Abstract: A spraying device for dispensing electrostatic liquid droplets includes a container holding a liquid at one end, and having a nozzle assembly with an aperture at another end. The nozzle assembly includes a longitudinal hollow tube terminating in a metallic structure. The metallic structure includes a metallic base plate having at least one aperture formed therein for fluid communication with the hollow tube. The longitudinal hollow tube includes an end inserted in the liquid. A charge accumulator disposed in the liquid accumulates electrostatic charges. A wire conductor between the base plate and the charge accumulator transfers the electrostatic charges from the liquid to the nozzle assembly.

Abstract: A spraying device for dispensing electrostatic liquid droplets includes a container holding a liquid at one end, and having a nozzle assembly with an aperture at another end. The nozzle assembly includes a longitudinal hollow tube terminating in a metallic structure. The metallic structure includes a metallic base plate having at least one aperture formed therein for fluid communication with the hollow tube. The longitudinal hollow tube includes an end inserted in the liquid. A charge accumulator disposed in the liquid accumulates electrostatic charges. A wire conductor between the base plate and the charge accumulator transfers the electrostatic charges from the liquid to the nozzle assembly.

Abstract: A method for accomplishing a plurality of combinatorial processes in parallel using a microelectronic and fluidic array (device array) having micron-sized reservoirs, connecting microchannels and reaction cells etched into a substrate. The device array has a top feedthru plate, a center distribution plate and a bottom cell plate. The top feedthru plate serves as a cover for the device array and contains apertures selectively positioned above the reservoirs located in the center distribution plate. The center distribution plate includes a plurality of micron sized reservoirs, microchannels, reservoir feeds, cell feeds and overflow feeds for the distribution of reagent fluids to the reaction cells located in the bottom cell plate. The detachable bottom cell plate serves as a microlaboratory tray of reaction cells. Once the proper reagents or other materials are introduced into the reaction cells, the bottom cell plate is decoupled from the device array and removed for incubation or analysis.

Abstract: Provided is a liquid dispensing device for delivering defined volumes comprising (a) a reagent fill channel, (b) one or more metering capillaries connected to the reagent fill channel and having an exit, and (c) one or more sources of gas connected to the reagent fill channel, wherein after filing the one or more metering capillaries the reagent fill channel can be drained of liquid while liquid is retained in the one or more metering capillaries, and the source of gas can be operated to eject the liquid in the metering capillaries.

Abstract: The invention provides, among other things, bead dispenser for holding a charged bead and selectively dispensing the bead, the dispenser comprising: (a) a feeder channel having a lower outlet; (b) a bead selection escapement with a depression having an outer lip and located below the first lower outlet such that a bead exiting the lower outlet comes to rest in the depression; (c) a dispenser channel descending from the level of the lip, wherein the lip impedes a bead situated on the bead selection escapement from entering the dispenser channel; and a first dispensing electrode for creating an electromagnetic potential to pull or push the bead over the rim and into the dispenser channel.

Abstract: A system and method for accomplishing a plurality of combinatorial processes in parallel comprising a microelectronic and fluidic array (device array) having micron-sized reservoirs, connecting microchannels and reaction cells etched into a substrate. The device array is supported by a station which serves to interface and perform electro-optic measurements of material in the reaction cells of the device array. The device array incorporates a modular configuration with three distinct layers or plates. The device array comprises a top feedthru plate, a center distribution plate and a bottom cell plate. The three plates are stacked vertically and coupled together to form a liquid-tight seal. Reservoirs, microchannels and reactions cells are controllably etched onto the plates using traditional semiconductor fabrication techniques. The top feedthru plate serves as a cover for the device array and contains apertures selectively positioned above the reservoirs located in the center distribution plate.

Abstract: The invention provides an apportioning system comprising a first apportioning chamber having a first outlet and fillable with liquid to a first defined level such that if liquid is added to fill the first apportioning chamber above the first defined level, then the extra fluid drains through the first outlet, an inlet channel that distributes liquid to the first apportioning chamber, and a first electrode-based pump for moving liquid in the first apportioning chamber out the first outlet.

Abstract: The invention provides electrode-based pumps and methods of operating such pumps. In one embodiment, the invention provides an electrode-based pump situated in a fluid channel comprising a first electrode and a second electrode, wherein the first and second electrodes have a diameter from about 25 microns to about 100 microns and are spaced from about 100 microns to about 2,500 microns apart. In another embodiment, the invention provides an electrode-based pump comprising a first electrode, second electrode and third electrode.

Abstract: The invention provides a plate having a plurality uniformly sized reaction cells formed in its upper surface, wherein the density of the reaction cells is at least about 10 cells per cm.sup.2. Preferably, the area of each of the openings of the reaction cells is no more than about 55% of the area defined by the multiplication product of (1) the pitch between reaction cells in separate rows and (2) the pitch between reaction cells in separate columns.

Abstract: A full N-key rollover capability information entry device includes first and second sets of intersecting light guides oriented at an angle to one another which may comprise a mesh of waveguides that together form a self-supporting planar sheet of a substantially transparent material at the wavelength of light introduced into one end of at least one of the first and second sets of light guides. This permits each intersection to comprise a common portion of both a light guide of the first set and a light guide of the second set that intersect at that intersection. Detection of changes in the intensity of the light in at least one of the sets of light guides in response to key actuation that blocks a portion of the light at a certain intersection is indicative of that actuated key.

Abstract: An electron gun apparatus comprises a cathode subassembly which is movably mounted relative to a fixedly mounted and registered grid/anode subassembly to permit mechanical adjustment of the cathode with respect to the grid/anode subassembly. An evacuated chamber, including resilient bellows interconnecting the movably mounted cathode assembly to the fixedly mounted grid/anode subassembly for permitting the mechanical adjustment, houses the cathode and the grid/anode subassemblies. Means are provided for electrical energization of the cathode, the grid, and the anode. According to a further feature of the invention, the cathode comprises a line filament, and the grid and the anode are slotted for providing an elongated line image.