Patents by Inventor Robert Tigelaar

Robert Tigelaar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES
    Publication number: 20220280562
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: November 18, 2021
    Publication date: September 8, 2022
    Inventors: Günter BAUER, Justin DUCKWORTH, Robert TIGELAAR, Richard EDELSON, Michael GIRARDI, Karsten HENCO, Adrian HAYDAY
  • METHOD FOR OBTAINING IMMUNO-SUPPRESSIVE DENDRITIC CELLS
    Publication number: 20220259556
    Abstract: The present invention relates to methods for producing immuno-suppressive dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from autoimmune diseases, hypersensitivity diseases, rejection on solid-organ transplantation and/or Graft-versus-Host disease.
    Type: Application
    Filed: October 21, 2021
    Publication date: August 18, 2022
    Inventors: Karsten HENCO, Gunter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS
    Publication number: 20220112462
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: October 26, 2021
    Publication date: April 14, 2022
    Inventors: Karsten HENCO, Günter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • Method for obtaining globally activated monocytes
    Patent number: 11179417
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: November 23, 2021
    Assignees: Transimmune AG, Yale University
    Inventors: Gunter Bauer, Justin Duckworth, Robert Tigelaar, Richard Edelson, Michael Girardi, Karsten Henco, Adrian Hayday
  • METHOD FOR OBTAINING GLOBALLY ACTIVATED MONOCYTES
    Publication number: 20170128490
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: July 3, 2015
    Publication date: May 11, 2017
    Inventors: GUNTER BAUER, JUSTIN DUCKWORTH, ROBERT TIGELAAR, RICHARD EDELSON, MICHAEL GIRARDI, KARSTEN HENCO, ADRIAN HAYDAY
  • METHOD FOR OBTAINING IMMUNO-STIMULATORY DENDRITIC CELLS
    Publication number: 20160298082
    Abstract: The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.
    Type: Application
    Filed: January 2, 2014
    Publication date: October 13, 2016
    Inventors: Karsten HENCO, Gunter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • METHOD FOR OBTAINING IMMUNO-SUPPRESSIVE DENDRITIC CELLS
    Publication number: 20160130552
    Abstract: The present invention relates to methods for producing immuno-suppressive dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from autoimmune diseases, hypersensitivity diseases, rejection on solid-organ transplantation and/or Graft-versus-Host disease.
    Type: Application
    Filed: January 2, 2014
    Publication date: May 12, 2016
    Inventors: Karsten HENCO, Gunter BAUER, Justin DUCKWORTH, Adrian HAYDAY, Richard EDELSON, Robert TIGELAAR, Michael GIRARDI
  • Anti-inflammatory and wound healing effects of lymphoid thymosin beta-4
    Publication number: 20060264360
    Abstract: The invention relates to a method of treating inflammatory conditions in a subject comprising administering to a subject a composition comprising a lymphoid thymosin-?4 polypeptide or a functional lymphoid thymosin-?4polypeptide variant. The invention also provides a method of promoting wound healing in a subject comprising administering to the subject a composition comprising a lymphoid thymosin-?4 polypeptide or a functional lymphoid thymosin-?4polypeptide variant. The invention also relates to methods of treating the above mentioned conditions in a subject comprising administering to the subject a nucleic acid encoding a lymphoid thymosin-?4 polypeptide or a functional lymphoid thymosin-?4 polypeptide variant. The invention also relates to pharmaceutical compositions comprising a lymphoid thymosin-?4 polypeptide or a functional lymphoid thymosin-?4polypeptide variant, or salt thereof, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 11, 2003
    Publication date: November 23, 2006
    Applicants: Yale University Office Of Cooperstive Research, King's College London
    Inventors: Michael Girardi, Robert Tigelaar, Michael Sherling, John Shires, Adrian Hayday, Efatathios Theodoridis