Patents by Inventor Roger Sik Yin FOO

Roger Sik Yin FOO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220227822
    Abstract: The invention relates to an isolated polypeptide encoded by Sghrt and related uses. In addition, methods of assessing a heart function, treating impaired heart function by inhibiting Sghrt, identifying a potential drug for treating impaired heart function, and dedifferentiating and/or proliferating a heart cell by inhibiting Sghrt are claimed.
    Type: Application
    Filed: February 12, 2020
    Publication date: July 21, 2022
    Inventors: Roger Sik Yin FOO, Dang Vinh DO
  • Publication number: 20200080081
    Abstract: The invention relates to inhibitors of Sghrt and/or Gas5 lincRNAs, in particular to polynucleotides complementary to coding and non-coding sequences of said lincRNAs, and methods of producing said inhibitors. Also disclosed are the use of the afore agents to proliferate, regenerate or dedifferentiate a heart cell; methods for preventing and treating cardiac disease using the afore agents; and a prognostic or diagnostic assay to assess the regenerative or proliferative capacity of heart tissue before, after or during a cardiac treatment regimen, comprising determining the presence or amount of Sghrt and/or Gas5 lincRNAs. The present disclosure also relates to a method for screening for a therapeutic agent that can be used to treat or prevent a heart disorder, comprising analysing the functional expression and/or expression level of Sghrt and/or Gas5 lincRNAs in the presence and in the absence of the therapeutic agent.
    Type: Application
    Filed: December 14, 2017
    Publication date: March 12, 2020
    Applicant: Agency for Science, Technology and Research
    Inventors: Kelvin Zhenwei SEE, Roger Sik Yin FOO