Abstract: A independent off bottle single use unit dosage dispensing closure includes a shell attached to a container, an axial movable cap attached to the shell, a sealing member coupled to the cap, and a removable retainer attached to the shell. The shell has an inner guide in communication with the container and the cap is moveable along the guide. The cap has a chamber adapted to dispense material into the container. The chamber is sealed with the sealing member extending across a lower open end thereof, wherein axial movement of the cap along the inner guide member will open the chamber and dispense the contents of the chamber into the container. The retainer prevents relative movement between the cap and the shell until the retainer has been removed.