Abstract: A method for scale-up of a micro reactor process from lab to production scale comprises using a wall material for a lab reactor having thermal conductivity ?3 W/m·K, and using a wall material for a production reactor having thermal conductivity ?5 W/m·K. Desirably, flow velocity is kept constant, and the height of the production-scale process channel is determined by: H G = 2 × ( A + B ? W + 1 C × ( D h ) ( b - 1 ) ) - 1 h = H G ? ? 0 wherein A B and C are constants; HG is the overall volumetric heat transfer coefficient, Dh is the hydraulic diameter, ?W is the thermal conductivity of the wall, b is the empirically determined power to which the Reynolds number is raised in the equation for the Nusselt criteria (Nu=a·RebPrc) for the type of flow used, and h is the height of the channel, all in the production-scale process; and HG0 is the overall volumetric heat transfer coefficient in the lab-scale process.

Abstract: A plate-type flow reactor device with a first plate (20) having first and second opposing surfaces (22, 24) and one or more through-holes (26); a second plate sealed against the first surface (22) by at least two first O-rings (50); a third plate (40) sealed against the second surface (24) by at least one second O-ring (60); two or more first elongated channels (70) defined between the first surface (22) and the second plate and one or more second elongated channels (80) defined between the second surface (24) and the third plate, wherein each first channel communicates with the at least one second channel (80) via one or more of the through-holes (26) through the first plate (20), and said one first channel (70a) communicates with another first channel (70b) of the two or more first channels (70) only via said at least one second channel (80), and each first channel (70) is individually surrounded by at least one of the first O-rings (50) and the at least one second is individually surrounded by the at least

Abstract: In one aspect the invention relates to reactors and a reactor system that include multiple microstructures each having a first edge and a second edge and an entrance side (18) and including an entrance port (22) and one or more other ports through the entrance side with all of the ports through the entrance side (32a, 32b) arranged in a standard pattern and closer to the first edge than the second edge. Desirably, the entrance port (22) and an exit port (24) are concentric.

Abstract: A plate-type flow reactor device with a first plate (20) having first and second opposing surfaces (22, 24) and one or more through-holes (26); a second plate sealed against the first surface (22) by at least two first O-rings (50); a third plate (40) sealed against the second surface (24) by at least one second O-ring (60); two or more first elongated channels (70) defined between the first surface (22) and the second plate and one or more second elongated channels (80) defined between the second surface (24) and the third plate, wherein each first channel communicates with the at least one second channel (80) via one or more of the through-holes (26) through the first plate (20), and said one first channel (70a) communicates with another first channel (70b) of the two or more first channels (70) only via said at least one second channel (80), and each first channel (70) is individually surrounded by at least one of the first O-rings (50) and the at least one second is individually surrounded by the at least

Abstract: Embodiments of hybrid microfluidic assemblies comprise at least one microstructure that is formed of transparent material and is substantially free of non-transparent material and further comprise at least one microstructure that is formed of non-transparent material and is substantially free of transparent material.

Abstract: A microreactor includes a plurality of interconnected microstructures arranged in m process units with the process units configured to be operable together in parallel. Each of the m process units has a number n of respective process fluid inlets, wherein a number y of the n respective process fluid inlets are connected individually to respective non-manifolded fluid pumps, and wherein a number n minus y of the n respective process fluid inlets are connected to a respective manifolded fluid pump via a manifold, wherein y is an integer from 1 to n?1 inclusive.

Abstract: Embodiments of hybrid microfluidic assemblies comprise at least one microstructure that is formed of transparent material and is substantially free of non-transparent material and further comprise at least one microstructure that is formed of non-transparent material and is substantially free of transparent material.

Abstract: A method is disclosed for the seamless scale-up of a micro reactor process, to transfer lab test to a pilot or production unit, the process comprising the steps of using a wall material for the lab reactor with a thermal conductivity lower than 3 W/m-K, and using a wall material for the production reactor with a thermal conductivity higher than 5 W/m-K.

Abstract: A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

Abstract: A microreactor includes a plurality of interconnected microstructures arranged in m process units with the process units configured to be operable together in parallel. Each of the m process units has a number n of respective process fluid inlets, wherein a number y of the n respective process fluid inlets are connected individually to respective non-manifolded fluid pumps, and wherein a number n minus y of the n respective process fluid inlets are connected to a respective manifolded fluid pump via a manifold, wherein y is an integer from 1 to n-1 inclusive.

Abstract: A microfluidic device comprises at least one reactant passage defined by walls and comprising at least one parallel multiple flow path configuration comprising a group of elementary design patterns being able to provide mixing and/or residence time which are arranged in series with fluid communication so as to constitute flow paths, and in parallel so as to constitute a multiple flow path elementary design pattern, wherein the parallel multiple flow path configuration comprises at least two communicating zones between elementary design patterns of two adjacent parallel flow paths, said communicating zones being in the same plane as that defined by said elementary design patterns between which said communicating zone is placed and allowing passage of fluid in order to minimize mass flow rate difference between adjacent parallel flow paths which have the same flow direction.

Abstract: A heat exchange module is disclosed comprising two metal sheets welded along weld lines defining between them a group of channels disposed side by side substantially in a common plane, intended to be passed through by an exchange fluid and, from the fluidic point of view, being in parallel with each other between two connection orifices of the module. The group of channels has a generally U-shape configuration, which connects together the said connection orifices that are laterally separated from each other.

Abstract: The module is formed from two sheets welded to each other by laser welding. Longitudinal weld beads define between them longitudinal ducts for the flow of a first fluid. The sheets are also joined together by a peripheral weld bead. The weld bead defines, beyond the longitudinal ducts, a transition zone which narrows from the longitudinal ducts up to the gap. Weld spots are previously formed in this zone. Once the welds are completed, the module is formed by the injection of a fluid under pressure through a gap in the weld bead. Utilization for rendering mutually compatible the variations in width of the module during hydroforming in the end regions and for forming, with the transitions zone, a flow distributer to the various channels during operation.