Abstract: A composite article, which may be beneficially applied to the skin, includes a thermoplastic gelatinous elastomer composition, which is formed into a composite by heat with a substrate material. The gelatinous elastomer includes at least one hydrogenated styrene/isoprene/butadiene block copolymers and at least one polymer or copolymer of the group poly(styrene-butadiene-styrene), poly(styrene-butadiene), poly(styrene-isoprene-styrene), poly(styrene-isoprene), poly(styrene-ethylene-propylene), poly(styrene-ethylene-propylene-styrene), poly(styrene-ethylene-butylene-styrene) or poly(styrene-ethylene-butylene). The thermoplastic gelatinous elastomer composition further includes a non-oil plasticizer, which may be a specialty ester, an animal-derived non-oil material for imparting an esthetic property and emolliency to a cosmetic formulation, or a combination thereof. The specialty esters preferably include long-chain fatty acids estified with long-chain alcohols and gycols.

Abstract: A composition and method are described for suppressing or preventing fibrous adhesion formation using a multicomponent aqueous oxychlorine composition. Fibrous adhesions typically form during healing of tissue, for example following a surgical procedure. A multicomponent oxychlorine composition is provided for irrigating the tissue which minimizes post-surgical adhesion formation, the composition containing both chlorine dioxide and chlorite ion, and a complex ion thereof. The chlorine dioxide level generally is in an effective range of ClO2 concentration from about 10 ppm to a maximum of about 110 ppm. In a preferred embodiment, a physiological composition is provided in a thickened form to increase retention in the area being treated.

Abstract: This invention relates generally to compositions and methods useful for oral hygiene rinses, and more specifically to oral rinses in which the antimicrobial activity of chlorous acid is supplemented by that of lactic acid as one of a combination of antimicrobial acids, preferably acids which serve to partially convert chlorite ion to chlorous acid.

Abstract: The present invention provides a composition, substantially a lotion, containing a source of nitrite ions and water. The composition, substantially a lotion, is preferably provided in two distinct and separate formulations. One of these formulations may or may not contain a source of nitrite ions. The composition is easily washed off with soap and water and is useful in preventing or treating bacterial, viral, parasitic or fungal infections. Further, the invention provides methods for preventing or treating bacterial, viral, parasitic or fungal infections by applying a pharmaceutically effective amount of the composition topically to the skin. Still further, the invention provides a kit comprising the composition of according to the invention together with instructions for applying the composition topically.

Abstract: A method for transiently and controllably enhancing the adhesion of a hydrogel composition to select substrates for facilitating the handling of the hydrogel composition during processing, includes the steps of placing the hydrogel composition in a liquid state onto a plastic film facestock, which has biaxially-oriented polypropylene, microporous cellulose acetate or a combination thereof, for temporarily adhering the hydrogel composition to the sheets of the roll stock during processing of the hydrogel composition, and then removing the hydrogel composition from the sheets of the roll stock, after processing of the hydrogel composition is complete, without any adverse affect on the textural qualities of the hydrogel composition.

Abstract: A composition for dry cow udder protection includes a bimodal interpenetrating polymer system having both cationic and anionic functionalities and capable of forming a stable aqueous solution and ionic bonds between polar chains. The bimodal inter-penetrating polymer system, preferably, includes two acrylate copolymers, Polyacrylate-18 and Polyacrylate-19. The bimodal interpenetrating polymer system is approximately 20% to approximately 40%, by weight, of the aqueous solution, and preferably has a thixotropic viscosity of from approximately 500 cps to approximately 5,000 cps, as measured with a Brookfield Viscometer at 20 rpm with a #3 spindle. The composition, as part of an aqueous solution, is applied to the region of a cow teat to be protected and allowed to dry, resulting in a water-insoluble protecting film.

Abstract: The invention relates to long-acting nitrous acid compositions that disinfect inanimate surfaces and animal tissues, and that can be used to treat diseases and wounds. Compositions of the invention are single-phase, metastable nitrous acid solutions that exhibit enhanced germicidal efficacy and can have an effective lifetime exceeding several years. Compositions of the invention have a wide variety of applications that include, but are not limited to, teat dips, oral rinses, instrument sterilization, and disinfection of food.

Abstract: The invention provides methods comprising applying an aqueous solution comprising a reducing agent to meat disinfected with an oxidizing germicide, wherein application of the aqueous solution to the meat reduces meat discoloration caused by the oxidizing germicide.

Abstract: This invention relates generally to compositions and methods useful for oral hygiene rinses, and more specifically to oral rinses in which the antimicrobial activity of chlorous acid is supplemented by that of lactic acid as one of a combination of antimicrobial acids, preferably acids which serve to partially convert chlorite ion to chlorous acid.

Abstract: The invention provides aqueous disinfecting (germicidal) dip compositions comprising opacifying complexes formed by the reaction of cationic organic quaternary ammonium compounds (“quats”)and anionic organic sulfonates. The compositions are particularly useful as dairy cow teat dips. Complexes formed by the reaction of quats and organic sulfonates provide turbidity and opacity to these aqueous germicidal dip compositions. Such turbidity and opacity serve to enhance the visibility of the compositions, e.g., when applied to an animal's teat.

Abstract: A method for strengthening a hydrogel of a naturally-occurring gelling agent, or a derivative thereof, including the step of adding at least one glycol to the gelling agent of the general formula: HO—(CH2)n—OH, HO—(CH2—CH2O)x—H, HO—(CH2—CH2—CH2O)y—H; and, HO—(CH2—CH[CH3]—O)y—H, in which, n is from 2 to about 8; x is from 6 to about 30; and, y is from 4 to about 20. Also useful of those of the general structure: HO—[C(R1)(R2)—C(R3)(R4)]—OH, in which, R1, R2, R3, R4 are capable of being —H in all four positions, or H in 0, 1, 2, 3 positions and —CH3 or —C2H5 in any or all of the non-H occupied positions.

Abstract: The present invention relates generally to compositions and methods for the use of nitrous acid solutions to disinfect inanimate surfaces and animal tissues, and to treat diseases and wounds. More specifically, the invention deals with the partial and selected conversion of nitrite ion to nitrous acid in order to optimize the germicidal efficacy and duration of the nitrous acid consistent with the nature of the intended application.

Abstract: The present invention is directed to disinfecting compositions for dental unit water lines, particularly effective against microbial flora in biofilms which form on the luminal walls of the piping and reservoir components of dental equipment, as well as methods related to the use of such compositions to reduce microbial numbers in water-bearing dental and other equipment and maintain reduced levels on a continuous basis.

Abstract: The present invention is directed to disinfecting compositions for dental unit water lines, particularly effective against microbial flora in biofilms which form on the luminal walls of the piping and reservoir components of dental equipment, as well as methods related to the use of such compositions to reduce microbial numbers in water-bearing dental and other equipment and maintain reduced levels on a continuous basis.

Abstract: There is provided a surfactant composition that is capable of attacking lipids of the nits. The surfactant is an anionic surfactant.

Abstract: A frozen chlorine dioxide-containing composition comprising a metal chlorite and a protic acid in a frozen aqueous matrix made by freezing a substantially chloride dioxide-free aqueous solution comprising a metal chlorite at a concentration ranging from about 0.0005% to about 0.5% by weight and a protic acid at a concentration sufficient to lower the pH of the aqueous solution to a value of about 1.8 to about 5.0. The frozen chlorine dioxide-containing composition has a chlorine dioxide concentration of more than about 3 ppm, while the aqueous solution prior to freezing has a chlorine dioxide concentration less than about 3 ppm. The frozen chlorine dioxide-containing composition is used to disinfect substrates by contacting the same with the frozen chlorine dioxide-containing composition. Suitable substrates include food intended for human or animal consumption, such as meat, fish and poultry.

Abstract: The present invention is directed to both physical and chemical means for maintaining continuous high levels of chlorine dioxide in aqueous solutions for extended periods, with minimum loss through degradation in the solution and dissipation through the walls of the containing vessel within which the solution is stored. The ClO2 may be maintained even in the absence of very high levels of chlorite, from which supplemental, offsetting levels of ClO2 may be generated. The present invention relates to the discovery that certain types of plastic and glass containers have the ability to maintain relatively constant levels of ClO2 in their contained solutions over extended periods, particularly in aqueous compositions comprising chlorite/ClO2 ratios sufficient for a stabilizing complex of the two, presumably Cl204—, to suppress the ClO2 loss.

Abstract: An animal feed composition for reducing colonization of animal intestines by Salmonella and other bacterial pathogens, includes a polysaccharide containing cis-hydroxy sugar units or a derivative thereof, or the monosaccharide ribose or rhamnose, or a derivative thereof, and an animal feed. The polysaccharide cis-hydroxy sugar units may be one or more of mannose, a mannose derivative, galactose, a galactose derivative, galactomannans, galactosamine, fucose and arabinose. The polysaccharides may be incorporated into an animal feed in the form of a food gum or other biolpolymer.

Abstract: A stabilized two-part disinfecting system comprising a first part and a second part adapted to be mixed to yield an aqueous disinfecting composition. The first part contains a non-esterifying acid and an alcohol-containing humectant or antifreeze, while the second part contains a salt of an organic acid and an optional metal chlorite. Methods for making a disinfecting composition by mixing the two-part disinfecting system, as well as for disinfecting substrates by contact therewith, are also disclosed.

Abstract: There is disclosed a method for treating dermatologic diseases caused by microbial overgrowth or inflammation, such as psoriasis, fungal infections, eczema, dandruff, acne, genital herpes lesions, and leg ulcers. There is further disclosed an antiviral lubricating composition that is effective in preventing the transmission of the HIV virus and other sexually transmitted diseases. There is also disclosed systemic and anti-inflammatory compositions and formulations and a method for reducing tissue inflammation in tissues such as the bowel, muscle, bone, tendon and joints (e.g., arthritis).