Abstract: Exemplary arthroplasty systems and methods involve the implantation of a first implant having a convex bearing surface portion and a subchondral surface portion, and a second implant having a concave bearing surface portion and a subchondral surface portion, where the implants are configured for implantation into a joint of a patient to treat an osteochondral defect therein. The joint may be a knee joint, a shoulder joint, a hip joint, an ankle joint, a first metatarsal-phalangeal joint, or the like. In exemplary embodiments, the joint is a knee joint, the first implant is a femoral implant, and the second implant is a tibial implant.

Abstract: A suture fixation device and method thereof is provided. The suture fixation device includes a suture fiber having a length of about 24 to 40 inches and a plurality of knots spaced apart from each other along the length of the suture fiber. Each of the plurality of knots has an overall width of about 3.0 to 4.0 mm.

Abstract: A suture fixation device and method thereof is provided. The suture fixation device includes a suture fiber having a length of about 24 to 40 inches and a plurality of knots spaced apart from each other along the length of the suture fiber. Each of the plurality of knots has an overall width of about 3.0 to 4.0 mm.

Abstract: A device and method for applying compressive hot or cold therapy to a patient's body, including a handle and a frame connected to and extending from the handle. The frame includes two spaced apart support arms, the support arms each having an opening such that the openings in the support arms are collinear with one another. A roller having a central axis and a reservoir within its interior for retaining a thermal medium, the roller having a non-uniform cross-section along its length defining a thermally conductive external surface for transferring thermal energy from the thermal medium to the patient's body. At least one elongated member is operatively connected to the roller and extends longitudinally along the central axis beyond the periphery of the roller. The elongated member is received within the collinear openings of the spaced apart support arms to releasably and rotatably connect the roller to the frame.

Abstract: A thermal therapy device including a hollow roller having a non-uniform cross-section along its length and a thermally conductive external surface. Two end caps, one on each end of the hollow roller, which, in combination with the thermally conductive external surface of the hollow roller, collectively define a thermal-medium-receiving reservoir and a central axis about which the hollow roller may rotate. A pair of pins, one on each of the end caps, are longitudinally aligned along the central axis.

Abstract: Disclosed herein are methods for reducing or preventing scar tissue formation by administering an antifibrotic amount of a fluoroquinolone. Also disclosed are means for inhibiting the activity of fibroblast cells, including their proliferation, metabolism, and invasion into tissue. The invention further contemplates methods and compositions for the delivery of a fluoroquinolone to prevent or treat scar tissue formation, including oral and intravenous delivery means.