Patents by Inventor Robert Langer

Robert Langer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130338773
    Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
    Type: Application
    Filed: June 13, 2012
    Publication date: December 19, 2013
    Inventors: Edward S. Boyden, Gregory J. Della Rocca, Paul Duesterhoft, Daniel Hawkins, Roderick A. Hyde, Robert Langer, Eric C. Leuthardt, Terence Myckatyn, Parag Jitendra Parikh, Dennis J. Rivet, Joshua S. Shimony, Michael A. Smith, Elizabeth A. Sweeney, Clarence T. Tegreene
  • Publication number: 20130338770
    Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
    Type: Application
    Filed: June 13, 2012
    Publication date: December 19, 2013
    Inventors: Edward S. Boyden, Gregory J. Della Rocca, Paul Duesterhoft, Daniel Hawkins, Roderick A. Hyde, Robert Langer, Eric C. Leuthardt, Terence Myckatyn, Parag Jitendra Parikh, Dennis J. Rivet, Joshua S. Shimony, Michael A. Smith, Elizabeth A. Sweeney, Clarence T. Tegreene
  • Publication number: 20130331792
    Abstract: The present disclosure provides devices and uses thereof. A devices disclosed herein comprises one or more tips, wherein the one or more tips are designed and constructed to initiate penetration by the device; and one or more protrusions in a region adjacent to each tip. In some embodiments, one or more protrusions can be constructed and arranged so that the required penetration force is reduced as compared with that observed for an otherwise identical device lacking the one or more protrusions. Additionally or alternatively, one or more protrusions can be constructed and arranged such that the required pull-out force is increased as compared with that observed for an otherwise identical device lacking the one or more protrusions.
    Type: Application
    Filed: January 18, 2012
    Publication date: December 12, 2013
    Applicants: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jeffrey M. Karp, Woo Kyung Cho, Bryan Laulicht, James A. Ankrum, Rohit N. Karnik, Robert Langer
  • Patent number: 8585684
    Abstract: Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: November 19, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Leroy E. Hood, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Clarence T. Tegreene, Lowell L. Wood, Jr., Victoria Y. H. Wood
  • Patent number: 8577693
    Abstract: Methods and systems are described for obtaining a parameter relating to a stent inventory shortage and for specializing one or more stents in response to obtaining the parameter relating to the stent inventory shortage.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: November 5, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., Clarence T. Tegreene, Lowell L. Wood, Jr.
  • Patent number: 8568388
    Abstract: Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: October 29, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Leroy E. Hood, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Clarence T. Tegreene, Lowell L. Wood, Jr., Victoria Y. H. Wood
  • Patent number: 8550344
    Abstract: Methods and systems are described for obtaining a parameter relating to a stent inventory shortage or to a specific patient and for configuring a stent in response. For example, the response may involve configuring a stent with a flow occlusion portion in response to the obtained parameter relating to the stent inventory shortage, configuring a stent with a flow occlusion portion in response to receiving the parameter relating to the specific patient, or specializing one or more stents in response to obtaining the parameter relating to the stent inventory shortage.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: October 8, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., Clarence T. Tegreene, Lowell L. Wood, Jr.
  • Patent number: 8551749
    Abstract: Devices, methods, and systems are described for controlling pathogenic condition or disease in a subject. Devices are described that include one or more bone cages. The device including one or more bone cages can be configured to include one or more immunogens and one or more adjuvants. The device including one or more bone cages can be configured to, and/or structured to at least partially or completely surround one or more cells or tissues that produce one or more immunogens and/or one or more adjuvants. The device is useful in a method for treating a pathogenic condition or disease in the subject.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: October 8, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Ed Harlow, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 8551750
    Abstract: Devices, methods, and systems are described for controlling pathogenic condition or disease in a subject. Devices are described that include one or more bone cages. The device including one or more bone cages can be configured to include one or more immunogens and one or more adjuvants. The device including one or more bone cages can be configured to, and/or structured to at least partially or completely surround one or more cells or tissues that produce one or more immunogens and/or one or more adjuvants. The device is useful in a method for treating a pathogenic condition or disease in the subject.
    Type: Grant
    Filed: July 28, 2009
    Date of Patent: October 8, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Ed Harlow, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Patent number: 8551155
    Abstract: Methods and systems are described for receiving a parameter relating to a specific patient, and for customizing one or more attributes of a stent ex situ as an at-least-roughly contemporaneous response to receiving the parameter relating to the specific patient or for customizing one or more junctions of a stent ex situ in response to the received parameter relating to the specific patient.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: October 8, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., Clarence T. Tegreene, Lowell L. Wood, Jr.
  • Publication number: 20130234367
    Abstract: Endolumenal prostheses that readily and extensively convert from a delivery configuration to a deployed configuration are disclosed. Endolumenal prostheses may be fabricated from one or more shape memory polymers, a high modulus elastomer, a polymer that is both elastomeric and exhibits shape memory behavior, a hydrogel, or some combination thereof. Polymers used to fabricate the prostheses are selectively synthesized to exhibit desired characteristics such as crystallinity, strain fixity rate, strain recovery rate, elasticity, tensile strength, mechanical strength, cross-linking density, extent physical cross-linking, extent of covalent cross-linking, extent of interpenetrating networks, rate of erosion, heat of fusion, crystallization temperature, and acidity during erosion. The endolumenal prostheses convert to the deployed configuration following delivery to a treatment site, upon exposure to an initiator either present within the body naturally or introduced into the body.
    Type: Application
    Filed: January 4, 2013
    Publication date: September 12, 2013
    Applicant: SyneCor LLC
    Inventors: Michael Scott Williams, Yadong Wang, Robert Langer
  • Patent number: 8529551
    Abstract: Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, an acoustic control signal may be used.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: September 10, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Leroy E. Hood, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Clarence T. Tegreene, Lowell L. Wood, Jr., Victoria Y. H. Wood
  • Patent number: 8521440
    Abstract: Systems, methods, compositions and apparatus relating to genome selection are disclosed.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: August 27, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: W. Daniel Hillis, Roderick A. Hyde, Edward K. Y. Jung, Robert Langer, Nathan P. Myhrvold, Lowell L. Wood, Jr.
  • Patent number: 8492143
    Abstract: Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: July 23, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Ed Harlow, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Lowell L. Wood, Jr.
  • Patent number: 8481068
    Abstract: Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: July 9, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Ed Harlow, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Lowell L. Wood, Jr.
  • Patent number: 8475517
    Abstract: Methods and systems are described for receiving a parameter relating to a specific patient, and for customizing one or more attributes of a stent ex situ as an at-least-roughly contemporaneous response to receiving the parameter relating to the specific patient or for customizing one or more junctions of a stent ex situ in response to the received parameter relating to the specific patient.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: July 2, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Jr., Clarence T. Tegreene, Lowell L. Wood, Jr.
  • Patent number: 8454547
    Abstract: Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: June 4, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Muriel Y. Ishikawa, Edward K. Y. Jung, Robert Langer, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
  • Publication number: 20130112924
    Abstract: Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventors: Philip A. Eckhoff, William H. Gates, III, Peter L. Hagelstein, Roderick A. Hyde, Jordin T. Kare, Robert Langer, Erez Lieberman, Eric C. Leuthardt, Nathan P. Myhrvold, Michael Schnall-Levin, Clarence T. Tegreene, Lowell L. Wood, JR.
  • Publication number: 20130112898
    Abstract: Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventors: Philip A. Eckhoff, William H. Gates, III, Peter L. Hagelstein, Roderick A. Hyde, Jordin T. Kare, Robert Langer, Erez Lieberman, Eric C. Leuthardt, Nathan P. Myhrvold, Michael Schnall-Levin, Clarence T. Tegreene, Lowell L. Wood, JR.
  • Publication number: 20130112897
    Abstract: Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition.
    Type: Application
    Filed: November 3, 2011
    Publication date: May 9, 2013
    Inventors: Philip A. Eckhoff, William H. Gates, III, Peter L. Hagelstein, Roderick A. Hyde, Jordin T. Kare, Robert Langer, Erez Lieberman, Eric C. Leuthardt, Nathan P. Myhrvold, Michael Schnall-Levin, Clarence T. Tegreene, Lowell L. Wood, JR.