Patents by Inventor Robert Hudkins

Robert Hudkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridizinone derivatives
    Publication number: 20080027041
    Abstract: The present invention provides compounds of formula (I*): their use as H3 inhibitors, processes for their preparation, and pharmaceutical compositions thereof.
    Type: Application
    Filed: July 25, 2007
    Publication date: January 31, 2008
    Applicant: Cephalon, Inc.
    Inventors: Robert Hudkins, Kurt Josef, Ming Tao
  • Fused [d]pyridazin-7-ones
    Publication number: 20070299061
    Abstract: The present invention is directed to fused [d]pyridazin-7-ones. The invention is also directed to methods for making and using the fused [d]pyridazin-7-ones. In particular, the compounds of the present invention may be effective in the treatment of diseases or disease states related to the activity of VEGFR2, MLK1 and CDK5 enzymes, including, for example, angiogenic disorders and neurodegenerative diseases.
    Type: Application
    Filed: June 21, 2007
    Publication date: December 27, 2007
    Applicant: Cephalon, Inc.
    Inventors: Nadine Becknell, Robert Hudkins
  • Substituted pyrazolopyrimidines
    Publication number: 20070281949
    Abstract: The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted heterobicyclic pyrimidines of Formula (I): wherein R1, R2, R3, R4, R5, X, W, and ring A are as defined herein; pharmaceutical compositions of substituted heterobicyclic pyrimidines of Formula (I); and their use in the treatment of chronic neurodegenerative diseases, neurotraumatic diseases, depression and/or diabetes. More particularly, the present invention relates to substituted pyrazolopyrimidines of Formula (I).
    Type: Application
    Filed: May 14, 2007
    Publication date: December 6, 2007
    Applicant: Cephalon, Inc.
    Inventors: Edward Bacon, Thomas Bailey, Nadine Becknell, Diane Gingrich, Greg Hostetler, Robert Hudkins, Keith Learn, Jason Wagner
  • Novel Fused Pyrrolocarbazoles
    Publication number: 20070203135
    Abstract: The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.
    Type: Application
    Filed: May 3, 2007
    Publication date: August 30, 2007
    Applicant: Cephalon, Inc.
    Inventors: Robert Hudkins, Dandu Reddy, Ming Tao, Theodore Underiner, Allison Zulli
  • Novel multicyclic compounds and the use thereof
    Publication number: 20060276497
    Abstract: The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer.
    Type: Application
    Filed: June 19, 2006
    Publication date: December 7, 2006
    Applicant: Cephalon, Inc.
    Inventors: Sankar Chatterjee, James Diebold, Derek Dunn, Robert Hudkins, Reddeppareddy Dandu, Gregory Wells, Allison Zulli
  • Novel fused pyrrolocarbazoles
    Publication number: 20060247294
    Abstract: The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.
    Type: Application
    Filed: June 29, 2006
    Publication date: November 2, 2006
    Applicant: Cephalon, Inc.
    Inventors: Nadine Becknell, James Diebold, Diane Gingrich, Robert Hudkins, Dandu Reddy, Ming Tao, Theodore Underiner, Allison Zulli
  • Selected fused pyrrolocarbazoles
    Publication number: 20060135590
    Abstract: The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.
    Type: Application
    Filed: February 8, 2006
    Publication date: June 22, 2006
    Applicant: Cephalon, Inc.
    Inventors: Diane Gingrich, Robert Hudkins
  • Cyclic substituted fused pyrrolocarbazoles and isoindolones
    Publication number: 20060128780
    Abstract: The present invention is directed to cyclic substituted fused pyrrolocarbazoles and isoindolones. The invention also is directed to methods for making and using the cyclic substituted fused pyrrolocarbazoles and isoindolones.
    Type: Application
    Filed: February 2, 2006
    Publication date: June 15, 2006
    Applicant: Cephalon, Inc.
    Inventors: Robert Hudkins, Dandu Reddy, Jasbir Singh, Rabindranath Tripathy, Ted Underiner
  • Methods of treating proliferative skin diseases using carbazole derivatives
    Publication number: 20060058250
    Abstract: The present invention relates to a method of treating a proliferative skin disease, comprising administering a therapeutically effective amount of a trk inhibitor.
    Type: Application
    Filed: September 8, 2005
    Publication date: March 16, 2006
    Applicant: Cephalon, Inc.
    Inventors: Samuel Denmeade, Robert Hudkins
  • Novel fused pyrrolocarbazoles
    Publication number: 20050143442
    Abstract: The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.
    Type: Application
    Filed: December 22, 2004
    Publication date: June 30, 2005
    Inventors: Robert Hudkins, Allison Zulli, Dandu Reddy, Diane Gingrich, Ming Tao, Nadine Becknell, James Diebold, Theodore Underiner
  • Novel fused pyrrolocarbazoles
    Publication number: 20050137245
    Abstract: The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles.
    Type: Application
    Filed: December 22, 2004
    Publication date: June 23, 2005
    Inventors: Robert Hudkins, Allison Zulli, Dandu Reddy, Ming Tao, Theodore Underiner
  • Isomeric fused pyrrolocarbazoles and isoindolones
    Publication number: 20050107458
    Abstract: The present invention is directed to novel fused pyrrolocarbazoles and isoindolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directed to intermediates and processes for making these novel compounds.
    Type: Application
    Filed: January 5, 2005
    Publication date: May 19, 2005
    Applicant: Cephalon, Inc.
    Inventor: Robert Hudkins