for and relates to cancer treatment based on the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: A method of reducing the abundance of a non-target micro-RNA (miRNA) that is part of a group of miRNAs is provided, including: (a) annealing a complementary region of a blocking nucleic acid to a binding site at a first end of the unwanted miRNA, ligating an adenylated nucleic acid adapter to the group of miRNAs, and performing RT-PCR on group of miRNAs. Kits and compounds for use with the method are also provided.

Abstract: The present disclosure provides for and relates to novel fusion proteins and polypeptides expressed by breast cancer and other cancer cells, and to compositions, materials and methods for detecting, characterizing and treating said breast and other cancers. In one embodiment, the fusion polypeptides are read-through fusion transcripts.

Abstract: The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: A blocking nucleic acid for use in reducing the abundance of a non-target micro-RNA (miRNA) in an miRNA library is provided, including: a single-stranded complementary region at one of the 5? end of the blocking nucleic acid or the 3? end of the blocking nucleic acid, that anneals with a binding region at a first end of the unwanted miRNA; a hairpin loop forming region or other double-stranded region adjacent to the complimentary region, in which all of the terminal ends of the blocking nucleic acid except one are unavailable to participate in ligase reactions. Methods and kits for using the blocking nucleic acid are also provided.

Abstract: A blocking nucleic acid for use in reducing the abundance of a non-target micro-RNA (miRNA) in an miRNA library is provided, including: a single-stranded complementary region at one of the 5? end of the blocking nucleic acid or the 3? end of the blocking nucleic acid, that anneals with a binding region at a first end of the unwanted miRNA; a hairpin loop forming region or other double-stranded region adjacent to the complimentary region, in which all of the terminal ends of the blocking nucleic acid except one are unavailable to participate in ligase reactions. Methods and kits for using the blocking nucleic acid are also provided.

Abstract: The present disclosure provides for and relates to novel fusion proteins and polypeptides expressed by breast cancer and other cancer cells, and to compositions, materials and methods for detecting, characterizing and treating said breast and other cancers. In one embodiment, the fusion polypeptides are read-through fusion transcripts.

Abstract: The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth.

Abstract: A system and methods are provided for controlling a motor of a rod pumping system using previous RPMs of the motor and predicting an RPM of the motor; correcting a power factor of a motor of a rod pumping system; allocating energy consumption and allocating energy generation for a set of wells connected to an electricity meter using an amount of energy generated by each well; and generating an alert if a set of data is beyond a threshold for the set of data.