Abstract: A multiple projectile cartridge for a handgun comprises four spherical projectiles embedded within a paraffin/powder filler material contained within a plastic casing enclosed in a conventional small caliber shell containing the usual primer assembly and powder charge. The projectiles each have a diameter slightly less than the internal casing diameter which maximizes the number of shots and mass traveling at high velocity to strike the target. The single row of projectiles are longitudinally spaced from each other by the filler material so that the projectiles do not crunch together during flight, resulting in a shot string held together in a close pattern of high ballistic integrity. The diametral relationship (i.e., clearance) between the projectile diameter and internal casing diameter also prevents the plastic casing side wall from laterally expanding as the casing travels through the gun barrel to prevent groove fouling.