Patents by Inventor Robert McKay

Robert McKay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070142254
    Abstract: The present invention relates to a storage system having (a) a container having multiple storage compartments; (b) at least one package of denture cleaning tablets provided in one of the three storage compartments; and (c) at least one additional denture cleaning resource provided in at least one other storage compartment, wherein the container is suitable for use as a tub for cleansing dentures.
    Type: Application
    Filed: December 1, 2006
    Publication date: June 21, 2007
    Inventors: Sandra Arce, Silvio DiMarchi, Brenda Williams-Halsey, Sheng-Fu Lee, Robert McKay, Lawrence Scanzillo
  • Publication number: 20070129269
    Abstract: A storage system is disclosed having (a) a case with three storage compartments provided in a tri-fold configuration; (b) at least one package of denture cleaning tablets provided in one of the three storage compartments; and (c) at least one additional denture cleaning resource provided in one of the three storage compartments.
    Type: Application
    Filed: December 2, 2005
    Publication date: June 7, 2007
    Inventors: Sandra Arce, Silvio DiMarchi, Brenda Williams-Halsey, Sheng-Fu Lee, Robert McKay, Lawrence Scanzillo
  • Publication number: 20070066557
    Abstract: Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides which have particular in vivo properties, targeted to nucleic acids encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for treatment of diseases are provided.
    Type: Application
    Filed: September 19, 2006
    Publication date: March 22, 2007
    Inventors: Brett Monia, Robert McKay, Susan Freier, Sanjay Bhanot, Lynnetta Watts
  • Publication number: 20060260832
    Abstract: An off-axis rotary joint (20) for selectively enabling communication of a signal (i.e., electrical and/or optical) between a housing (21) mounted for rotation about an axis (y-y) relative to a hollow shaft assembly (22) at all permissible relative angular displacements (e.g., 0°, 180°, 360°, 540°, 720°, etc.
    Type: Application
    Filed: April 18, 2006
    Publication date: November 23, 2006
    Inventor: Robert McKay
  • Publication number: 20060160760
    Abstract: Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise oligonucleotides, targeted to nucleic acid encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for diagnosis and treatment of diseases and conditions associated with expression of glucocorticoid receptor are provided.
    Type: Application
    Filed: August 18, 2005
    Publication date: July 20, 2006
    Applicant: Isis Pharmaceuticals, Inc.
    Inventors: Sanjay Bhanot, Robert McKay
  • Publication number: 20060160758
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CD40 ligand. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40 ligand. Methods of using these compounds for modulation of CD40 ligand expression and for treatment of diseases associated with expression of CD40 ligand are provided.
    Type: Application
    Filed: January 20, 2005
    Publication date: July 20, 2006
    Inventors: C. Bennett, Susan Freier, Brenda Baker, Brett Monia, Nicholas Dean, Hong Zhang, Susan Murray, Lex Cowsert, Madeline Butler, Robert McKay, Donna Ward, William Gaarde, Ian Popoff, Jacqueline Wyatt, Andrew Watt
  • Publication number: 20060154885
    Abstract: Compounds, compositions and methods are provided for modulating the expression of SLC26A2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SLC26A2. Methods of using these compounds for modulation of SLC26A2 expression and for diagnosis and treatment of disease associated with expression of SLC26A2 are provided.
    Type: Application
    Filed: March 4, 2005
    Publication date: July 13, 2006
    Inventors: C. Bennett, Brett Monia, Nicholas Dean, Xiaoxing Xu, Sanjay Bhanot, Brenda Baker, Susan Freier, Lex Cowsert, Robert McKay, Muthiah Manoharan, F. Dorr, Jon Holmlund, Alexander Borchers, Vickie Brown-Driver, Jacqueline Wyatt, Shin Flournoy, Elizabeth Ackermann, Hong Zhang, Andrew Watt, Eric Maracusson, Scott Cooper, Erich Koller, Loren Miraglia, William Ricketts, Kenneth Dobie, Tamara Sipes
  • Publication number: 20060084094
    Abstract: The present invention provides methods of identifying oligomeric compounds, such as siRNA and double-stranded RNA compounds, having bioactivity in vivo, and kits.
    Type: Application
    Filed: September 7, 2005
    Publication date: April 20, 2006
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: C. Bennett, Robert McKay, Brett Monia, Brenda Baker, Namir Sioufi, Richard Griffey, Balkrishen Bhat, Eric Swayze
  • Publication number: 20060025372
    Abstract: Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
    Type: Application
    Filed: August 1, 2005
    Publication date: February 2, 2006
    Inventors: Sanjay Bhanot, Lex Cowsert, Jacqueline Wyatt, Brett Monia, Madelline Butler, Robert McKay, Susan Freier, Kenneth Dobie
  • Publication number: 20060019920
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of MEKK4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MEKK4. Methods of using these compounds for modulation of MEKK4 expression and for treatment of diseases associated with expression of MEKK4 are provided.
    Type: Application
    Filed: July 11, 2005
    Publication date: January 26, 2006
    Inventors: C. Bennett, Susan Freier, Brett Monia, Nicholas Dean, Hong Zhang, Robert McKay, Donna Ward, William Gaarde, Jacqueline Wyatt, Andrew Watt, Rosanne Crooke, Mark Graham, Pamela Nero, Kenneth Dobie, Alexander Borchers, Eric Marcusson, Mark Roach
  • Publication number: 20060003953
    Abstract: Disclosed herein are compounds, compositions and methods for modulating the expression of a bone growth modulator in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
    Type: Application
    Filed: December 3, 2004
    Publication date: January 5, 2006
    Inventors: C. Bennett, Madeline Butler, Nicholas Dean, Kenneth Dobie, Joshua Finger, Ravi Jain, Robert McKay, Brett Monia, Kathleen Myers
  • Publication number: 20050221275
    Abstract: The present invention provides methods of identifying oligomeric compounds, such as siRNA and double-stranded RNA compounds, having bioactivity in vivo, and kits.
    Type: Application
    Filed: April 14, 2004
    Publication date: October 6, 2005
    Inventors: C. Bennett, Robert McKay, Brett Monia, Brenda Baker, Namir Sioufi
  • Publication number: 20050215504
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of sterol regulatory element-binding protein-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sterol regulatory element-binding protein-1. Methods of using these compounds for modulation of sterol regulatory element-binding protein-1 expression and for treatment of diseases associated with expression of sterol regulatory element-binding protein-1 are provided.
    Type: Application
    Filed: December 16, 2004
    Publication date: September 29, 2005
    Inventors: C. Bennett, Susan Freier, Nicholas Dean, Brett Monia, William Gaarde, James Karras, Hong Zhang, Robert McKay, Donna Ward, Lex Cowsert, Erich Koller, Jacqueline Wyatt, Mark Roach, Andrew Watt, Brenda Baker, Kenneth Dobie
  • Publication number: 20050186567
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of Peroxisome proliferator-activated receptor gamma. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Peroxisome proliferator-activated receptor gamma Methods of using these compounds for modulation of Peroxisome proliferator-activated receptor gamma expression and for treatment of diseases associated with expression of Peroxisome proliferator-activated receptor gamma are provided.
    Type: Application
    Filed: January 11, 2001
    Publication date: August 25, 2005
    Inventors: Robert McKay, Alexander Borchers, Brenda Baker
  • Publication number: 20050164209
    Abstract: The present invention provides methods of identifying an oligomeric compound having bioactivity in vivo, methods of identifying a small interfering RNA having bioactivity in vivo, and kits.
    Type: Application
    Filed: January 23, 2004
    Publication date: July 28, 2005
    Inventors: C. Bennett, Robert McKay, Brett Monia, Brenda Baker
  • Publication number: 20050095710
    Abstract: Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
    Type: Application
    Filed: December 9, 2004
    Publication date: May 5, 2005
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: Lex Cowsert, Jacqueline Wyatt, Susan Freier, Brett Monia, Madeline Butler, Robert McKay
  • Publication number: 20050074801
    Abstract: The present invention relates to novel chimeric oligomeric compounds having a plurality of alternating regions having either RNA like having northern or 3?-endo conformational geometry (3?-endo regions) or DNA like having southern or C2?-endo/O4?-endo conformational geometry. The oligomeric compounds of the present invention have shown reduction in mRNA levels in multiple in vitro and in vivo assay systems and are useful, for example, for investigative and therapeutic purposes.
    Type: Application
    Filed: September 8, 2004
    Publication date: April 7, 2005
    Inventors: Brett Monia, Madeline Butler, Robert McKay, Brenda Baker
  • Publication number: 20040266714
    Abstract: Compounds, compositions and methods are provided for modulating the expression of glucagon receptor. The compositions comprise oligonucleotides, targeted to nucleic acid encoding glucagon receptor. Methods of using these compounds for modulation of glucagon receptor expression and for diagnosis and treatment of disease associated with expression of glucagon receptor are provided.
    Type: Application
    Filed: April 27, 2004
    Publication date: December 30, 2004
    Inventors: Susan Freier, Kenneth W. Dobie, Robert McKay
  • Patent number: D531408
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: November 7, 2006
    Assignee: Warner-Lambert Company LLC
    Inventors: Sandra Arce, Silvio J. DiMarchi, Brenda Williams-Halsey, Sheng-Fu Lee, Robert McKay, Lawrence P. Scanzillo
  • Patent number: D498584
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: November 23, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Silvio J. DiMarchi, Robert McKay, Lawrence P. Scanzillo