Abstract: The invention is directed to methods for massively parallel template-free enzymatic synthesis of a plurality of different polynucleotides of predetermined sequences. In one aspect, methods of the invention employ large scale arrays of reaction sites each associated with at least one working electrode for controlling deprotection and deblocking steps at predetermined user selected sites. In another aspect, the invention provides template-free enzymatic synthesis with proofreading, wherein completed polynucleotides at predetermined reaction sites are sequenced using a sequencing by synthesis technique, particularly employing electrochemically labile blocking groups.

Abstract: A system and method for target driven peer-zoning (TDPZ) synchronization can include a principal member device and a switch. The principal member device can include to send an active peer zone list request to a switch. In an example, the principal member device can store a first TDPZ database version number and a first TDPZ zone list. In an example, the switch may send a response based on the active peer zone list request. In an example, the response can include a second TDPZ database version number and a second TDPZ zone list. The principal member device may compare the first TDPZ database version number to the second TDPZ database version number.

Abstract: A reel weight measurement system is shown and described herein. In some embodiments, the reel weight measurement system comprises strategically placed position and load sensors for measuring an orientation of a reel-carrying unit and measuring loads in the reel-carrying unit. The loads may be indicative of forces due to the weight of the reel when the reel is supported by a carriage of the reel-carrying unit. The weight of the reel may be determined by summing the forces and moments in the system while the carriage is in motion or static. Further, the weight of the reel may be determined by comparing the force measurements and orientation of the carriage to stored calibration data.

Abstract: There is described a multi-unit dose dry powder medicament delivery device comprising: a first element comprising a single use nozzle located in a body which is at least partially lined with an inner member, said inner sleeve comprising an airway and a cartridge seat; and a second element adapted to be releasably attached to the first element, said second element comprising an actuator provided with an air source and a valve.

Abstract: A system and method for target driven peer-zoning (TDPZ) synchronization can include a principal member device and a switch. The principal member device can include to send an active peer zone list request to a switch. In an example, the principal member device can store a first TDPZ database version number and a first TDPZ zone list. In an example, the switch may send a response based on the active peer zone list request. In an example, the response can include a second TDPZ database version number and a second TDPZ zone list. The principal member device may compare the first TDPZ database version number to the second TDPZ database version number.

Abstract: A specialized low drop-out voltage regulator (LDO) computer system stores a generalized base model of an LDO. The base model includes values representing a circuit topology and a set of analog behavior blocks associated with the generalized LDO. Values of a set of operational parameters associated with a specific model of LDO are input to the specialized LDO computer system from a data sheet associated with the specific model of LDO. The specialized LDO computer system transforms the set of operational parameters into a computer model of the specific LDO. The LDO-specific computer model is output as a netlist or as a set of instantiation control values to control external hardware such as an integrated circuit die tooling system or a computer graphical display system.

Abstract: A coated glazing comprising at least the following layers in sequence: a transparent glass substrate, a layer based on an oxide of a metal and/or a layer based on an oxide of a metalloid, and a further layer, wherein either said layer based on an oxide of a metal or said layer based on an oxide of a metalloid is adjacent said transparent glass substrate, wherein said layer that is adjacent said transparent glass substrate comprises a surface that, prior to a coating of said surface, has an arithmetical mean height of the surface value, Sa, of at least 4.0 nm when tested in accordance with ISO 25178-2:2012, and wherein the coated glazing exhibits an average haze value of at least 0.47% when tested in accordance with ASTM D1003-13.

Abstract: This device was brought about for the need to help in illuminating work areas where details could be overlooked when a bright lighting is unavailable. The ease of use, the multiple applications, light weight, brightness and longevity of the battery life make this a very unique and useful tool enhancer.

Abstract: Peptide analogues of ?-amyloid and methods of using said analogues for neuroprotection are described herein. The ?-amyloid peptide analogues have a sequence that is at least 50% identical to an N-terminal ?-amyloid core fragment. A pharmaceutical composition of the ?-amyloid peptide analogues in a pharmaceutically acceptable carrier can be administered to a subject for neuromodulation. The ?-amyloid peptide analogues, while lacking neurotoxicity, effectively provides for protective activity against ?-amyloid toxicity.

Abstract: The present invention relates to a method of depositing a coating comprising zinc oxide on a substrate; to a chemical vapour deposition precursor mixture for use in same and to a coated glass article and a photovoltaic cell prepared with a zinc oxide coating prepared using the method which comprises: providing a substrate, providing a precursor mixture comprising an alkyl zinc compound and a phosphorus source, the phosphorus source comprising a compound of formula OnP(OR)3, wherein n is 0 or 1 and each R is hydrocarbyl, and delivering the precursor mixture to a surface of the substrate.

Abstract: A filter apparatus includes a first housing having a wall defining a first cavity, a first end and a second end; a removable lid configured to be coupled to the first end of the first housing; a cap removably coupled to the removable lid such that a second cavity is defined between a portion of the cap and a portion of the removable lid; and a second housing having a wall defining a third cavity, a first end and a second end, where the second housing is disposed inside the first cavity, and where the first end is configured to be removably coupled to the removable lid independently from the first housing.

Abstract: A specialized low drop-out voltage regulator (LDO) computer system stores a generalized base model of an LDO. The base model includes values representing a circuit topology and a set of analog behavior blocks associated with the generalized LDO. Values of a set of operational parameters associated with a specific model of LDO are input to the specialized LDO computer system from a data sheet associated with the specific model of LDO. The specialized LDO computer system transforms the set of operational parameters into a computer model of the specific LDO. The LDO-specific computer model is output as a netlist or as a set of instantiation control values to control external hardware such as an integrated circuit die tooling system or a computer graphical display system.

Abstract: A specialized low drop-out voltage regulator (LDO) computer system stores a generalized base model of an LDO. The base model includes values representing a circuit topology and a set of analog behavior blocks associated with the generalized LDO. Values of a set of operational parameters associated with a specific model of LDO are input to the specialized LDO computer system from a data sheet associated with the specific model of LDO. The specialized LDO computer system transforms the set of operational parameters into a computer model of the specific LDO. The LDO-specific computer model is output as a netlist or as a set of instantiation control values to control external hardware such as an integrated circuit die tooling system or a computer graphical display system.

Abstract: There is described a dry powder medicament delivery device comprising: a medicament container containing a unit dose of dry powder medicament; a medicament dispensing assembly; and optionally an air source.

Abstract: Transparent conducting electrodes incorporate an interface layer located on the transparent conducting oxide (TCO) layer of the electrode. The interface layer offers a suitable surface for deposition of further layers in order to fabricate electronic devices such as electrochromic devices or organic light emitting diodes. Problems such as pinholes and short circuiting, associated with the inherent roughness of the TCO layer, are reduced.

Abstract: A method of coating a substrate with zinc oxysulphate (ZnO(1-x)Sx, where 0?x?1) by atmospheric pressure chemical vapour deposition is disclosed. Various precursors offering sources of zinc, oxygen and sulphur are provided.

Abstract: Solar collector apparatus is described in which solar radiation is collected in a glazed cavity which may also include a transpired solar collector layer. Air warmed in the cavity may be used for space heating within buildings or diverted to heat management systems which facilitate, for example, heat storage. The glazing, particularly coated glazings, improve the performance of the devices by allowing solar energy to enter the cavity and preventing heat loss, and by negating the effect of ambient wind on the transpired solar collector layer.

Abstract: A system comprising a visual element for indicating the security of a pipe fitting and associated method. The visual element is configured to adhere to an outer surface of a pipe fitting and disjoin from the outer surface of the pipe fitting according to a set of disjoining criteria. The criteria comprises at least one of application of a sufficient force at the outer surface of the pipe fitting to form a fluid-tight seal between the pipe fitting and another pipe and a circumferential change of the visual element greater than a threshold amount of circumferential change. The visual element may be placed on a pipe fitting into which a pipe is inserted, and the connection between the pipe fitting and the pipe may be secured. Determination of whether the pipe fitting and the pipe are properly connected is performed based on monitoring of the visual element.

Abstract: Transparent conducting electrodes incorporate an interface layer located on the transparent conducting oxide (TCO) layer of the electrode. The interface layer offers a suitable surface for deposition of further layers in order to fabricate electronic devices such as electrochromic devices or organic light emitting diodes. Problems such as pinholes and short circuiting, associated with the inherent roughness of the TCO layer, are reduced.

Abstract: A transparent conducting electrode is disclosed having a coating stack structure, including a dielectric layer, a functional layer based on silver, a barrier layer and a further dielectric layer. The unique coating stack offers an electrode having requisite electrical properties and the ability to withstand elevated temperatures associated with further treatment, e.g. in the manufacture of photovoltaic devices.