Patents by Inventor Robert Z. LUO

Robert Z. LUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED DIHYDROPYRANOPYRIMIDINE COMPOUNDS AS KRAS INHIBITORS
    Publication number: 20220112204
    Abstract: The present disclosure relates to novel compounds that inhibit KRAS G120, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and conditions.
    Type: Application
    Filed: October 13, 2021
    Publication date: April 14, 2022
    Applicant: ACCUTAR BIOTECHNOLOGY INC.
    Inventors: Jie FAN, Yimin QIAN, Wei HE, Robert Z. LUO
  • Sodium channel modulators for the treatment of pain
    Patent number: 10179781
    Abstract: Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I: In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 15, 2019
    Inventors: Olga Babich, Robert Z. Luo, Yanlin Wang-Fischer, David J. Palling, Srinivasan P. Venkatachalan
  • SELECTIVE NaV1.7 INHIBITORS FOR THE TREATMENT OF DIABETES
    Publication number: 20170304306
    Abstract: Provided herein are methods for treating or preventing prediabetes or diabetes, or maintaining or lowering blood or plasma glucose or maintaining or lowering blood or plasma glycated hemoglobin comprising administering to a subject in need thereof a therapeutically effective amount of a compound selectively inhibiting NaV1.7. In particular, provided herein are processes for the preparation of and intermediates used in the preparation of compounds selectively inhibiting NaV 1.
    Type: Application
    Filed: September 8, 2015
    Publication date: October 26, 2017
    Applicant: CHROMOCELL CORPORATION
    Inventors: Yanlin WANG-FISCHER, Olga BABICH, Tina GARYANTES, Robert Z. LUO, Srinivasan P. Venkatachalan
  • Sodium channel modulators for the treatment of pain and diabetes
    Patent number: 9458118
    Abstract: Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I or compounds of Formula I?: In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain and diabetes.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: October 4, 2016
    Assignee: Chromocell Corporation
    Inventors: Olga Babich, Tina Garyantes, Robert Z. Luo, David J. Palling, Srinivasan P. Venkatachalan, Yanlin Wang-Fischer
  • SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN AND DIABETES
    Publication number: 20160221974
    Abstract: Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I or compounds of Formula I?: In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain and diabetes.
    Type: Application
    Filed: September 9, 2014
    Publication date: August 4, 2016
    Applicant: CHROMOCELL CORPORATION
    Inventors: Olga BABICH, Tina GARYANTES, Robert Z. LUO, David J. PALLING, Srinivasan P. VENKATACHALAN, Yanlin WANG-FISCHER
  • SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN AND DIABETES
    Publication number: 20160130239
    Abstract: Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I or compounds of Formula I?: In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain and diabetes.
    Type: Application
    Filed: January 13, 2016
    Publication date: May 12, 2016
    Applicant: CHROMOCELL CORPORATION
    Inventors: Olga BABICH, Tina GARYANTES, Robert Z. LUO, David J. PALLING, Srinivasan P. VENKATACHALAN, Yanlin WANG-FISCHER
  • SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN
    Publication number: 20160046617
    Abstract: Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I: In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 18, 2016
    Applicant: CHROMOCELL CORPORATION
    Inventors: Olga BABICH, Robert Z. LUO, Yanlin WANG-FISCHER, David J. PALLING, Srinivasan P. VENKATACHALAN