Abstract: A machine and method for filling a container through an opening therein. The machine includes a machine frame defining a container conveying zone through which a container loaded into the machine moves during a filling operation. A container sterilizing assembly is mounted on the machine frame and defines a sterilizing station in the conveying zone, the sterilizing assembly being operable to aseptically sterilize the container, at least in a region incorporating the opening, when positioned at the sterilizing station. A container filling assembly is also mounted on the machine frame and defines a container filling station in the conveying zone, the filling assembly being operable to receive the sterilized container and fill the container through the opening therein with a product while maintaining at least the opening region of the container in an aseptic condition.