Patents by Inventor Robert Bruce Register

Robert Bruce Register has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical compositions containing rofecoxib and methods of making and using the same
    Patent number: 11931452
    Abstract: The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation.
    Type: Grant
    Filed: January 21, 2022
    Date of Patent: March 19, 2024
    Assignee: JF Pharma Tech LLC
    Inventor: Robert Bruce Register
  • TOPICAL COMPOSITIONS CONTAINING ROFECOXIB AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220265546
    Abstract: The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation.
    Type: Application
    Filed: January 21, 2022
    Publication date: August 25, 2022
    Inventor: Robert Bruce REGISTER
  • Topical compositions containing rofecoxib and methods of making and using the same
    Patent number: 11260023
    Abstract: The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: March 1, 2022
    Assignee: BRIORI BIOTECH, LLC
    Inventor: Robert Bruce Register
  • TOPICAL COMPOSITIONS CONTAINING ROFECOXIB AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20210220259
    Abstract: The present disclosure provides topical compositions of rofecoxib and methods of making said compositions. The present disclosure also provides methods of using topical compositions of rofecoxib to treat inflammation.
    Type: Application
    Filed: February 23, 2021
    Publication date: July 22, 2021
    Inventor: Robert Bruce REGISTER
  • Assays using amyloid precursor proteins with modified beta-secretase cleavage sites to monitor beta-secretase activity
    Publication number: 20030200555
    Abstract: Provided are methods of identifying inhibitors of &bgr;-secretase that employ modified &bgr;-secretase substrates. The modified &bgr;-secretase substrates have &bgr;-secretase cleavage sites that are altered from wild type. The amino acid sequences of the altered &bgr;-secretase cleavage sites contain different amino acids in at least one of the positions P2-P1-P1′-P2′ of the &bgr;-secretase cleavage site. Many of the modified &bgr;-secretase substrates are more efficient substrates for &bgr;-secretase than are corresponding substrates having wild-type sequences, that is, these modified substrates are more susceptible to enzymatic breakdown by &bgr;-secretase. Recombinant polynucleotide molecules encoding the modified &bgr;-secretase substrates are provided. Antibodies that recognize cleavage products of the modified &bgr;-secretase substrates are provided. Stable cell lines expressing the modified &bgr;-secretase substrates are provided.
    Type: Application
    Filed: April 30, 2003
    Publication date: October 23, 2003
    Inventors: Daria Jean Hazuda, Elizabeth Chen Dodson, Ming-Tain Lai, Min Xu, Xiao-Ping Shi, Adam J. Simon, Guoxin Wu, Yueming Li, Robert Bruce Register