Abstract: Arterial perfusion cannula, for extracorporeal circulation and related uses. The distal end may be inserted into the ascending aorta, or into the femoral artery and the other part is to be connected to a cardio-pulmonary machine, comprising a multi-channel catheter formed by at least three pathways two of which correspond to the inlet of blood flow, provided with openings which, being interconnectable to the aortic vessel, are located in two different points of the cannula's distal end, the third pathway channelizing a fluid feeding at least one inflatable balloon, located between said interconnecting openings, as an arterial occlusive element adjustable against the inner vessel walls.