Patents by Inventor Roberto Droghini

Roberto Droghini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING 2-AMINOTHIAZOLE-5-AROMATIC CARBOXAMIDES AS KINASE INHIBITORS
    Publication number: 20090149650
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: December 23, 2008
    Publication date: June 11, 2009
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John D. Dimarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Publication number: 20060004067
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: July 29, 2005
    Publication date: January 5, 2006
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John DiMarco, Michael Galella, Ramakrishnan Chidambaram
  • Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
    Publication number: 20050215795
    Abstract: The invention relates to processes for preparing compounds having the formula, and crystalline forms thereof, wherein Ar is aryl or heteroaryl, L is an optional alkylene linker, and R2, R3, R4, and R5, are as defined in the specification herein, which compounds are useful as kinase inhibitors, in particular, inhibitors of protein tyrosine kinase and p38 kinase.
    Type: Application
    Filed: February 4, 2005
    Publication date: September 29, 2005
    Inventors: Bang-Chi Chen, Roberto Droghini, Jean Lajeunesse, John Dimarco, Michael Galella, Ramakrishnan Chidambaram
  • N-substituted 2-azetidinones
    Patent number: 6008347
    Abstract: The present invention provides novel cis-N-iminomethyl-3,4-disubstituted-2-azetidinones, and their use in the preparation of N-acyl-2-azetidinones, intermediates in the semi-synthesis of taxol and taxol derivatives.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: December 28, 1999
    Assignee: Bristol-Myers Squibb Company
    Inventors: Allan W. Rey, Purushotham Vemishetti, Roberto Droghini
  • N-substituted 2-azetidinones
    Patent number: 5412092
    Abstract: Novel cis compound having the formula: ##STR1## wherein R.sup.1 is alkyl, haloalkyl, cycloalkyl, aryl or a carbohydrate derivative; X is O, N, S, C(O)O or a direct bond; and R.sup.2 is aryl, substituted aryl or heteroaryl are useful in the synthesis of taxol and taxol derivatives.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: May 2, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Allan W. Rey, Purushotham Vemishetti, Roberto Droghini