Patents by Inventor Robert McDowell

Robert McDowell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20010011087
    Abstract: Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula 1,
    Type: Application
    Filed: February 8, 2001
    Publication date: August 2, 2001
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Karlheinz Scheunemann, Jean-Marie Ruxer, Denis Carniato, Jean-Michel Lefrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 6255962
    Abstract: A method and apparatus for low-power sensing and processing are provided. A method preferably includes collecting a plurality of sensor signals. The plurality of sensors include sensed data representative of at least shock and vibration. The method also includes converting the plurality of sensor signals into digital data, processing the digital data, generating a data communications protocol for communicating the digital data, and simultaneously and remotely detecting the generated communications protocol having the processed data to determined the occurrence of at least one predetermined condition. An apparatus preferably includes a low-power, data acquisition processing circuit responsive to a plurality of sensor signals representative of at least shock and vibration for acquiring and processing the sensed data.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: July 3, 2001
    Assignee: System Excelerator, Inc.
    Inventors: Martin Tanenhaus, Robert McDowell, Tom Nelson
  • Patent number: 6218415
    Abstract: Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors The present invention relates to 5-membered ring heterocycles of the formula I, in which E, F, G, W, Y and Z have the meaning given in the patent claims, to their preparation and to their use as medicaments. The novel compounds are used as vitronectin receptor antagonists and as inhibitors of bone reabsorption.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: April 17, 2001
    Assignees: Hoechst Aktiengesellschaft, Genetech, Inc.
    Inventors: Volkmar Wehner, Jochen Knolle, Hans Ulrich Stilz, Denis Carniato, Jean-Francois Gourvest, Tom Gadek, Robert McDowell
  • Patent number: 6218387
    Abstract: The present invention relates to compounds of the formula I, A—B—D—E—F—G  (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: April 17, 2001
    Assignees: Hoechst Aktiengesellschaft, Genetech, Inc.
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Karlheinz Scheunemann, Jean-Marie Ruxer, Denis Carniato, Jean-Michel Lefrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 6207663
    Abstract: Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula I A—B—D—E—F—G   (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: March 27, 2001
    Assignees: Hoechst Atkiengesellschaft, Genentech, Inc.
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Jochen Knolle, Jean-Marie Ruxer, Denis Carniato, Jean-Michel LeFrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 6011045
    Abstract: The present invention relates to compounds of the formula IA--B--D--E--F--G (I)in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: January 4, 2000
    Assignees: Hoechst Aktiengesellschaft, Genentech, Inc.
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Jochen Knolle, Jean-Marie Ruxer, Denis Carniato, Jean-Michel Lefrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 6005117
    Abstract: There are described imino derivatives of formula (I)R.sup.1 --Y--A--B--D--E--F--G (I)their preparation and their use as medicaments. The compounds according to the invention may be used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: December 21, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Volkmar Wehner, Jochen Knolle, Hans Ulrich Stilz, Jean-Francois Gourvest, Denis Carniato, Thomas Richard Gadek, Robert McDowell, Robert Maurice Pitti, Sarah Catherine Bodary
  • Patent number: 5990145
    Abstract: The present invention relates to compounds of the formula I,A--B--D--E--F--G (I)in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: November 23, 1999
    Assignees: Hoechst Aktiengesellschaft, Genentech, Inc.
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Anuschirwan Peyman, Karlheinz Scheunemann, Jean-Marie Ruxer, Denis Carniato, Jean-Michel Lefrancois, Thomas Richard Gadek, Robert McDowell
  • Patent number: 5674863
    Abstract: A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: October 7, 1997
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Peter Barker, Thomas Gadek, Robert McDowell, Lawrence McGee, Todd Somers, Rob Webb, Kirk Robarge
  • Patent number: 5674865
    Abstract: A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: October 7, 1997
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Peter Barker, Thomas Gadek, Robert McDowell, Lawrence McGee, Todd Somers, Rob Webb, Kirk Robarge
  • Patent number: 5663166
    Abstract: A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: September 2, 1997
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Peter Barker, Thomas Gadek, Robert McDowell, Lawrence McGee, Todd Somers, Rob Webb, Kirk Robarge
  • Patent number: 5572188
    Abstract: An erectable and collapsible warning signal reflector assembly includes a pair of crossed arms that are pivotally connected to one another at their crossing point and are further attached to a vertical post stand at the same point. An elongated hollow box is used as a stand. The bottom of the vertical post is positioned into an opening in a top lid cover of the elongated box stand. When the crossed arms and post are rotated along the same plane, the entire assembly can be fit into the elongated box for storage purposes. Electrically powered lights are located on at least one side of each of the arms. The lights can be powered by a battery and switch inside each of the arms. Alternatively, the lights can be powered by an adapter plug that can be inserted into a conventional cigarette lighter. Alternatively, the lights can be reflector covers.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: November 5, 1996
    Inventor: Robert A. McDowell, II
  • Patent number: 5565449
    Abstract: A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: October 15, 1996
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Peter Barker, Thomas Gadek, Robert McDowell, Lawrence McGee, Todd Somers, Rob Webb, Kirk Robarge
  • Patent number: 5403836
    Abstract: A benzazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: May 6, 1993
    Date of Patent: April 4, 1995
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Robert McDowell, Thomas Gadek, Rob Webb
  • Patent number: 5250679
    Abstract: A benzodiazepinedione derivative which acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
    Type: Grant
    Filed: April 10, 1992
    Date of Patent: October 5, 1993
    Assignee: Genentech, Inc.
    Inventors: Brent Blackburn, Robert McDowell, Thomas Gadek, Peter Barker, Lawrence McGee, Rob Webb
  • Patent number: 4759606
    Abstract: A reflector assembly for use on the road by a vehicle driver near his or her stopped vehicle comprising three reflective arms crossing and pivoted to each other at the middle, and bases pivotally connected to two of the arms at one end of each. When the assembly is erected, the crossing arms are spread apart angularly and the bases hold their respective arms extending up diagonally. Wing nuts at the pivots releasably clamp the arms and bases in this position. After loosening the wing nuts, the user can collapse the reflector assembly to a folded position in which the arms are aligned one behind the other.
    Type: Grant
    Filed: January 14, 1987
    Date of Patent: July 26, 1988
    Inventor: Robert A. McDowell
  • Patent number: 4478052
    Abstract: An insulated receptacle for holding beverage cans or other food items in the front seat compartment of an automotive vehicle. The receptacle has hangers for releasably mounting it in the vehicle, an air inlet for connection to a flexible hose leading from an air vent connected to the vehicle's air conditioning/heating system, and an air outlet for passing air from the interior of the receptacle. Can support members in the receptacle present upwardly-facing recesses for snugly receiving beverage cans.
    Type: Grant
    Filed: September 23, 1983
    Date of Patent: October 23, 1984
    Inventor: Robert A. McDowell
  • Patent number: 4107789
    Abstract: The invention employs high volume air to form a cloud of coating material or material to be uniformly dispersed and conveys it to a plenum or common area of the receiving material which is coated. A mixer creates turbulence in the receiving material to turn up new receiving material to be coated. The invention has application to cement mixing, pigment and starch mixing, or even the mixing of atomized or vaporized fluid with on or more receiving materials to establish optimum surface connection for producing stronger cement or utilizing less materials for the same strength or optimizing the dispersion of the cloud introduced material with the receiving material.
    Type: Grant
    Filed: January 28, 1976
    Date of Patent: August 15, 1978
    Assignees: Bevil J. Kilgore, James H. Backus
    Inventor: Robert McDowell