Patents by Inventor Roland Alexander Pache

Roland Alexander Pache has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11891645
    Abstract: The present invention relates to serine protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease derived from a strain of Meripilus giganteus belonging to the S53 family. The varinats according to the invention have in particular increased stability, e.g., increased thermo-stability, increased specific activity, and/or increased expression levels, compared to the parent protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: February 6, 2024
    Assignee: NOVOZYMES A/S
    Inventors: Dorte M. K. Klitgaard, Roland Alexander Pache, Martin Gudman, Anders G. Sandström
  • Publication number: 20230295591
    Abstract: Disclosed is variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Application
    Filed: January 11, 2023
    Publication date: September 21, 2023
    Applicant: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Dorte Marie Koefoed Klitgaard, Christian Isak Joergensen, Lars Giger
  • Publication number: 20230287380
    Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Application
    Filed: April 18, 2023
    Publication date: September 14, 2023
    Applicant: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Lars Giger
  • Patent number: 11732220
    Abstract: Cleaning compositions may include novel dispersin variants having improved properties relative to the parent dispersin. Such properties may include one or more of the following; wash performance, stability e.g. detergent and/or storage stability. The cleaning compositions may be suitable for use in cleaning processes and include detergent compositions, such as laundry compositions and dish wash compositions, including hand wash and automatic dish wash compositions.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: August 22, 2023
    Assignee: Henkel AG & Co. KGaA
    Inventors: Mirko Weide, Susanne Wieland, Lars Henrik Oestergaard, Annette Helle Johansen, Steffen Danielsen, Roland Alexander Pache, Johanne Moerch Jensen, Frank Winther Rasmussen, Martin Gudmand, Kasper Damgaard Tidemand
  • Publication number: 20230220366
    Abstract: The present invention relates to novel lactase variants having improved properties relative to the parent lactase, such as decreased galactose inhibition or increased galactose inhibition. The variants of the invention are suitable for production of dairy products, such as low-lactose dairy products or lactose-free dairy products. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the lactase variants of the invention.
    Type: Application
    Filed: February 23, 2021
    Publication date: July 13, 2023
    Applicant: Novozymes A/S
    Inventors: Roland Alexander Pache, Anders Gunnar Sandstrom, Jan Kjoelhede Vester, Henrik Friis-Madsen, Dorota Nissen
  • Publication number: 20230193327
    Abstract: The present invention relates to serine protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease derived from a strain of Meripilus giganteus belonging to the S53 family. The varinats according to the invention have in particular increased stability, e.g., increased thermo-stability, increased specific activity, and/or increased expression levels, compared to the parent protease. The present invention also relates to polynucleotides encoding the variants; nucleic N acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: July 14, 2017
    Publication date: June 22, 2023
    Applicant: NOVOZYMES A/S
    Inventors: Dorte M.K. Klitgaard, Roland Alexander Pache, Martin Gudman, Anders G. Sandström
  • Publication number: 20230183667
    Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.
    Type: Application
    Filed: October 25, 2022
    Publication date: June 15, 2023
    Applicant: Novozymes A/S
    Inventors: Annette Helle Johansen, Steffen Danielsen, Frank Winther Rasmussen, Peter Kamp Hansen, Roland Alexander Pache
  • Patent number: 11661592
    Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: May 30, 2023
    Assignee: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Lars Giger
  • Publication number: 20230159905
    Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.
    Type: Application
    Filed: November 3, 2022
    Publication date: May 25, 2023
    Applicant: Novozymes A/S
    Inventors: Annette Helle Johansen, Steffen Danielsen, Frank Winther Rasmussen, Peter Kamp Hansen, Roland Alexander Pache
  • Patent number: 11566239
    Abstract: Disclosed is variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: January 31, 2023
    Assignee: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Dorte Marie Koefoed Klitgaard, Christian Isak Joergensen, Lars Giger
  • Publication number: 20220364138
    Abstract: The present invention relates to polypeptide variants and methods for obtaining variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 6, 2020
    Publication date: November 17, 2022
    Applicant: Novozymes A/S
    Inventors: Lars Henrik Oestergaard, Annette Helle Johansen, Steffen Danielsen, Roland Alexander Pache, Johanne Moerch Jensen, Frank Winther Rasmussen, Martin Gudmand, Kasper Damgaard Tidemand
  • Patent number: 11499144
    Abstract: The present invention relates to xylanase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; compositions comprising the xylanase variants and methods of using the variants.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: November 15, 2022
    Assignee: Novozymes A/S
    Inventors: Annette Helle Johansen, Steffen Danielsen, Frank Winther Rasmussen, Peter Kamp Hansen, Roland Alexander Pache
  • Patent number: 11447763
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: September 20, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben P. Friis, Jens E. Nielsen, Roland Alexander Pache
  • Publication number: 20220186151
    Abstract: Disclosed are variants of a glycoside hydrolase having improved stability, e.g., in the presence of a protease, and the use of such variants in detergent applications, such as laundry or dish wash.
    Type: Application
    Filed: April 8, 2020
    Publication date: June 16, 2022
    Applicant: Novozymes A/S
    Inventors: Lars Giger, Frank Winther Rasmussen, Svend Gunnar Kaasgaard, Lars Anderson, Kenneth Jensen, Roland Alexander Pache, Dorte Marie Koefoed Klitgaard, Mette Louise Dissing Overgaard, Christian I. Joergensen
  • Publication number: 20220090041
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 24, 2022
    Applicant: Novozymes A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki-Hashizume, Yuma Kurakata, Esben Peter Friis, Jens Erik Nielsen, Roland Alexander Pache
  • Publication number: 20210363510
    Abstract: Disclosed is variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Application
    Filed: April 12, 2019
    Publication date: November 25, 2021
    Applicant: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Dorte Marie Koefoed Klitgaard, Christian Isak Joergensen, Lars Giger
  • Publication number: 20210317387
    Abstract: Cleaning compositions may include novel dispersin variants having improved properties relative to the parent dispersin. Such properties may include one or more of the following; wash performance, stability e.g. detergent and/or storage stability. The cleaning compositions may be suitable for use in cleaning processes and include detergent compositions, such as laundry compositions and dish wash compositions, including hand wash and automatic dish wash compositions.
    Type: Application
    Filed: March 29, 2021
    Publication date: October 14, 2021
    Inventors: Mirko WEIDE, Susanne WIELAND, Lars Henrik OESTERGAARD, Annette Helle JOHANSEN, Steffen DANIELSEN, Roland Alexander PACHE, Johanne Moerch JENSEN, Frank Winther RASMUSSEN, Martin GUDMAND, Kasper Damgaard TIDEMAND
  • Publication number: 20210139876
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben P. Friis, Jens E. Nielsen, Roland Alexander Pache
  • Patent number: 10927361
    Abstract: The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of Meripilus giganteus. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parent Meripilus giganteus protease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: February 23, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Keiichi Ayabe, Tomoko Matsui, Aki Tomiki, Yuma Kurakata, Esben P. Friis, Jens E. Nielsen, Roland Alexander Pache
  • Publication number: 20210047628
    Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
    Type: Application
    Filed: April 12, 2019
    Publication date: February 18, 2021
    Applicant: Novozymes A/S
    Inventors: Svend Gunnar Kaasgaard, Frank Winther Rasmussen, Roland Alexander Pache, Lars Anderson, Mette Louise Dissing Overgaard, Thomas Agersten Poulsen, Lars Giger