Patents by Inventor Rodney D. Bush
Rodney D. Bush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5492690Abstract: The subject invention relates to pharmaceutical compositions comprising a safe and effective amount of a compound having the structure: ##STR1## wherein n is 3 or 4; each R is independently alkyl or alkoxy; and R' is C.sub.1 C.sub.20 alkyl; and a pharmaceutically-acceptable topical carrier.The subject invention also relates to methods for preventing damage to skin, without markedly sensitizing the skin, by topically applying a safe and effective amount of such compounds to the skin.Type: GrantFiled: March 3, 1994Date of Patent: February 20, 1996Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush
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Patent number: 5487884Abstract: The present invention involves photoprotective compositions which are useful for topical application to prevent damage to skin caused by acute or chronic exposure to ultraviolet light comprising chelating agents. Also involved are compositions comprising chelating agents together with anti-inflammatory agents, sunscreening agents, and/or radical scavenging agents. Methods for using such compositions to prevent damage to skin caused by acute or chronic exposure to ultraviolet light are also involved.Type: GrantFiled: July 1, 1993Date of Patent: January 30, 1996Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Rodney D. Bush, Ranjit Chatterjee
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Patent number: 5462963Abstract: The present invention involves photoprotective compositions which are useful for topical application to prevent damage to skin caused by acute or chronic exposure to ultraviolet light comprising chelating agents having the structure: ##STR1## wherein each --R.sup.1 is independently selected from the group consisting of alkyl, aryl, heteroaryl and heterocycle, or the --R.sup.1 's are covalently bonded together to form a cyclic alkyl or heterocyclic ring; --R.sup.2 and --R.sup.3 are --OR.sup.4, in which case there is no bond or a polar bond between --R.sup.2 and the nitrogen covalently bonded to --R.sup.3, each --R.sup.4 being independently selected from the group consisting of hydrogen, alkyl and aryl, except that both --R.sup.4 's are not methyl when both --R.sup.1 's are furyl; or --R.sup.2 is --O-- and is covalently bonded to the nitrogen which is covalently bonded to --R.sup.3, and --R.sup.3 is --O-- (there being a + charge on the nitrogen to which it is bonded) or nil;wherein the .alpha.Type: GrantFiled: August 2, 1991Date of Patent: October 31, 1995Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Donald L. Bissett
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Patent number: 5456904Abstract: The subject invention relates to methods and compositions comprising: a) from about 0.1% to about 5% of a compound having the structure selected from the group consisting of: ##STR1## wherein each R is independently selected from the group consisting of hydrogen, alkyl, and aryl; each R' is independently selected from the group consisting of hydrogen, alkoxy, and alkyl; Z and Z' are independently selected from the group consisting of NH, O, and CH.sub.2 such that when Z or Z' is NH, the other is not O; or a pharmaceutically acceptable salt of any of the aforementioned compounds; and b) a pharmaceutically-acceptable topical carrier.Type: GrantFiled: June 28, 1993Date of Patent: October 10, 1995Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush
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Patent number: 5441727Abstract: The present invention provides deodorant compositions for controlling malodor from perspiration comprising a safe an effective amount of a 1,3-diketone compound having the general formula: ##STR1## wherein each W is independently selected from the group consisting of O, S and (CH.sub.2).sub.n, wherein n=1-3; and each X is independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted alkyl having from about 1 to about 5 carbon atoms, or two X moieties are covalently bonded to form a substituted or unsubstituted alkyl, heteroalkyl, aryl or heteroaryl ring having from about 3 to about 12 atoms including from 0 to about 3 heteroatoms in the ring; and a topical carrier; whereby the composition is suitable for topical application to the skin or to articles of clothing worn in the vicinity of the skin.Type: GrantFiled: July 30, 1990Date of Patent: August 15, 1995Assignee: The Procter & Gamble CompanyInventors: Ranjit Chatterjee, Rodney D. Bush
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Patent number: 5439954Abstract: The subject invention relates to pharmaceutical compositions comprising a safe and effective amount of a compound having the structure: ##STR1## wherein each R is alkyl or hydrogen, at least two being alkyl; R' is hydrogen, alkyl or aryl; R" is alkyl or halo; and each X is independently oxygen or sulfur; and a pharmaceutically-acceptable carrier. The subject invention also relates to methods for preventing damage to skin by topically applying a safe and effective amount of such compounds to the skin.Type: GrantFiled: October 11, 1991Date of Patent: August 8, 1995Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush
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Photoprotection compositions comprising a radical scavenging compound and an anti-inflammatory agent
Patent number: 5384115Abstract: Disclosed are photoprotective compositions comprising a radical scavenging agent and an anti-inflammatory agent which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of a radical scavenging agent, an anti-inflammatory agent, and a sunscreen are also disclosed.Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: August 20, 1993Date of Patent: January 24, 1995Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Rodney D. Bush, Ranjit Chatterjee -
Patent number: 5364617Abstract: The present invention involves photoprotective compositions which are useful for topical application to prevent damage to skin caused by acute or chronic exposure to ultraviolet light comprising chelating agents having the formula ##STR1## wherein --R.sup.1 and --R.sup.2 are independently selected from the group consisting of alkyl, aryl, and heteroaryl, or R.sup.1 and R.sup.2 may be covalently bonded together to form a cyclic alkyl; --M is selected from the group consisting of =0, =S, --SR.sup.4 and --OR.sup.4 (when --M is --OR.sup.4 or --SR.sup.4, there is a hydrogen bonded to the carbon to which --M is bonded); --R.sup.4 is selected from the group consisting of hydrogen, alkyl, aryl and heteroaryl; --R.sup.3 is selected from the group consisting of hydrogen, alkyl, aryl and heteroaryl; --R.sup.6 is selected from the group consisting of hydrogen alkyl, aryl and heteroaryl; and i is selected from the group consisting of one and zero.Type: GrantFiled: November 9, 1992Date of Patent: November 15, 1994Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Donald L. Bissett, Ranjit Chatterjee
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Patent number: 5028415Abstract: The present invention relates to oral compositions, such as dentifrices, toothpastes and mouthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.Type: GrantFiled: December 16, 1988Date of Patent: July 2, 1991Assignee: The Procter & Gamble CompanyInventors: James J. Benedict, Rodney D. Bush, Richard J. Sunberg
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Patent number: 4954332Abstract: Disclosed are pharmaceutical compositions comprising tocopherol sorbate and an anti-inflammatory agent which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of tocopherol sorbate, an anti-inflammatory agent, and a sunscreen are also disclosed.Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: June 26, 1989Date of Patent: September 4, 1990Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Rodney D. Bush, Ranjit Chatterjee
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Patent number: 4847071Abstract: Disclosed are pharmaceutical compositions comprising tocopherol sorbate and an anti-inflammatory agent which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of tocopherol sorbate, an anti-inflammatory agent, and a sunscreen are also disclosed.Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: October 22, 1987Date of Patent: July 11, 1989Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Rodney D. Bush, Ranjit Chatterjee
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Patent number: 4847072Abstract: Disclosed are pharmaceutical compositions comprising tocopherol sorbate which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of tocopherol sorbate and sunscreening agents are also disclosed.Also disclosed is a method for using these compositions topically, to prevent damage to skin caused by acute or chronic UV exposure.Type: GrantFiled: October 22, 1987Date of Patent: July 11, 1989Assignee: The Procter & Gamble CompanyInventors: Donald L. Bissett, Rodney D. Bush
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Patent number: 4846650Abstract: The present invention relates to oral compositions, such as dentrifices, toothpastes and mounthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.Type: GrantFiled: August 17, 1987Date of Patent: July 11, 1989Assignee: The Procter & Gamble CompanyInventors: James J. Benedict, Rodney D. Bush, Richard J. Sunberg
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Patent number: 4663071Abstract: Provided herein are ether carboxylate builder compositions comprising a combination of tartrate monosuccinic acid (or salts thereof) and tartrate disuccinic acid (or salts thereof). Such mixtures can be prepared by reacting water-soluble, mixed maleic acid salts with mixed tartaric acid salts. Both components of the resulting ether carboxylate mixture act as sequestering agents and are useful as detergency builders. Detergent and laundry additive compositions incorporating these ether carboxylates can be prepared without use of detergent builder components containing phosphorus or nitrogen.Type: GrantFiled: January 30, 1986Date of Patent: May 5, 1987Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Daniel S. Connor, Stephen W. Heinzman, Larry N. Mackey
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Patent number: 4654159Abstract: Ether hydroxypolycarboxylates prepared from epoxysuccinates by treatment with an alkaline calcium compound are disclosed. These compounds act as sequestering agents and are useful as detergency builders. Detergent compositions incorporating the ether hydroxypolycarboxylates can be prepared without use of detergent builder components containing phosphorus or nitrogen.Type: GrantFiled: July 11, 1985Date of Patent: March 31, 1987Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Stephen W. Heinzman
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Patent number: 4566984Abstract: Novel ether carboxylates prepared from ketomalonate esters and diene compounds are disclosed. Detergent compositions incorporating the ether carboxylates can be prepared without use of phosphorus-containing detergent builder materials.Type: GrantFiled: November 16, 1984Date of Patent: January 28, 1986Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush
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Patent number: 4506048Abstract: A class of polymer precursor materials, which, under appropriate conditions, react to form cross-linked polymers, is disclosed. These materials contain a backbone segment, such as polyacrylate, having pendant therefrom mono- or disubstituted olefinic groups, such as vinyl itaconate, having specific polymerization rates. This class of materials, especially when coupled with specifically-defined oxygen-activated catalyst systems, provide paint and plastic compositions which exhibit excellent film formation, strength and durability characteristics.Type: GrantFiled: October 31, 1983Date of Patent: March 19, 1985Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Medford D. Robbins
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Patent number: 4438246Abstract: 4-Vinyl-2-methylenebutanedioic acid and its esters, as well as amide and nitrile analogs of these compounds, are diclosed. These compounds are capable of undergoing a rapid free radical cyclopolymerization reaction. The compounds, themselves, may be used as film-formers (for example, in paints or plastics) or may be used as groups pendant from a backbone, especially a low molecular weight backbone, to form other, more complex film-forming polymer precursor materials.Type: GrantFiled: May 27, 1983Date of Patent: March 20, 1984Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush
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Patent number: 4427835Abstract: A class of polymer precursor materials, which, under appropriate conditions, react to form cross-linked polymers, is disclosed. These materials contain a backbone segment, such as polyacrylate, having pendant therefrom mono- or disubstituted olefinic groups, such as vinyl itaconate, having specific polymerization rates. This class of materials, especially when coupled with specifically-defined oxygen-activated catalyst systems, provide paint and plastic compositions which exhibit excellent film formation, strength and durability characteristics.Type: GrantFiled: August 7, 1981Date of Patent: January 24, 1984Assignee: The Procter & Gamble CompanyInventors: Rodney D. Bush, Medford D. Robbins
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Patent number: 4400531Abstract: 4-Vinyl-2-methylenebutanedioic acid and its esters, as well as amide and nitrile analogs of these compounds, are disclosed. These compounds are capable of undergoing a rapid free radical cyclopolymerization reaction. The compounds, themselves, may be used as film-formers (for example, in paints or plastics) or may be used as groups pendant from a backbone, especially a low molecular weight backbone, to form other, more complex film-forming polymer precursor materials.Type: GrantFiled: August 7, 1981Date of Patent: August 23, 1983Assignee: The Procter & Gamble CompanyInventor: Rodney D. Bush