Patents by Inventor Rolf Fendel

Rolf Fendel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-plasmodium parasite antibodies
    Patent number: 10577412
    Abstract: The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against apical membrane antigen 1 (AMA-1). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: March 3, 2020
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Rolf Fendel, Stefan Barth, Rainer Fischer, Andreas Reimann, Dominika Maskus, Torsten Klockenbring
  • Anti-parasitic complexes
    Patent number: 10344082
    Abstract: The technology provided herein relates to novel anti-parasitic complexes, in particular recombinant fusion proteins suitable as human and/or animal drugs against a parasite of the phylum Apicomplexa, in particular against Plasmodium falciparum (P. falciparum) comprising at least one component A and at least one component B, characterized in that component A has a binding activity for cellular surface structures presented on the surface of a parasite of the phylum Apicomplexa or for parasitic antigens presented on a parasitized host cell, and component B is a compound having anti-parasitic activity.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: July 9, 2019
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Rolf Fendel, Stephanie Kapelski, Stefan Barth, Rainer Fischer, Andreas Reimann
  • ANTI-PLASMODIUM PARASITE ANTIBODIES
    Publication number: 20180086823
    Abstract: The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against apical membrane antigen 1 (AMA-1). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.
    Type: Application
    Filed: April 11, 2016
    Publication date: March 29, 2018
    Inventors: Rolf Fendel, Stefan Barth, Rainer Fischer, Andreas Reimann, Dominika Maskus, Torsten Klockenbring
  • ANTI-PARASITIC COMPLEXES
    Publication number: 20170253650
    Abstract: The technology provided herein relates to novel anti-parasitic complexes, in particular recombinant fusion proteins suitable as human and/or animal drugs against a parasite of the phylum Apicomplexa, in particular against Plasmodium falciparum (P. falciparum) comprising at least one component A and at least one component B, characterized in that component A has a binding activity for cellular surface structures presented on the surface of a parasite of the phylum Apicomplexa or for parasitic antigens presented on a parasitized host cell, and component B is a compound having anti-parasitic activity.
    Type: Application
    Filed: August 21, 2015
    Publication date: September 7, 2017
    Applicant: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
    Inventors: Rolf Fendel, Stephanie Kapelski, Stefan Barth, Rainer Fischer, Andreas Reimann
  • Anti-plasmodium parasite antibodies
    Patent number: 9611318
    Abstract: The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against merozoite surface protein 10 (MSP10). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: April 4, 2017
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Rolf Fendel, Torsten Klockenbring, Stefan Barth, Stephanie Kapelski, Dominika Maskus, Rainer Fischer, Andreas Reimann
  • NOVEL ANTI-PLASMODIUM PARASITE ANTIBODIES
    Publication number: 20150197562
    Abstract: The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against merozoite surface protein 10 (MSP10). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.
    Type: Application
    Filed: July 31, 2013
    Publication date: July 16, 2015
    Inventors: Rolf Fendel, Torsten Klockenbring, Stefan Barth, Stephanie Kapelski, Dominika Maskus, Rainer Fischer, Andreas Reimann