Patents by Inventor Roland Callens

Roland Callens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020058784
    Abstract: Ureins are obtained by reaction, in basic medium, between an N&ohgr;-(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.
    Type: Application
    Filed: September 4, 2001
    Publication date: May 16, 2002
    Inventors: Roland Callens, Georges Blondeel, Marc Anteunis, Frank Becu
  • Patent number: 6310178
    Abstract: Ureins are obtained by reaction, in basic medium, between an N&ohgr;-(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: October 30, 2001
    Assignee: Solvay, S.A.
    Inventors: Roland Callens, Georges Blondeel, Marc Anteunis, Frank Becu
  • Patent number: 6060586
    Abstract: Ureins are obtained by reaction, in basic medium, between an N.sup..omega. -(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: May 9, 2000
    Assignee: Solvay (Societe Anonyme)
    Inventors: Roland Callens, Georges Blondeel, Marc Anteunis, Frank Becu
  • Patent number: 5965770
    Abstract: Compounds having the general formula: ##STR1## in which R3 represents an aryl group which is unsubstituted or substituted by one or more alkyl groups containing 1 to 4 carbon atoms; R4 represents a hydrogen atom, a group for protecting the amino functional group, an amino acid or a peptide some of whose functional groups are optionally substituted by a protecting group or by an activating group; R5 represents a hydroxy group, a halogen atom, a group for protecting the carboxyl functional group, an activating group, an amino group, an amino acid or a peptide some of whose functional groups are optionally substituted by a protecting group or by an activating group; and n is an integer from 1 to 10.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: October 12, 1999
    Assignee: Solvay
    Inventors: Marc Anteunis, Frank Becu, Roland Callens, Georges Blondeel
  • Patent number: 5770692
    Abstract: Method of synthesising peptides containing one or more amino acid residues bearing an N-carbamoyl functional group, by aminolysis of N-aryloxycarbonyl derivatives, which are excellent synthesis intermediates for the preparation of various peptides containing amino acid residues bearing a ureino group, such as citrulline, homocitrulline, 2-amino-4-ureidobutyric residues.
    Type: Grant
    Filed: June 22, 1994
    Date of Patent: June 23, 1998
    Inventors: Marc Anteunis, Frank Becu, Roland Callens, Georges Blondeel
  • Patent number: 5506362
    Abstract: An .alpha.-amino acid amide is prepared by reaction of an N.sup..alpha. -aryloxycarbonylamino acid with a compound containing a free amino group. This process makes it possible readily to prepare peptides, by direct reaction between the carboxyl group of the N.sup..alpha. -aryloxycarbonyl derivative of an amino acid and the free amino group of a second amino acid or of a peptide fragment, without requiring protection of the carboxyl function of the second amino acid or of the peptide fragment, nor a coupling agent nor a deprotection step.
    Type: Grant
    Filed: June 9, 1994
    Date of Patent: April 9, 1996
    Assignee: Solvay (Societe Anonyme)
    Inventors: Roland Callens, Georges Blondeel
  • Patent number: 5262567
    Abstract: A compound useful in the synthesis of peptides containing arginine, and including a guanidine group and an unsubstituted tetraphenylborate ion, and having the formula: ##STR1## wherein A is a hydrogen atom, an amino acid group which is linked by a peptide bond and which may be substituted, a peptide radical which is linked by a peptide bond and which may be substituted, or an aliphatic or aromatic radical effective as a protecting group or an activating group, and wherein Y is an hydroxyl group, a halogen atom, an amino group, an amino acid group which is linked by a peptide bond and which may be substituted, a peptide radical which is linked by a peptide bond and which may be substituted, or an aliphatic or aromatic radical effective as a protecting group or an activating group.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: November 16, 1993
    Assignee: Solvay & Cie (Societe Anonyme)
    Inventors: Roland Callens, Andre Collin
  • Patent number: 4954616
    Abstract: Use of a guanidine-related compound in solution phase peptide synthesis, the guanidine-related compound including a tetraphenylborate ion and having the general formula: ##STR1## wherein R denotes an organic radical including at least one amine group, and R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 denote inorganic or organic groups independently of each other.
    Type: Grant
    Filed: June 17, 1988
    Date of Patent: September 4, 1990
    Assignee: Solvay & Cie (Societe Anonyme)
    Inventors: Roland Callens, Andre Collin
  • Patent number: 4923966
    Abstract: Use of a guanidine-related compound in solution phase peptide synthesis, the guanidine-related compound comprising a tetraphenylborate ion and having the general formula: ##STR1## wherein R denotes an organic radical comprising at least one amine group.
    Type: Grant
    Filed: June 17, 1988
    Date of Patent: May 8, 1990
    Assignee: Solvay & Cie (Societe Anonyme)
    Inventors: Roland Callens, Andre Collin