Patents by Inventor Ronald L. Thune

Ronald L. Thune has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuated Pasteurella piscicida vaccine for fish
    Patent number: 6350454
    Abstract: Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion mutations in the aroA gene, the purA gene, or both. These vaccines may be used not only to vaccinate fish against Edwardsiella ictaluri or Pasteurela piscicida, but also to serve as vectors to present antigens from other pathogens to the fish, thereby serving as vaccines against other pathogens as well, with no risk of infection by reversion to the virulent form of the pathogen in which the antigen occurs naturally.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: February 26, 2002
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Ronald L. Thune
  • Attenuated, invasive vaccines against fish pathogens
    Patent number: 6010705
    Abstract: Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion mutations in the aroA gene, the purA gene, or both. These vaccines may be used not only to vaccinate fish against Edwardsiella ictaluri or Pasteurella piscicida, but also to serve as vectors to present antigens from other pathogens to the fish, thereby serving as vaccines against other pathogens as well, with no risk of infection by reversion to the virulent form of the pathogen in which the antigen occurs naturally.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: January 4, 2000
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Ronald L. Thune, Richard K. Cooper