Patents by Inventor Robert L. Schmitt

Robert L. Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230221782
    Abstract: A mobile phone may include an enclosure defining an internal volume, the enclosure including a front cover formed from a transparent material and defining a front exterior surface, a rear cover formed from a glass material and defining a rear exterior surface, and a housing component defining a side exterior surface. The mobile phone may include a circuit board assembly within the internal volume. The circuit board assembly may include a circuit board, a circuit component coupled to an exterior surface of the circuit board, and a cowling coupled to the circuit board and covering the circuit component, the cowling having a thickness less than about 0.5 mm and including a base structure formed from an aluminum alloy having a thickness less than about 0.4 mm and a thermally conductive structure positioned over the base structure and configured to dissipate heat.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 13, 2023
    Inventors: David A. Hurrell, Gregory N. Stephens, Isabel Yang, John J. Baker, Sherry Lee, Matthew D. Hill, Obinna Onyemepu, Douglas G. Fournier, Benjamin J. Pope, Michael W. Firka, Griffin L. Schmitt, Arun R. Varma, Robert Hrabchak
  • Publication number: 20220175822
    Abstract: Embodiments are directed towards methods of inducing caspase activity. The methods include contacting a cell with a treatment compound represented by the following Formula (I), where the treatment compound is a random copolymer, R1 is selected from hydrogen and a hydroxyl group, R2 is selected from hydrogen and a hydroxyl group, R1 is different than R2, and a sum of x and y is from 4 to 20,000.
    Type: Application
    Filed: February 27, 2020
    Publication date: June 9, 2022
    Applicant: Dow Global Technologies LLC
    Inventors: Caroline Woelfle-Gupta, Andrew Scott, Matthew LeBaron, Daniel Wilson, Susan L. Jordan, Robert L. Schmitt, Raja Settivari
  • Publication number: 20220125830
    Abstract: Embodiments are directed towards methods of inducing caspase activity. The methods include contacting a cell with a treatment compound formed by alkoxylation of an initiator using an oxide.
    Type: Application
    Filed: February 26, 2020
    Publication date: April 28, 2022
    Applicant: Dow Global Technologies LLC
    Inventors: Caroline Woelfle-Gupta, Andrew Scott, Matthew LeBaron, Daniel Wilson, Susan L. Jordan, Robert L. Schmitt, Raja Settivari
  • Publication number: 20220054534
    Abstract: Embodiments are directed towards methods of inducing caspase activity. The methods include contacting a cell with a treatment compound represented by the following Formula (I): where R1 is selected from hydrogen or an alkyl group having from 1 to about 16 carbon atoms; R2 is selected from a hydroxyl group, a tosylate group, an alkoxy group of the formula OR3 where R3 is selected from an alkyl group having from 1 to about 16 carbon atoms, or an ester group of the formula OCOR4, where R4 is an alkyl group having from 1 to about 16 carbon atoms, and n is from 4 to 46,000, with the proviso that when R1 is hydrogen and R2 is a hydroxy group the treatment compound has a number average molecular weight from 10,100 to 2,000,0000 g/mol.
    Type: Application
    Filed: February 26, 2020
    Publication date: February 24, 2022
    Applicant: Dow Global Technologies LLC
    Inventors: Caroline Woelfle-Gupta, Andrew Scott, Matthew LeBaron, Daniel Wilson, Susan L. Jordan, Robert L. Schmitt, Raja Settivari
  • Patent number: 11000594
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: May 11, 2021
    Assignee: Dow Global Technologies LLC
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Publication number: 20190209693
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa»s and optionally one or more adjuvants.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Patent number: 10272156
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: April 30, 2019
    Assignee: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Publication number: 20180362737
    Abstract: A composition comprising a) an esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent hydrocarbon group, wherein I) the degree of neutralization of the groups —C(O)—R—COOH is not more than 0.4 and II) the total degree of ester substitution is from 0.03 to 0.70, and b) a cellulose ether having a viscosity of from 1.2 to 200 mPa s, measured as a 2 weight-% aqueous solution at 20° C., gels at increased temperature and displays reduced syneresis when further increasing the temperature of the gel.
    Type: Application
    Filed: November 15, 2016
    Publication date: December 20, 2018
    Applicant: Dow Global Technologies LLC
    Inventors: Oliver PETERMANN, Robert L. SCHMITT
  • Patent number: 9890221
    Abstract: Esterified cellulose ethers comprising groups of formula —C(O)—CHR?—CHR?—COOA, wherein, R? and R? are hydrogen or (—S)m(—R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR?—CHR? one of R? and R? is hydrogen and the other one is (—S)m(—R1)n-R2, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: February 13, 2018
    Assignees: Dow Global Technologies LLC, University of Minnesota
    Inventors: Ligeng Yin, Marc A. Hillmyer, Steven J. Guillaudeu, Robert L. Schmitt
  • Patent number: 9782356
    Abstract: A polymeric capsule shell of high quality is prepared from an aqueous composition which comprises (A) at least one esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent aliphatic or aromatic hydrocarbon group, wherein at least a part of the groups —C(O)—R—COOH are neutralized with an ammonium salt of carbonic acid, formic acid or acetic acid, and (B) from 0 to 7 weight percent of a non-polymeric plasticizer, based on the weight of the esterified cellulose ether, wherein the weight of said at least one esterified cellulose ether is at least 80 percent of the total polymer weight in the aqueous composition.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: October 10, 2017
    Assignee: Dow Global Technologies LLC
    Inventors: Jin Zhao, Roland Adden, Brian Koblinski, Robert L. Schmitt
  • Publication number: 20170181976
    Abstract: A polymeric capsule shell of high quality is prepared from an aqueous composition which comprises (A) at least one esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent aliphatic or aromatic hydrocarbon group, wherein at least a part of the groups —C(O)—R—COOH are neutralized with an ammonium salt of carbonic acid, formic acid or acetic acid, and (B) from 0 to 7 weight percent of a non-polymeric plasticizer, based on the weight of the esterified cellulose ether, wherein the weight of said at least one esterified cellulose ether is at least 80 percent of the total polymer weight in the aqueous composition.
    Type: Application
    Filed: April 28, 2015
    Publication date: June 29, 2017
    Applicant: Dow Global Technologies LLC
    Inventors: Jin Zhao, Roland Adden, Brian Koblinski, Robert L. Schmitt
  • Publication number: 20170028069
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.
    Type: Application
    Filed: October 13, 2016
    Publication date: February 2, 2017
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Patent number: 9486532
    Abstract: Esterified cellulose ethers which comprise (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, which have a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and which have a viscosity of up to 13 mPao·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C. are useful for preparing solid dispersions comprising drugs.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: November 8, 2016
    Inventors: Meinolf Brackhagen, Steven J. Guillaudeu, Nicholas S. Grasman, Oliver Petermann, Robert L. Schmitt, Matthias Sprehe
  • Publication number: 20160289344
    Abstract: Esterified cellulose ethers comprising groups of formula —C(O)—CHR?—CHR?—COOA, wherein, R? and R? are hydrogen or (—S)m (—R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR?—CHR? one of R? and R? is hydrogen and the other one is (—S)m (—R1)n-R?, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.
    Type: Application
    Filed: May 7, 2014
    Publication date: October 6, 2016
    Inventors: Ligeng Yin, Marc A. Hillmyer, Steven J. Guillaudeu, Robert L. Schmitt
  • Patent number: 9320799
    Abstract: An esterified cellulose ether comprises (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein the cellulose ether has anhydroglucose units joined by 1-4 linkages and has methyl groups, hydroxyalkyl groups, and optionally alkyl groups being different from methyl as substituents such that the esterified cellulose ether has an MS (hydroxyalkyl) of 0.05 to 1.00, and hydroxyl groups of anhydroglucose units are substituted with methyl groups such that [s23/s26?0.2*MS(hydroxyalkyl)] is 0.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: April 26, 2016
    Inventors: Robert L. Schmitt, Robert L. Sammler, Meinolf Brackhagen, Oliver Petermann, Roland Adden, Nicholas S. Grasman, Steven J. Guillaudeu
  • Publication number: 20150374831
    Abstract: Esterified cellulose ethers which comprise (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, which have a viscosity of up to 2.33 mPa·s, measured as a 2.0 wt % solution of the esterified cellulose ether in 0.43 wt % aqueous NaOH at 20° C., and which have a viscosity of up to 13 mPao·s, measured as a 10 wt % solution of the esterified cellulose ether in acetone at 20° C. are useful for preparing solid dispersions comprising drugs.
    Type: Application
    Filed: February 28, 2014
    Publication date: December 31, 2015
    Applicant: DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Meinolf Brackhagen, Steven J. Guillaudeu, Nicholas S. Grasman, Oliver Petermann, Robert L. Schmitt, Matthias Sprehe
  • Publication number: 20150320869
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one hydroxypropyl methylcellulose having 28 to 30 weight percent of methoxyl groups, 7 to 12 weight percent of hydroxypropoxyl groups and a sum of methoxyl groups and hydroxypropoxyl groups of from 38.5 to 42 weight percent is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one hydroxypropyl methylcellulose by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one hydroxypropyl methylcellulose described above and optionally one or more adjuvants.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Meinolf Brackhagen, Robert L. Schmitt, Matthias Knarr
  • Publication number: 20150218197
    Abstract: Two or more esters of a cellulose ether, each having the same ether and ester substituents but different weight average molecular weights are prepared in a process which comprises the steps of esterifying a cellulose ether with (i) an aliphatic monocarboxylic acid anhydride or (ii) a dicarboxylic acid anhydride or (iii) a combination of an aliphatic monocarboxylic acid anhydride and a dicarboxylic acid anhydride in the presence of an aliphatic carboxylic acid as a reaction diluent in two or more separate reactions, wherein in each reaction a different molar ratio [aliphatic carboxylic acid/anhydroglucose units of cellulose ether] is used to produce esters of the cellulose ether of different weight average molecular weights.
    Type: Application
    Filed: August 15, 2013
    Publication date: August 6, 2015
    Inventors: Oliver Petermann, Matthias Sprehe, Robert L. Schmitt, Andrew C. Arthur, Warren K. Miller, David K. Lyon
  • Publication number: 20150209436
    Abstract: A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.
    Type: Application
    Filed: July 12, 2013
    Publication date: July 30, 2015
    Inventors: Meinolf Brackhagen, Nicholas S. Grasman, Mark J. Hall, Steven J. Guillaudeu, Robert L. Schmitt, Matthias Knarr
  • Patent number: 9084417
    Abstract: A composition including an ethylene blocking agent complex formed from the product of an ethylene blocking agent and a host, and at least one water-soluble polymer, wherein the ethylene blocking agent complex and the at least one water-soluble polymer are intermingled is disclosed.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: July 21, 2015
    Assignee: Dow AgroSciences LLC
    Inventors: Gretchen Baier, Mark D. Newsham, Irina V. Graf, Robert L. Schmitt, Lamy J. Chopin, III, Jacquelyn A. deGroot, Jeffrey J. Wooster, Tarlochan Singh Dhadialla