Patents by Inventor Robert B. Zurier

Robert B. Zurier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING FIBROTIC DISEASES USING TETRAHYDROCANNABINOL-11-OIC ACIDS
    Publication number: 20180116999
    Abstract: This invention is in the field of medicinal chemistry and relates to novel compounds, and pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring/wound healing abnormalities, post operative adhesions, and reactive fibrosis. The invention also relates to methods of using the compounds and pharmaceutical compositions of this invention to treat fibrotic conditions.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 3, 2018
    Inventors: Robert B. ZURIER, Enrico SELVI
  • METHODS OF TREATING FIBROTIC DISEASES USING TETRAHYDROCANNABINOL-11-OIC ACIDS
    Publication number: 20160367518
    Abstract: This invention is in the field of medicinal chemistry and relates to novel compounds, and pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring/wound healing abnormalities, post operative adhesions, and reactive fibrosis. The invention also relates to methods of using the compounds and pharmaceutical compositions of this invention to treat fibrotic conditions.
    Type: Application
    Filed: February 29, 2016
    Publication date: December 22, 2016
    Inventors: Robert B. Zurier, Enrico Selvi
  • METHODS OF TREATING FIBROTIC DISEASES USING TETRAHYDROCANNABINOL-11-OIC ACIDS
    Publication number: 20120309820
    Abstract: This invention is in the field of medicinal chemistry and relates to novel compounds, and pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring/wound healing abnormalities, post operative adhesions, and reactive fibrosis. The invention also relates to methods of using the compounds and pharmaceutical compositions of this invention to treat fibrotic conditions.
    Type: Application
    Filed: May 31, 2012
    Publication date: December 6, 2012
    Inventors: Robert B. Zurier, Enrico Selvi
  • LIPID-AMINO ACID CONJUGATES AND METHODS OF USE
    Publication number: 20100069491
    Abstract: N-fatty acid-amino acid conjugates and J2 prostanoid-amino acid conjugates are disclosed along with methods for making such conjugates and methods of using these conjugates in the treatment of conditions that involve dysfunctional lipid metabolism, insulin sensitivity, glucose homeostasis, and/or inflammation.
    Type: Application
    Filed: June 5, 2009
    Publication date: March 18, 2010
    Applicant: University of Massachusetts
    Inventors: Sumner H. Burstein, Robert B. Zurier
  • Lipid-amino acid conjugates and methods of use
    Patent number: 7544714
    Abstract: N-fatty acid-amino acid conjugates and J2 prostanoid-amino acid conjugates are disclosed along with methods for making such conjugates and methods of using these conjugates in the treatment of conditions that involve dysfunctional lipid metabolism, insulin sensitivity, glucose homeostasis, and/or inflammation.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: June 9, 2009
    Assignee: University of Massachusetts
    Inventors: Sumner H. Burstein, Robert B. Zurier
  • Methods for decreasing cell proliferation based on (3r,4r)-?8-tetrahydrocannabinol-11-oic acids
    Patent number: 6974835
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: December 13, 2005
    Assignee: Indevus Pharmaceuticals, Inc.
    Inventors: Sumner Burstein, Lawrence Recht, Robert B. Zurier
  • Cannabinoid drugs
    Patent number: 6914072
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: July 5, 2005
    Assignee: Indevus Pharmaceuticals, Inc.
    Inventors: Sumner Burstein, Lawrence Recht, Robert B. Zurier
  • Cannabinoid drugs
    Publication number: 20040225011
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Application
    Filed: September 17, 2003
    Publication date: November 11, 2004
    Inventors: Summer Burstein, Lawrence Recht, Robert B. Zurier
  • N-fatty acid-amino acid conjugates and therapeutic uses
    Publication number: 20040197399
    Abstract: The present invention relates to the use of N-fatty acid-amino acid conjugates to treat, prevent, or manage tissue inflammation, leukocyte adhesion, or pain. The invention includes pharmaceutical compositions comprising N-fatty acid-amino acid conjugates and methods of administering N-fatty acid-amino acid conjugates and pharmaceutical compositions thereof as therapeutic agents.
    Type: Application
    Filed: December 23, 2003
    Publication date: October 7, 2004
    Applicant: University of Massachusetts, a Massachusetts corporation
    Inventors: Sumner H. Burstein, Robert B. Zurier
  • Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
    Publication number: 20040186166
    Abstract: The present invention provides for methods and compositions for using cannabinoid compounds, such as ajulemic acid, for the treatment of disorders involving peroxisome proliferator-activated receptor-gamma (PPAR&ggr;). In particular, the invention provides for methods and compositions for treating disorders, such as autoimmune or inflammatory disorders, involving PPAR&ggr;, such as rheumatoid arthritis and diabetes.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 23, 2004
    Inventors: Sumner H. Burstein, J. Don Chen, Robert B. Zurier
  • Methods for decreasing cell proliferation based on (3r,4r)-delta8-tetrahydrocannabinol-11-oic acids
    Publication number: 20040054007
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Application
    Filed: September 17, 2003
    Publication date: March 18, 2004
    Inventors: Summer H Burstein, Lawrence Recht, Robert B. Zurier
  • N-fatty acid-amino acid conjugates and therapeutic uses
    Publication number: 20030022938
    Abstract: The present invention relates to the use of N-fatty acid-amino acid conjugates to treat, prevent, or manage tissue inflammation, leukocyte adhesion, or pain. The invention includes pharmaceutical compositions comprising N-fatty acid-amino acid conjugates and methods of administering N-fatty acid-amino acid conjugates and pharmaceutical compositions thereof as therapeutic agents.
    Type: Application
    Filed: June 25, 2002
    Publication date: January 30, 2003
    Inventors: Sumner H. Burstein, Robert B. Zurier
  • Cannabinoid drugs
    Patent number: 6448288
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Grant
    Filed: May 8, 2001
    Date of Patent: September 10, 2002
    Assignee: University of Massachusetts
    Inventors: Sumner H. Burstein, Lawrence D. Recht, Robert B. Zurier
  • Cannabinoid drugs
    Publication number: 20020022653
    Abstract: The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.
    Type: Application
    Filed: May 8, 2001
    Publication date: February 21, 2002
    Inventors: Sumner H. Burstein, Lawrence D. Recht, Robert B. Zurier