Patents by Inventor Ron Weiss

Ron Weiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100285584
    Abstract: The present invention provides compositions and methods for programming mammalian cells to perform desired functions. In particular, the present invention provides compositions and methods for programming stem cells to differentiate into a desired cell type. A quorum sensing systems that regulates the expression of cell fate regulators is introduced into mammalian host cells, such as stem cells. The quorum sensing systems generally comprises vectors that express the components of a bacterial quorum sensing pathway, including proteins which catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer, and vectors in which genes encoding cell fate regulators are operably linked to a promoter induced by the autoinducer/regulatory partner complex.
    Type: Application
    Filed: November 1, 2007
    Publication date: November 11, 2010
    Inventors: Ron Weiss, Ihor Lemischka, Priscilla Purnick, Christoph Schaniel, Miles Miller, Patrick Guye
  • Publication number: 20100197006
    Abstract: Disclosed herein are autonomous molecular circuits that can function in cells. The circuits can process logical operations in which one or more input cues are among the operands and produce an appropriate output. Such circuits can be implemented in living cells, e.g., eukaryotic or prokaryotic cells that have been modified to include circuit components. The molecular circuits and cells containing the circuits can be used in a variety of applications including, e.g., diagnostics, therapeutics, and protein production.
    Type: Application
    Filed: October 23, 2009
    Publication date: August 5, 2010
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, TRUSTEES OF PRINCETON UNIVERSITY, Office of Technology Licensing and Intellectual Property
    Inventors: Yaakov Benenson, Ron Weiss, Leonidas Bleris, Zhen Xie